positive regulation of cell motility Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that activates or increases the frequency, rate or extent of cell motility. (Gene Ontology, GO_2000147)
External Link http://amigo.geneontology.org/amigo/term/GO:2000147
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Genes

250 genes participating in the positive regulation of cell motility biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACTG1 actin gamma 1
ACTN4 actinin, alpha 4
ACVR1 activin A receptor, type I
ADAM10 ADAM metallopeptidase domain 10
ADAM17 ADAM metallopeptidase domain 17
ADAM9 ADAM metallopeptidase domain 9
ADRA2A adrenoceptor alpha 2A
AIF1 allograft inflammatory factor 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ANGPTL3 angiopoietin-like 3
ARHGEF39 Rho guanine nucleotide exchange factor (GEF) 39
ATM ATM serine/threonine kinase
BCAR1 breast cancer anti-estrogen resistance 1
BMP2 bone morphogenetic protein 2
C1QTNF8 C1q and tumor necrosis factor related protein 8
CARMIL1 capping protein regulator and myosin 1 linker 1
CARMIL2 capping protein regulator and myosin 1 linker 2
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASS4 Cas scaffolding protein family member 4
CAV1 caveolin 1, caveolae protein, 22kDa
CAVIN1 caveolae associated protein 1
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CCAR1 cell division cycle and apoptosis regulator 1
CCDC25 coiled-coil domain containing 25
CCL1 chemokine (C-C motif) ligand 1
CCL11 chemokine (C-C motif) ligand 11
CCL13 chemokine (C-C motif) ligand 13
CCL14 chemokine (C-C motif) ligand 14
CCL15 chemokine (C-C motif) ligand 15
CCL16 chemokine (C-C motif) ligand 16
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CCL21 chemokine (C-C motif) ligand 21
CCL22 chemokine (C-C motif) ligand 22
CCL23 chemokine (C-C motif) ligand 23
CCL24 chemokine (C-C motif) ligand 24
CCL25 chemokine (C-C motif) ligand 25
CCL26 chemokine (C-C motif) ligand 26
CCL3 chemokine (C-C motif) ligand 3
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CCL4 chemokine (C-C motif) ligand 4
CCL4L1 chemokine (C-C motif) ligand 4-like 1
CCL5 chemokine (C-C motif) ligand 5
CCL7 chemokine (C-C motif) ligand 7
CCL8 chemokine (C-C motif) ligand 8
CCR1 chemokine (C-C motif) receptor 1
CCR7 chemokine (C-C motif) receptor 7
CD151 CD151 molecule (Raph blood group)
CDC42 cell division cycle 42
CDH13 cadherin 13
CDH5 cadherin 5, type 2 (vascular endothelium)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEMIP cell migration inducing protein, hyaluronan binding
CEP43 centrosomal protein 43
CFAP20 cilia and flagella associated protein 20
CHGA chromogranin A
CIB1 calcium and integrin binding 1 (calmyrin)
CLDN1 claudin 1
CLDN3 claudin 3
CLDN4 claudin 4
CLEC7A C-type lectin domain family 7, member A
CLSTN1 calsyntenin 1
COL1A1 collagen, type I, alpha 1
CPNE3 copine III
CREB3L4 cAMP responsive element binding protein 3-like 4
CRIPTO3 cripto, EGF-CFC family member 3
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CTSH cathepsin H
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL16 chemokine (C-X-C motif) ligand 16
CXCR4 chemokine (C-X-C motif) receptor 4
DAAM2 dishevelled associated activator of morphogenesis 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDRGK1 DDRGK domain containing 1
DRD1 dopamine receptor D1
DUOX1 dual oxidase 1
DUOX2 dual oxidase 2
DUOXA2 dual oxidase maturation factor 2
EDN1 endothelin 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ELP3 elongator acetyltransferase complex subunit 3
ELP5 elongator acetyltransferase complex subunit 5
ELP6 elongator acetyltransferase complex subunit 6
EPHA1 EPH receptor A1
EPHA2 EPH receptor A2
EPHA4 EPH receptor A4
EPHB2 EPH receptor B2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAM107A family with sequence similarity 107, member A
FAM110A family with sequence similarity 110, member A
FAM110C family with sequence similarity 110, member C
FAM89B family with sequence similarity 89, member B
FER fer (fps/fes related) tyrosine kinase
FERMT2 fermitin family member 2
FERMT3 fermitin family member 3
FGF1 fibroblast growth factor 1 (acidic)
