positive regulation of autophagy Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. (Gene Ontology, GO_0010508)
External Link http://amigo.geneontology.org/amigo/term/GO:0010508
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Genes

100 genes participating in the positive regulation of autophagy biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AMBRA1 autophagy/beclin-1 regulator 1
ATF6 activating transcription factor 6
ATG101 autophagy related 101
ATG13 autophagy related 13
ATG2A autophagy related 2A
BAD BCL2-associated agonist of cell death
BECN1 beclin 1, autophagy related
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C9ORF72 chromosome 9 open reading frame 72
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CCNY cyclin Y
CDK16 cyclin-dependent kinase 16
DAPK1 death-associated protein kinase 1
DCN decorin
DEPDC5 DEP domain containing 5
DEPTOR DEP domain containing MTOR-interacting protein
DHRSX dehydrogenase/reductase (SDR family) X-linked
ENDOG endonuclease G
FBXO7 F-box protein 7
FLCN folliculin
FOXO1 forkhead box O1
FOXO3 forkhead box O3
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GPSM1 G-protein signaling modulator 1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HMGB1 high mobility group box 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL4 interleukin 4
IRGM immunity-related GTPase family, M
IRGQ immunity-related GTPase family, Q
KAT5 K(lysine) acetyltransferase 5
KDR kinase insert domain receptor
LACRT lacritin
LARP1 La ribonucleoprotein domain family, member 1
LRRK2 leucine-rich repeat kinase 2
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MEFV Mediterranean fever
MID2 midline 2
MTDH metadherin
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
OPTN optineurin
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARK7 parkinson protein 7
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PINK1 PTEN induced putative kinase 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKD1 protein kinase D1
RB1CC1 RB1-inducible coiled-coil 1
RNF152 ring finger protein 152
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RUFY4 RUN and FYVE domain containing 4
SCOC short coiled-coil protein
SESN1 sestrin 1
SESN2 sestrin 2
SESN3 sestrin 3
SETD2 SET domain containing 2
SH3BP4 SH3-domain binding protein 4
SH3GLB1 SH3-domain GRB2-like endophilin B1
SIRT1 sirtuin 1
SLC35D3 solute carrier family 35, member D3
SQSTM1 sequestosome 1
STING1 stimulator of interferon response cGAMP interactor 1
STK11 serine/threonine kinase 11
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SVIP small VCP/p97-interacting protein
TBK1 TANK-binding kinase 1
TFEB transcription factor EB
TICAM1 toll-like receptor adaptor molecule 1
TMEM59 transmembrane protein 59
TP53INP1 tumor protein p53 inducible nuclear protein 1
TPCN1 two pore segment channel 1
TRIM13 tripartite motif containing 13
TRIM21 tripartite motif containing 21
TRIM22 tripartite motif containing 22
TRIM23 tripartite motif containing 23
TRIM32 tripartite motif containing 32
TRIM65 tripartite motif containing 65
TRIM8 tripartite motif containing 8
TSC2 tuberous sclerosis 2
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UFL1 UFM1-specific ligase 1
ULK1 unc-51 like autophagy activating kinase 1
USP20 ubiquitin specific peptidase 20
WAC WW domain containing adaptor with coiled-coil
WDR24 WD repeat domain 24
XBP1 X-box binding protein 1
ZC3H12A zinc finger CCCH-type containing 12A