polydipsia Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Excessive thirst manifested by excessive fluid intake. (Human Phenotype Ontology, HP_0001959)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001426
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Genes

29 gene mutations causing the polydipsia phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AQP2 aquaporin 2 (collecting duct)
AQP3 aquaporin 3 (Gill blood group)
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
AVPR2 arginine vasopressin receptor 2
CD63 CD63 molecule
CDK4 cyclin-dependent kinase 4
CLN3 ceroid-lipofuscinosis, neuronal 3
CRH corticotropin releasing hormone
GLIS2 GLIS family zinc finger 2
HPRT1 hypoxanthine phosphoribosyltransferase 1
INS insulin
IRS2 insulin receptor substrate 2
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
LCLAT1 lysocardiolipin acyltransferase 1
LEPR leptin receptor
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NPR3 natriuretic peptide receptor 3
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PSAP prosaposin
REN renin
SCARB2 scavenger receptor class B, member 2
SCTR secretin receptor
SIRT1 sirtuin 1
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
TRPV5 transient receptor potential cation channel, subfamily V, member 5
UOX urate oxidase, pseudogene