positive regulation of MAPK cascade Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade. (Gene Ontology, GO_0043410)
External Link http://amigo.geneontology.org/amigo/term/GO_0043410
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Genes

311 genes participating in the positive regulation of MAPK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACKR3 atypical chemokine receptor 3
ADAM8 ADAM metallopeptidase domain 8
ADAM9 ADAM metallopeptidase domain 9
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ADRA2C adrenoceptor alpha 2C
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGER advanced glycosylation end product-specific receptor
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALOX15 arachidonate 15-lipoxygenase
AMH anti-Mullerian hormone
ANGPT1 angiopoietin 1
APELA apelin receptor early endogenous ligand
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ARHGAP8 Rho GTPase activating protein 8
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ART4 ADP-ribosyltransferase 4 (Dombrock blood group)
AVPI1 arginine vasopressin-induced 1
AVPR1B arginine vasopressin receptor 1B
BCAR3 breast cancer anti-estrogen resistance 3
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMPER BMP binding endothelial regulator
BRAF B-Raf proto-oncogene, serine/threonine kinase
C5AR1 complement component 5a receptor 1
CALCR calcitonin receptor
CARD9 caspase recruitment domain family, member 9
CARTPT CART prepropeptide
CAV2 caveolin 2
CCL1 chemokine (C-C motif) ligand 1
CCL11 chemokine (C-C motif) ligand 11
CCL13 chemokine (C-C motif) ligand 13
CCL14 chemokine (C-C motif) ligand 14
CCL15 chemokine (C-C motif) ligand 15
CCL16 chemokine (C-C motif) ligand 16
CCL17 chemokine (C-C motif) ligand 17
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL21 chemokine (C-C motif) ligand 21
CCL22 chemokine (C-C motif) ligand 22
CCL23 chemokine (C-C motif) ligand 23
CCL24 chemokine (C-C motif) ligand 24
CCL25 chemokine (C-C motif) ligand 25
CCL26 chemokine (C-C motif) ligand 26
CCL3 chemokine (C-C motif) ligand 3
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CCL4 chemokine (C-C motif) ligand 4
CCL4L1 chemokine (C-C motif) ligand 4-like 1
CCL5 chemokine (C-C motif) ligand 5
CCL7 chemokine (C-C motif) ligand 7
CCL8 chemokine (C-C motif) ligand 8
CCN2 cellular communication network factor 2
CCR1 chemokine (C-C motif) receptor 1
CCR7 chemokine (C-C motif) receptor 7
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD81 CD81 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CIB1 calcium and integrin binding 1 (calmyrin)
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSF1R colony stimulating factor 1 receptor
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL17 chemokine (C-X-C motif) ligand 17
DAB2IP DAB2 interacting protein
DDR1 discoidin domain receptor tyrosine kinase 1
DDR2 discoidin domain receptor tyrosine kinase 2
DDT D-dopachrome tautomerase
DENND2B DENN domain containing 2B
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DIRAS1 DIRAS family, GTP-binding RAS-like 1
DIRAS2 DIRAS family, GTP-binding RAS-like 2
DOK2 docking protein 2, 56kDa
DOK3 docking protein 3
DOK4 docking protein 4
DOK5 docking protein 5
DOK6 docking protein 6
DRD4 dopamine receptor D4
DSTYK dual serine/threonine and tyrosine protein kinase
DUSP19 dual specificity phosphatase 19
EDN1 endothelin 1
EDN3 endothelin 3
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ELANE elastase, neutrophil expressed
EPGN epithelial mitogen
EPHA8 EPH receptor A8
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ERP29 endoplasmic reticulum protein 29
ETFA electron-transfer-flavoprotein, alpha polypeptide
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM150A family with sequence similarity 150, member A
FAM150B family with sequence similarity 150, member B
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCRL3 Fc receptor-like 3
FERMT2 fermitin family member 2
FFAR4 free fatty acid receptor 4
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF18 fibroblast growth factor 18
FGF19 fibroblast growth factor 19
FGF2 fibroblast growth factor 2 (basic)
FGF21 fibroblast growth factor 21
FGF4 fibroblast growth factor 4
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FGG fibrinogen gamma chain
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
FPR2 formyl peptide receptor 2
FSHR follicle stimulating hormone receptor
GAREM1 GRB2 associated regulator of MAPK1 subtype 1
GAS6 growth arrest-specific 6
GATA4 GATA binding protein 4
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GDF15 growth differentiation factor 15
GFRAL GDNF family receptor alpha like
GH1 growth hormone 1
GHR growth hormone receptor
GHRL ghrelin/obestatin prepropeptide
GLIPR2 GLI pathogenesis-related 2
GPER1 G protein-coupled estrogen receptor 1
GPNMB glycoprotein (transmembrane) nmb
GPR183 G protein-coupled receptor 183