FGR FGR proto-oncogene, Src family tyrosine kinase
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
FSHB follicle stimulating hormone, beta polypeptide
FYCO1 FYVE and coiled-coil domain containing 1
FZD4 frizzled class receptor 4
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLI1 GLI family zinc finger 1
GPER1 G protein-coupled estrogen receptor 1
GPNMB glycoprotein (transmembrane) nmb
GRB7 growth factor receptor-bound protein 7
GRN granulin
HAS2 hyaluronan synthase 2
HBEGF heparin-binding EGF-like growth factor
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGSF8 immunoglobulin superfamily, member 8
IL1B interleukin 1, beta
IL4 interleukin 4
INS insulin
INSR insulin receptor
ITGA6 integrin, alpha 6
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LAMB1 laminin, beta 1
LAMC2 laminin, gamma 2
LEF1 lymphoid enhancer-binding factor 1
LGR6 leucine-rich repeat containing G protein-coupled receptor 6
LRRC15 leucine rich repeat containing 15
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MDK midkine (neurite growth-promoting factor 2)
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MIEN1 migration and invasion enhancer 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP7 matrix metallopeptidase 7
MYADM myeloid-associated differentiation marker
MYLK myosin light chain kinase
MYO1E myosin IE
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NOTCH1 notch 1
NTF3 neurotrophin 3
NTN1 netrin 1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUMB numb homolog (Drosophila)
PDCD10 programmed cell death 10
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFC platelet derived growth factor C
PDGFD platelet derived growth factor D
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPN podoplanin
PECAM1 platelet/endothelial cell adhesion molecule 1
PHPT1 phosphohistidine phosphatase 1
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PINK1 PTEN induced putative kinase 1
PKN1 protein kinase N1
PLAU plasminogen activator, urokinase
PLET1 placenta expressed transcript 1
PODXL podocalyxin-like
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRKCA protein kinase C, alpha
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RACK1 receptor for activated C kinase 1
RDX radixin
RET ret proto-oncogene
RHOC ras homolog family member C
RHOD ras homolog family member D
RICTOR RPTOR independent companion of MTOR, complex 2
RIPOR1 RHO family interacting cell polarization regulator 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RORA RAR-related orphan receptor A
SACK1H scaffolding CK1 anchoring protein H
SDCBP syndecan binding protein (syntenin)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SH3RF2 SH3 domain containing ring finger 2
SMIM22 small integral membrane protein 22
SMOX spermine oxidase
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SOD2 superoxide dismutase 2, mitochondrial
SOS1 son of sevenless homolog 1 (Drosophila)
SPAG9 sperm associated antigen 9
SPHK1 sphingosine kinase 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPRY2 sprouty homolog 2 (Drosophila)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STX4 syntaxin 4
SUN2 Sad1 and UNC84 domain containing 2
SYNE2 spectrin repeat containing, nuclear envelope 2
SYNPO2 synaptopodin 2
TCAF2 TRPM8 channel-associated factor 2
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
THBS1 thrombospondin 1
TIAM1 T-cell lymphoma invasion and metastasis 1
TJP1 tight junction protein 1
TMSB15C thymosin beta 15C
TRADD TNFRSF1A-associated via death domain
TRIM32 tripartite motif containing 32
TRIP6 thyroid hormone receptor interactor 6
TWIST1 twist family bHLH transcription factor 1
TWIST2 twist family bHLH transcription factor 2
UBE2I ubiquitin-conjugating enzyme E2I
VEGFA vascular endothelial growth factor A
VIL1 villin 1
VSIR V-set immunoregulatory receptor
WASHC1 WASH complex subunit 1
WNT5B wingless-type MMTV integration site family, member 5B
XBP1 X-box binding protein 1
XCL1 chemokine (C motif) ligand 1
XCL2 chemokine (C motif) ligand 2
ZNF268 zinc finger protein 268
ZNF304 zinc finger protein 304
ZNF703 zinc finger protein 703