positive regulation of GTPase activity Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that activates or increases the activity of a GTPase. (Gene Ontology, GO_0043547)
External Link http://amigo.geneontology.org/amigo/term/GO:0043547
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Genes

112 genes participating in the positive regulation of GTPase activity biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ABR active BCR-related
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AGRN agrin
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP11A Rho GTPase activating protein 11A
ARHGAP11B Rho GTPase activating protein 11B
ARHGAP42 Rho GTPase activating protein 42
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BCAR3 breast cancer anti-estrogen resistance 3
BCR breakpoint cluster region
CAV2 caveolin 2
CCDC125 coiled-coil domain containing 125
CCL11 chemokine (C-C motif) ligand 11
CCL19 chemokine (C-C motif) ligand 19
CCL24 chemokine (C-C motif) ligand 24
CCL26 chemokine (C-C motif) ligand 26
CORO1C coronin, actin binding protein, 1C
CXCL13 chemokine (C-X-C motif) ligand 13
DOCK10 dedicator of cytokinesis 10
DOCK11 dedicator of cytokinesis 11
DOCK8 dedicator of cytokinesis 8
DOCK9 dedicator of cytokinesis 9
DVL3 dishevelled segment polarity protein 3
ECT2 epithelial cell transforming 2
EPHA1 EPH receptor A1
EPHA2 EPH receptor A2
EVI5 ecotropic viral integration site 5
EVI5L ecotropic viral integration site 5-like
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FOXJ1 forkhead box J1
GNB5 guanine nucleotide binding protein (G protein), beta 5
GPR65 G protein-coupled receptor 65
HRAS Harvey rat sarcoma viral oncogene homolog
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
LARS1 leucyl-tRNA synthetase 1
LIMS1 LIM and senescent cell antigen-like domains 1
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MMUT methylmalonyl-CoA mutase
MTSS2 MTSS I-BAR domain containing 2
NDEL1 nudE neurodevelopment protein 1-like 1
NF1 neurofibromin 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
ODAM odontogenic, ameloblast asssociated
PDZD2 PDZ domain containing 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKP4 plakophilin 4
PLXNB1 plexin B1
PRPF38B pre-mRNA processing factor 38B
PRTN3 proteinase 3
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RACK1 receptor for activated C kinase 1
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
RANGAP1 Ran GTPase activating protein 1
RAP1A RAP1A, member of RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
REPS1 RALBP1 associated Eps domain containing 1
RGPD1 RANBP2-like and GRIP domain containing 1
RGS1 regulator of G-protein signaling 1
RGS10 regulator of G-protein signaling 10
RGS16 regulator of G-protein signaling 16
RGS6 regulator of G-protein signaling 6
RGS7 regulator of G-protein signaling 7
RGS8 regulator of G-protein signaling 8
RHOG ras homolog family member G
RIC1 RAB6A GEF complex partner 1
RSU1 Ras suppressor protein 1
RTN4R reticulon 4 receptor
S100A10 S100 calcium binding protein A10
SCRIB scribbled planar cell polarity protein
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SGSM2 small G protein signaling modulator 2
SGSM3 small G protein signaling modulator 3
SH3BP1 SH3-domain binding protein 1
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
SNX13 sorting nexin 13
SNX18 sorting nexin 18
SNX9 sorting nexin 9
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TBC1D2 TBC1 domain family, member 2
TBC1D20 TBC1 domain family, member 20
TBC1D30 TBC1 domain family, member 30
TBC1D7 TBC1 domain family, member 7
TGM2 transglutaminase 2
THY1 Thy-1 cell surface antigen
TIAM1 T-cell lymphoma invasion and metastasis 1
TSC1 tuberous sclerosis 1
USP17L2 ubiquitin specific peptidase 17-like family member 2
USP6NL USP6 N-terminal like
ZC3H15 zinc finger CCCH-type containing 15