polyp Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Discrete abnormal tissue masses that protrude into the lumen of the DIGESTIVE TRACT or the RESPIRATORY TRACT. Polyps can be spheroidal, hemispheroidal, or irregular mound-shaped structures attached to the MUCOUS MEMBRANE of the lumen wall either by a stalk, pedunculus, or by a broad base.|A usually exophytic mass attached to the underlying tissue by a broad base or a thin stalk. Polyps can be neoplastic or non-neoplastic. Neoplastic polyps usually represent proliferations of the epithelium, and are commonly seen in the gastrointestinal tract. Polyps of the gastrointestinal tract are often called adenomas, are associated with dysplasia, and may eventually transform into carcinomas. Non-neoplastic polyps may be inflammatory, degenerative, or the result of malformations. -- 2004|A usually exophytic mass attached to the underlying tissue by a broad base or a thin stalk. Polyps can be neoplastic or non-neoplastic. Neoplastic polyps usually represent proliferations of the epithelium, and are commonly seen in the gastrointestinal tract. Polyps of the gastrointestinal tract are often called adenomas, are associated with dysplasia, and may eventually transform into carcinomas. Non-neoplastic polyps may be inflammatory, degenerative, or the result of malformations. (Experimental Factor Ontology, EFO_0000662)
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Genes

80 genes co-occuring with the biological term polyp in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACKR3 atypical chemokine receptor 3
ADIPOQ adiponectin, C1Q and collagen domain containing
ALOX12 arachidonate 12-lipoxygenase
APC adenomatous polyposis coli
ATF6 activating transcription factor 6
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BPIFA1 BPI fold containing family A, member 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
CALB2 calbindin 2
CCL11 chemokine (C-C motif) ligand 11
CCL13 chemokine (C-C motif) ligand 13
CCL17 chemokine (C-C motif) ligand 17
CCL2 chemokine (C-C motif) ligand 2
CCL26 chemokine (C-C motif) ligand 26
CD34 CD34 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CDKN2A cyclin-dependent kinase inhibitor 2A
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHIA chitinase, acidic
CLDN5 claudin 5
CRP C-reactive protein, pentraxin-related
CTSD cathepsin D
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
DICER1 dicer 1, ribonuclease type III
DKK1 dickkopf WNT signaling pathway inhibitor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FLT1 fms-related tyrosine kinase 1
GAPDH glyceraldehyde-3-phosphate dehydrogenase
HTT huntingtin
IFNG interferon, gamma
IGF1R insulin-like growth factor 1 receptor
IL4 interleukin 4
INS insulin
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KLF6 Kruppel-like factor 6
KRAS Kirsten rat sarcoma viral oncogene homolog
LEP leptin
LEPR leptin receptor
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MUC1 mucin 1, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
NOS2 nitric oxide synthase 2, inducible
NOX1 NADPH oxidase 1
NOX4 NADPH oxidase 4
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PNKP polynucleotide kinase 3'-phosphatase
PPARG peroxisome proliferator-activated receptor gamma
PRKCA protein kinase C, alpha
PTEN phosphatase and tensin homolog
PTGDR2 prostaglandin D2 receptor 2
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
S100A9 S100 calcium binding protein A9
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SFRP2 secreted frizzled-related protein 2
SOD1 superoxide dismutase 1, soluble
SPINK5 serine peptidase inhibitor, Kazal type 5
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR3 toll-like receptor 3
TLR9 toll-like receptor 9
TNC tenascin C
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TSLP thymic stromal lymphopoietin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A