positive regulation of NF-kappaB transcription factor activity Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB. (Gene Ontology, GO_0051092)
External Link http://amigo.geneontology.org/amigo/term/GO:0051092
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Genes

106 genes participating in the positive regulation of NF-kappaB transcription factor activity biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AGER advanced glycosylation end product-specific receptor
AGXT alanine-glyoxylate aminotransferase
AIM2 absent in melanoma 2
ALK anaplastic lymphoma receptor tyrosine kinase
AREG amphiregulin
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
BCL10 B-cell CLL/lymphoma 10
BTK Bruton agammaglobulinemia tyrosine kinase
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAPN3 calpain 3, (p94)
CARD11 caspase recruitment domain family, member 11
CARD14 caspase recruitment domain family, member 14
CARD16 caspase recruitment domain family, member 16
CARD9 caspase recruitment domain family, member 9
CD40LG CD40 ligand
CFLAR CASP8 and FADD-like apoptosis regulator
CHUK conserved helix-loop-helix ubiquitous kinase
CIB1 calcium and integrin binding 1 (calmyrin)
CLOCK clock circadian regulator
CLU clusterin
CRNN cornulin
DDRGK1 DDRGK domain containing 1
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ERC1 ELKS/RAB6-interacting/CAST family member 1
FER fer (fps/fes related) tyrosine kinase
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL18RAP interleukin 18 receptor accessory protein
IL1B interleukin 1, beta
IRAK1 interleukin-1 receptor-associated kinase 1
LGALS9 lectin, galactoside-binding, soluble, 9
LTF lactotransferrin
MALT1 MALT1 paracaspase
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MID2 midline 2
MTDH metadherin
MTPN myotrophin
MYD88 myeloid differentiation primary response 88
NLRC4 NLR family, CARD domain containing 4
NLRP3 NLR family, pyrin domain containing 3
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRDX3 peroxiredoxin 3
PRKCH protein kinase C, eta
PRKCI protein kinase C, iota
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKD2 protein kinase D2
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PYCARD PYD and CARD domain containing
RAB7B RAB7B, member RAS oncogene family
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHEBL1 Ras homolog enriched in brain like 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
RIPK4 receptor-interacting serine-threonine kinase 4
RNF25 ring finger protein 25
RNF31 ring finger protein 31
RORA RAR-related orphan receptor A
RPS3 ribosomal protein S3
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RTKN2 rhotekin 2
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SPHK1 sphingosine kinase 1
TANK TRAF family member-associated NFKB activator
TERF2IP telomeric repeat binding factor 2, interacting protein
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TRAF1 TNF receptor-associated factor 1
TRAF5 TNF receptor-associated factor 5
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM13 tripartite motif containing 13
TRIM14 tripartite motif containing 14
TRIM15 tripartite motif containing 15
TRIM22 tripartite motif containing 22
TRIM25 tripartite motif containing 25
TRIM32 tripartite motif containing 32
TRIM37 tripartite motif containing 37
TRIM38 tripartite motif containing 38
TRIM5 tripartite motif containing 5
TRIM52 tripartite motif containing 52
TRIM62 tripartite motif containing 62
TRIM8 tripartite motif containing 8
UBE2N ubiquitin-conjugating enzyme E2N
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
WNT5A wingless-type MMTV integration site family, member 5A
ZBTB7A zinc finger and BTB domain containing 7A