polyps Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Discrete abnormal tissue masses that protrude into the lumen of the DIGESTIVE TRACT or the RESPIRATORY TRACT. Polyps can be spheroidal, hemispheroidal, or irregular mound-shaped structures attached to the MUCOUS MEMBRANE of the lumen wall either by a stalk, pedunculus, or by a broad base.|A usually exophytic mass attached to the underlying tissue by a broad base or a thin stalk. Polyps can be neoplastic or non-neoplastic. Neoplastic polyps usually represent proliferations of the epithelium, and are commonly seen in the gastrointestinal tract. Polyps of the gastrointestinal tract are often called adenomas, are associated with dysplasia, and may eventually transform into carcinomas. Non-neoplastic polyps may be inflammatory, degenerative, or the result of malformations. -- 2004|A usually exophytic mass attached to the underlying tissue by a broad base or a thin stalk. Polyps can be neoplastic or non-neoplastic. Neoplastic polyps usually represent proliferations of the epithelium, and are commonly seen in the gastrointestinal tract. Polyps of the gastrointestinal tract are often called adenomas, are associated with dysplasia, and may eventually transform into carcinomas. Non-neoplastic polyps may be inflammatory, degenerative, or the result of malformations. (Experimental Factor Ontology, EFO_0000662)
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Genes

236 genes co-occuring with the biological term polyps in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABI1 abl-interactor 1
ADAM33 ADAM metallopeptidase domain 33
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
AHR aryl hydrocarbon receptor
ALOX5 arachidonate 5-lipoxygenase
ANG angiogenin, ribonuclease, RNase A family, 5
ANXA1 annexin A1
APC adenomatous polyposis coli
APOM apolipoprotein M
AQP1 aquaporin 1 (Colton blood group)
AQP5 aquaporin 5
ARSA arylsulfatase A
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMPR1A bone morphogenetic protein receptor, type IA
BPIFA1 BPI fold containing family A, member 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BSG basigin (Ok blood group)
BVES blood vessel epicardial substance
CA9 carbonic anhydrase IX
CAMP cathelicidin antimicrobial peptide
CCL11 chemokine (C-C motif) ligand 11
CCL17 chemokine (C-C motif) ligand 17
CCL2 chemokine (C-C motif) ligand 2
CCL23 chemokine (C-C motif) ligand 23
CCL24 chemokine (C-C motif) ligand 24
CCL26 chemokine (C-C motif) ligand 26
CCNE1 cyclin E1
CCP110 centriolar coiled coil protein 110kDa
CD34 CD34 molecule
CD69 CD69 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDX1 caudal type homeobox 1
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHIA chitinase, acidic
CHIT1 chitinase 1 (chitotriosidase)
CIITA class II, major histocompatibility complex, transactivator
CLCN2 chloride channel, voltage-sensitive 2
CLCN3 chloride channel, voltage-sensitive 3
CLDN18 claudin 18
CLEC7A C-type lectin domain family 7, member A
COL26A1 collagen, type XXVI, alpha 1
CRLF2 cytokine receptor-like factor 2
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSE cathepsin E
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYSLTR1 cysteinyl leukotriene receptor 1
DCN decorin
DEFB4A defensin, beta 4A
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F13A1 coagulation factor XIII, A1 polypeptide
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXJ1 forkhead box J1
FOXP3 forkhead box P3
GAST gastrin
GATA3 GATA binding protein 3
GDF15 growth differentiation factor 15
GH1 growth hormone 1
GHR growth hormone receptor
GPR183 G protein-coupled receptor 183
GREM1 gremlin 1, DAN family BMP antagonist
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-G major histocompatibility complex, class I, G
HOTAIR HOX transcript antisense RNA
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
ICAM1 intercellular adhesion molecule 1
IFITM1 interferon induced transmembrane protein 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP1 insulin-like growth factor binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
IGHE immunoglobulin heavy constant epsilon
IL17A interleukin 17A
IL17B interleukin 17B
IL17RA interleukin 17 receptor A
IL18 interleukin 18
IL19 interleukin 19
IL1B interleukin 1, beta
IL22RA1 interleukin 22 receptor, alpha 1
IL33 interleukin 33
IL4 interleukin 4
IL5 interleukin 5
IL6 interleukin 6
IL6R interleukin 6 receptor
ILK integrin-linked kinase
INS insulin
IPO13 importin 13
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITLN1 intelectin 1 (galactofuranose binding)
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT20 keratin 20, type I
KRT7 keratin 7, type II
LCN2 lipocalin 2
LCT lactase
LEP leptin
LGALS1 lectin, galactoside-binding, soluble, 1
LTF lactotransferrin
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MCAM melanoma cell adhesion molecule
MIR145 microRNA 145
MIR181B1 microRNA 181b-1
MIR181B2 microRNA 181b-2
MIR192 microRNA 192
MIR21 microRNA 21
MIR320A microRNA 320a
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MSH2 mutS homolog 2
MSH3 mutS homolog 3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC1 mucin 1, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
MUTYH mutY homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYOG myogenin (myogenic factor 4)
NES nestin
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP3 NLR family, pyrin domain containing 3
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OGG1 8-oxoguanine DNA glycosylase
OLFM4 olfactomedin 4
PAEP progestagen-associated endometrial protein
PCSK1 proprotein convertase subtilisin/kexin type 1
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEBP1 phosphatidylethanolamine binding protein 1
PGR progesterone receptor
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PON1 paraoxonase 1
POSTN periostin, osteoblast specific factor
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRKCA protein kinase C, alpha
PSCA prostate stem cell antigen
PTEN phosphatase and tensin homolog
PTGDR prostaglandin D2 receptor (DP)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAD51 RAD51 recombinase
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RETN resistin
RNASE3 ribonuclease, RNase A family, 3
RORC RAR-related orphan receptor C
RUNX2 runt-related transcription factor 2
RUNX3 runt-related transcription factor 3
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SELE selectin E
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP1 secreted frizzled-related protein 1
SFTPA1 surfactant protein A1
SFTPB surfactant protein B
SFTPC surfactant protein C
SFTPD surfactant protein D
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SMAD4 SMAD family member 4
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOX2 SRY (sex determining region Y)-box 2
SRPX sushi-repeat containing protein, X-linked
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK11 serine/threonine kinase 11
TBX21 T-box 21
TERT telomerase reverse transcriptase
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TMPRSS15 transmembrane protease, serine 15
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TP53 tumor protein p53
TP73 tumor protein p73
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TSLP thymic stromal lymphopoietin
UBE3C ubiquitin protein ligase E3C
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VIM vimentin
VIPR2 vasoactive intestinal peptide receptor 2
WNT5A wingless-type MMTV integration site family, member 5A