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GPR37L1 G protein-coupled receptor 37 like 1
GPR55 G protein-coupled receptor 55
GRM4 glutamate receptor, metabotropic 4
GSDME gasdermin E
HAND2 heart and neural crest derivatives expressed 2
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HRAS Harvey rat sarcoma viral oncogene homolog
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGFBP6 insulin-like growth factor binding protein 6
IL11 interleukin 11
IL1B interleukin 1, beta
IL26 interleukin 26
IL34 interleukin 34
IL6 interleukin 6
INAVA innate immunity activator
INS insulin
INSR insulin receptor
IQGAP1 IQ motif containing GTPase activating protein 1
IRAK1 interleukin-1 receptor-associated kinase 1
JCAD junctional cadherin 5 associated
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHDC10 kelch domain containing 10
KSR1 kinase suppressor of ras 1
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LAPTM5 lysosomal protein transmembrane 5
LEP leptin
LGALS9 lectin, galactoside-binding, soluble, 9
LIF leukemia inhibitory factor
LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2
LPAR1 lysophosphatidic acid receptor 1
LRRK2 leucine-rich repeat kinase 2
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K5 mitogen-activated protein kinase kinase 5
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAPK3 mitogen-activated protein kinase 3
MARCO macrophage receptor with collagenous structure
MEF2C myocyte enhancer factor 2C
MFAP3 microfibrillar-associated protein 3
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MID1 midline 1
MMP8 matrix metallopeptidase 8
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MST1R macrophage stimulating 1 receptor
MT3 metallothionein 3
MTURN maturin, neural progenitor differentiation regulator homolog (Xenopus)
MUSK muscle, skeletal, receptor tyrosine kinase
MYDGF myeloid-derived growth factor
NDRG4 NDRG family member 4
NECAB2 N-terminal EF-hand calcium binding protein 2
NEK10 NIMA-related kinase 10
NELL1 NEL-like 1 (chicken)
NOD2 nucleotide-binding oligomerization domain containing 2
NODAL nodal growth differentiation factor
NOTCH1 notch 1
NOTCH2 notch 2
NPNT nephronectin
NRG1 neuregulin 1
NTF3 neurotrophin 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OPRM1 opioid receptor, mu 1
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4
OSM oncostatin M
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDCD10 programmed cell death 10
PDE8A phosphodiesterase 8A
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFC platelet derived growth factor C
PDGFD platelet derived growth factor D
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PELI2 pellino E3 ubiquitin protein ligase family member 2
PHB prohibitin
PHB2 prohibitin 2
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G5 phospholipase A2, group V
PLCE1 phospholipase C, epsilon 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRKCA protein kinase C, alpha
PRKCZ protein kinase C, zeta
PRKD2 protein kinase D2
PRXL2C peroxiredoxin like 2C
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRJ protein tyrosine phosphatase, receptor type, J
PYCARD PYD and CARD domain containing
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAMP3 receptor (G protein-coupled) activity modifying protein 3
RAP1A RAP1A, member of RAS oncogene family
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RET ret proto-oncogene
RIT2 Ras-like without CAAX 2
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
ROR1 receptor tyrosine kinase-like orphan receptor 1
ROR2 receptor tyrosine kinase-like orphan receptor 2
RYK receptor-like tyrosine kinase
S100A12 S100 calcium binding protein A12
S100A7 S100 calcium binding protein A7
SCIMP SLP adaptor and CSK interacting membrane protein
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC30A10 solute carrier family 30, member 10
SOD1 superoxide dismutase 1, soluble
SOX2 SRY (sex determining region Y)-box 2
SPRY2 sprouty homolog 2 (Drosophila)
STK25 serine/threonine kinase 25
SYT14P1 synaptotagmin XIV pseudogene 1
TAOK1 TAO kinase 1
TAOK2 TAO kinase 2
TAOK3 TAO kinase 3
TBX1 T-box 1
TDGF1 teratocarcinoma-derived growth factor 1
TEK TEK tyrosine kinase, endothelial
TENM1 teneurin transmembrane protein 1
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFBR1 transforming growth factor, beta receptor 1
THBS1 thrombospondin 1
THPO thrombopoietin
TIPE3 TNF alpha induced protein 8 like 3
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TMEM106A transmembrane protein 106A
TNF tumor necrosis factor
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TPD52L1 tumor protein D52-like 1
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
TREM2 triggering receptor expressed on myeloid cells 2
TRIM5 tripartite motif containing 5
VEGFA vascular endothelial growth factor A
WWC1 WW and C2 domain containing 1
XCL1 chemokine (C motif) ligand 1
XCL2 chemokine (C motif) ligand 2
ZNF622 zinc finger protein 622