pon1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description paraoxonase 1|The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3. [provided by RefSeq, Oct 2008] (NCBI Entrez Gene Database, 5444)
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Genes

51 genes co-occuring with the biological term pon1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE angiotensin I converting enzyme
ADIPOQ adiponectin, C1Q and collagen domain containing
AGER advanced glycosylation end product-specific receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
APOA2 apolipoprotein A-II
APOA4 apolipoprotein A-IV
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOE apolipoprotein E
CCL2 chemokine (C-C motif) ligand 2
CES1 carboxylesterase 1
CST3 cystatin C
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
FTO fat mass and obesity associated
GLO1 glyoxalase I
GPX1 glutathione peroxidase 1
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
HPBP phosphate binding apolipoprotein
IDE insulin-degrading enzyme
IGF2 insulin-like growth factor 2
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
LEP leptin
LEPR leptin receptor
MIR616 microRNA 616
MMP3 matrix metallopeptidase 3
MPO myeloperoxidase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS3 nitric oxide synthase 3 (endothelial cell)
NQO1 NAD(P)H dehydrogenase, quinone 1
OGG1 8-oxoguanine DNA glycosylase
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PON1 paraoxonase 1
PON2 paraoxonase 2
PON3 paraoxonase 3
POU2F1 POU class 2 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PTGER3 prostaglandin E receptor 3 (subtype EP3)
SAA1 serum amyloid A1
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SOD2 superoxide dismutase 2, mitochondrial
XDH xanthine dehydrogenase