positive regulation of T cell activation Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that activates or increases the frequency, rate or extent of T cell activation. (Gene Ontology, GO_0050870)
External Link http://amigo.geneontology.org/amigo/term/GO:0050870
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Genes

112 genes participating in the positive regulation of T cell activation biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTL6A actin-like 6A
ACTL6B actin-like 6B
AIF1 allograft inflammatory factor 1
ANXA1 annexin A1
ARID1A AT rich interactive domain 1A (SWI-like)
ARID1B AT rich interactive domain 1B (SWI1-like)
ARID2 AT rich interactive domain 2 (ARID, RFX-like)
B2M beta-2-microglobulin
BRD7 bromodomain containing 7
CCDC88B coiled-coil domain containing 88B
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCR2 chemokine (C-C motif) receptor 2
CCR7 chemokine (C-C motif) receptor 7
CD1D CD1d molecule
CD209 CD209 molecule
CD274 CD274 molecule
CD276 CD276 molecule
CD28 CD28 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD40LG CD40 ligand
CD46 CD46 molecule, complement regulatory protein
CD47 CD47 molecule
CD6 CD6 molecule
CD70 CD70 molecule
CD80 CD80 molecule
CD81 CD81 molecule
CD86 CD86 molecule
CYRIB CYFIP related Rac1 interactor B
DOCK8 dedicator of cytokinesis 8
FBXO38 F-box protein 38
FCHO1 FCH domain only 1
FLOT2 flotillin 2
GATA3 GATA binding protein 3
HLA-A major histocompatibility complex, class I, A
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IL12B interleukin 12B
IL15 interleukin 15
IL1B interleukin 1, beta
IL21 interleukin 21
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL36B interleukin 36, beta
IL4 interleukin 4
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
IL7 interleukin 7
JAK2 Janus kinase 2
KLHL22 kelch-like family member 22
LCK LCK proto-oncogene, Src family tyrosine kinase
LEP leptin
LGALS9 lectin, galactoside-binding, soluble, 9
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
MDK midkine (neurite growth-promoting factor 2)
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NCKAP1L NCK-associated protein 1-like
NOD2 nucleotide-binding oligomerization domain containing 2
NR5A2 nuclear receptor subfamily 5, group A, member 2
PBRM1 polybromo 1
PDCD1LG2 programmed cell death 1 ligand 2
PHF10 PHD finger protein 10
POTEF POTE ankyrin domain family, member F
PPY pancreatic polypeptide
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCQ protein kinase C, theta
PTPRC protein tyrosine phosphatase, receptor type, C
PYCARD PYD and CARD domain containing
RHOH ras homolog family member H
SIRPA signal-regulatory protein alpha
SIRPB1 signal-regulatory protein beta 1
SIRPG signal-regulatory protein gamma
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
TFRC transferrin receptor
THY1 Thy-1 cell surface antigen
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TYK2 tyrosine kinase 2
VCAM1 vascular cell adhesion molecule 1
XBP1 X-box binding protein 1
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB1 zinc finger and BTB domain containing 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZP3 zona pellucida glycoprotein 3 (sperm receptor)
ZP4 zona pellucida glycoprotein 4