polyhydramnios Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A placenta disease that is characterized by an excess of amniotic fluid in the amniotic sac. (Human Disease Ontology, DOID_8488)
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Genes

121 genes co-occuring with the disease polyhydramnios in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
SLC26A3 solute carrier family 26 (anion exchanger), member 3 1.89314
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 1.84818
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 1.80111
STRADA STE20-related kinase adaptor alpha 1.77631
CLCNKB chloride channel, voltage-sensitive Kb 1.69769
BSND barttin CLCNK-type chloride channel accessory beta subunit 1.53965
AFP alpha-fetoprotein 1.41753
AQP9 aquaporin 9 1.19229
BRWD3 bromodomain and WD repeat domain containing 3 1.12024
POF1B premature ovarian failure, 1B 1.11645
ZDHHC15 zinc finger, DHHC-type containing 15 1.10384
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 1.09251
KIAA2022 KIAA2022 1.08202
FLAD1 flavin adenine dinucleotide synthetase 1 1.03788
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 1.03704
ZNF711 zinc finger protein 711 1.02482
MTMR14 myotubularin related protein 14 0.984321
FARSA phenylalanyl-tRNA synthetase, alpha subunit 0.962472
ALG12 ALG12, alpha-1,6-mannosyltransferase 0.956196
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.94369
AQP8 aquaporin 8 0.931656
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 0.917199
CAB39 calcium binding protein 39 0.914727
MAGT1 magnesium transporter 1 0.911845
TEF thyrotrophic embryonic factor 0.901567
LIG3 ligase III, DNA, ATP-dependent 0.847488
GLS2 glutaminase 2 (liver, mitochondrial) 0.838066
TSEN54 TSEN54 tRNA splicing endonuclease subunit 0.836017
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.808539
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.802795
AQP11 aquaporin 11 0.802385
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 0.784345
CSH2 chorionic somatomammotropin hormone 2 0.781069
PSG9 pregnancy specific beta-1-glycoprotein 9 0.761862
MYO5B myosin VB 0.759008
MTM1 myotubularin 1 0.756564
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 0.729357
FGFR3 fibroblast growth factor receptor 3 0.72612
NPPA natriuretic peptide A 0.72612
NEB nebulin 0.712392
LGALS1 lectin, galactoside-binding, soluble, 1 0.701124
C11ORF40 chromosome 11 open reading frame 40 0.687091
REN renin 0.674315
APEH acylaminoacyl-peptide hydrolase 0.636315
ZMPSTE24 zinc metallopeptidase STE24 0.623751
TBX22 T-box 22 0.618268
AQP3 aquaporin 3 (Gill blood group) 0.617877
AGO2 argonaute RISC catalytic component 2 0.616703
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.604981
INS insulin 0.60069
DIO3 deiodinase, iodothyronine, type III 0.594064
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 0.587054
GGCT gamma-glutamylcyclotransferase 0.585108
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 0.582773
STK11 serine/threonine kinase 11 0.575383
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.573439
PTER phosphotriesterase related 0.561392
VRK1 vaccinia related kinase 1 0.560616
ARSE arylsulfatase E (chondrodysplasia punctata 1) 0.557509
AQP1 aquaporin 1 (Colton blood group) 0.547032
HRAS Harvey rat sarcoma viral oncogene homolog 0.542379
MEOX2 mesenchyme homeobox 2 0.53657
FOXF1 forkhead box F1 0.52729
ERCC6 excision repair cross-complementation group 6 0.522659
LAX1 lymphocyte transmembrane adaptor 1 0.519575
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 0.517649
ACTA1 actin, alpha 1, skeletal muscle 0.514571
POU3F4 POU class 3 homeobox 4 0.505356
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.496175
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 0.460883
PLAGL1 pleiomorphic adenoma gene-like 1 0.459751
TCOF1 Treacher Collins-Franceschetti syndrome 1 0.449947
PRL prolactin 0.446935
ACHE acetylcholinesterase (Yt blood group) 0.430768
SIX2 SIX homeobox 2 0.42214
COL2A1 collagen, type II, alpha 1 0.411657
SRPX2 sushi-repeat containing protein, X-linked 2 0.394863
SHH sonic hedgehog 0.386308
OR6B2 olfactory receptor, family 6, subfamily B, member 2 0.384079
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 0.383708
GPC3 glypican 3 0.381481
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.37629
PSIP1 PC4 and SFRS1 interacting protein 1 0.37555
MKKS McKusick-Kaufman syndrome 0.374809
PAX3 paired box 3 0.368888
RYR1 ryanodine receptor 1 (skeletal) 0.365932
FGR FGR proto-oncogene, Src family tyrosine kinase 0.359289
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.335412
SHOX short stature homeobox 0.332121
WDR20 WD repeat domain 20 0.331756
PRIMA1 proline rich membrane anchor 1 0.32373
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.320817
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.320454
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 0.307033
SCNN1G sodium channel, non voltage gated 1 gamma subunit 0.301615
CHD7 chromodomain helicase DNA binding protein 7 0.294772
BIN1 bridging integrator 1 0.28831
EFNB2 ephrin-B2 0.284013
ITGB4 integrin, beta 4 0.272597
AMPH amphiphysin 0.271174
STAR steroidogenic acute regulatory protein 0.26514
HMOX2 heme oxygenase 2 0.258064
TPM3 tropomyosin 3 0.242245
RHCE Rh blood group, CcEe antigens 0.238403
MAP2K1 mitogen-activated protein kinase kinase 1 0.23666
DLK1 delta-like 1 homolog (Drosophila) 0.233878
ITGA6 integrin, alpha 6 0.228679
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.224196
FGFR2 fibroblast growth factor receptor 2 0.22145
NUMBL numb homolog (Drosophila)-like 0.212271
LMNA lamin A/C 0.209918
WNT1 wingless-type MMTV integration site family, member 1 0.204263
IGF2R insulin-like growth factor 2 receptor 0.202946
EXTL3 exostosin-like glycosyltransferase 3 0.198386
NOTCH1 notch 1 0.192971
TSC1 tuberous sclerosis 1 0.188326
FLT4 fms-related tyrosine kinase 4 0.18621
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.180937
ALB albumin 0.171286
SOS1 son of sevenless homolog 1 (Drosophila) 0.159658
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.157602