polyuria Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An increased rate of urine production. (Human Phenotype Ontology, HP_0000103)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001762
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Genes

72 gene mutations causing the polyuria phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADCY6 adenylate cyclase 6
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTRAP angiotensin II receptor-associated protein
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APRT adenine phosphoribosyltransferase
AQP2 aquaporin 2 (collecting duct)
AQP3 aquaporin 3 (Gill blood group)
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
AVP arginine vasopressin
AVPR2 arginine vasopressin receptor 2
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BSND barttin CLCNK-type chloride channel accessory beta subunit
CD63 CD63 molecule
CDK4 cyclin-dependent kinase 4
CLCN5 chloride channel, voltage-sensitive 5
CLCNKB chloride channel, voltage-sensitive Kb
CLDN2 claudin 2
CLN3 ceroid-lipofuscinosis, neuronal 3
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CRH corticotropin releasing hormone
CTSA cathepsin A
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
DRD2 dopamine receptor D2
FBN1 fibrillin 1
FXYD4 FXYD domain containing ion transport regulator 4
GCG glucagon
GDF15 growth differentiation factor 15
GLIS2 GLIS family zinc finger 2
HNF1A HNF1 homeobox A
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
IDE insulin-degrading enzyme
INS insulin
INSL5 insulin-like 5
IRS2 insulin receptor substrate 2
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
LEP leptin
LEPR leptin receptor
LIN7C lin-7 homolog C (C. elegans)
MPV17 MpV17 mitochondrial inner membrane protein
MTSS1 metastasis suppressor 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NPR3 natriuretic peptide receptor 3
OIT3 oncoprotein induced transcript 3
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PSAP prosaposin
PTTG1 pituitary tumor-transforming 1
REN renin
SCARB2 scavenger receptor class B, member 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCTR secretin receptor
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC4A11 solute carrier family 4, sodium borate transporter, member 11
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
TFCP2L1 transcription factor CP2-like 1
TMEM27 transmembrane protein 27
TRPV5 transient receptor potential cation channel, subfamily V, member 5
UMOD uromodulin
UOX urate oxidase, pseudogene
UPK2 uroplakin 2
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WNK4 WNK lysine deficient protein kinase 4
WWTR1 WW domain containing transcription regulator 1