positive regulation of macromolecule metabolic process Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. (Gene Ontology, GO_0010604)
External Link http://amigo.geneontology.org/amigo/term/GO_0010604
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Genes

365 genes participating in the positive regulation of macromolecule metabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTC1 actin, alpha, cardiac muscle 1
ACTG1 actin gamma 1
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAM19 ADAM metallopeptidase domain 19
ADM2 adrenomedullin 2
ADTRP androgen-dependent TFPI-regulating protein
AFD1 acrofacial dysostosis 1, Nager type
AGR2 anterior gradient 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX12B arachidonate 12-lipoxygenase, 12R type
AMH anti-Mullerian hormone
ANGPT1 angiopoietin 1
ANK2 ankyrin 2, neuronal
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKRD31 ankyrin repeat domain 31
ANXA2 annexin A2
APP amyloid beta (A4) precursor protein
ATF2 activating transcription factor 2
ATF4 activating transcription factor 4
ATM ATM serine/threonine kinase
ATP13A2 ATPase type 13A2
AVP arginine vasopressin
AVPR2 arginine vasopressin receptor 2
AZU1 azurocidin 1
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP6 bone morphogenetic protein 6
BMP7 bone morphogenetic protein 7
BMPR1A bone morphogenetic protein receptor, type IA
BMPR1B bone morphogenetic protein receptor, type IB
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BVES blood vessel epicardial substance
C1QTNF1 C1q and tumor necrosis factor related protein 1
CALCOCO1 calcium binding and coiled-coil domain 1
CALCR calcitonin receptor
CCL3 chemokine (C-C motif) ligand 3
CD28 CD28 molecule
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD46 CD46 molecule, complement regulatory protein
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDH5 cadherin 5, type 2 (vascular endothelium)
CELF1 CUGBP, Elav-like family member 1
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLDN19 claudin 19
CLDN3 claudin 3
CLDN5 claudin 5
CLEC7A C-type lectin domain family 7, member A
CLU clusterin
CNTF ciliary neurotrophic factor
CNTN1 contactin 1
CRP C-reactive protein, pentraxin-related
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTCF CCCTC-binding factor (zinc finger protein)
CTCFL CCCTC-binding factor (zinc finger protein)-like
CTSH cathepsin H
CUX2 cut-like homeobox 2
CXCL8 chemokine (C-X-C motif) ligand 8
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDRGK1 DDRGK domain containing 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DGKQ diacylglycerol kinase, theta 110kDa
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLL1 delta-like 1 (Drosophila)
DLL4 delta-like 4 (Drosophila)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DTNBP1 dystrobrevin binding protein 1
DTX3L deltex 3 like, E3 ubiquitin ligase
E2F1 E2F transcription factor 1
ECE1 endothelin converting enzyme 1
EGF epidermal growth factor
EGR1 early growth response 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EMILIN1 elastin microfibril interfacer 1
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPHB2 EPH receptor B2
EPHX2 epoxide hydrolase 2, cytoplasmic
ERP29 endoplasmic reticulum protein 29
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EZR ezrin
FER1L6 fer-1-like family member 6
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF16 fibroblast growth factor 16
FGF17 fibroblast growth factor 17
FGF18 fibroblast growth factor 18
FGF19 fibroblast growth factor 19
FGF2 fibroblast growth factor 2 (basic)
FGF20 fibroblast growth factor 20
FGF21 fibroblast growth factor 21
FGF22 fibroblast growth factor 22
FGF23 fibroblast growth factor 23
FGF3 fibroblast growth factor 3
FGF4 fibroblast growth factor 4
FGF5 fibroblast growth factor 5
FGF6 fibroblast growth factor 6
FGF7 fibroblast growth factor 7
FGF8 fibroblast growth factor 8 (androgen-induced)
FGF9 fibroblast growth factor 9
FGFR4 fibroblast growth factor receptor 4
FN1 fibronectin 1
FOXD1 forkhead box D1
FUBP1 far upstream element (FUSE) binding protein 1
FUBP3 far upstream element (FUSE) binding protein 3
GARS1 glycyl-tRNA synthetase 1
GAS6 growth arrest-specific 6
GATA2 GATA binding protein 2
GATA5 GATA binding protein 5
GBA glucosidase, beta, acid
GCGR glucagon receptor
GJA1 gap junction protein, alpha 1, 43kDa
GPER1 G protein-coupled estrogen receptor 1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GSN gelsolin
HAND2 heart and neural crest derivatives expressed 2
HCFC1 host cell factor C1
HDAC1 histone deacetylase 1
HFE hemochromatosis
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HINFP histone H4 transcription factor
HMGA2 high mobility group AT-hook 2
HMGN5 high mobility group nucleosome binding domain 5
HOXA5 homeobox A5
HOXD3 homeobox D3
HPN hepsin
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IL13 interleukin 13
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1F10 interleukin 1 family, member 10 (theta)
IL33 interleukin 33
IL36A interleukin 36, alpha
IL36B interleukin 36, beta
IL36G interleukin 36, gamma
IL37 interleukin 37
IL4 interleukin 4
IL6 interleukin 6
INHBA inhibin, beta A
INS insulin
ITCH itchy E3 ubiquitin protein ligase
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB8 integrin, beta 8
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMP3 lysosomal-associated membrane protein 3
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
LAPTM5 lysosomal protein transmembrane 5
LEF1 lymphoid enhancer-binding factor 1
LGALS9 lectin, galactoside-binding, soluble, 9
LGALS9B lectin, galactoside-binding, soluble, 9B
LGALS9C lectin, galactoside-binding, soluble, 9C
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LIMS1 LIM and senescent cell antigen-like domains 1
LRP3 low density lipoprotein receptor-related protein 3
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MARK1 MAP/microtubule affinity-regulating kinase 1
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MBIP MAP3K12 binding inhibitory protein 1
MED1 mediator complex subunit 1
MED23 mediator complex subunit 23
MED26 mediator complex subunit 26
MEF2C myocyte enhancer factor 2C
MITF microphthalmia-associated transcription factor
MMP8 matrix metallopeptidase 8
MSN moesin
MT3 metallothionein 3
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTPN myotrophin
MUSK muscle, skeletal, receptor tyrosine kinase
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYD88 myeloid differentiation primary response 88
MYLK2 myosin light chain kinase 2
MYOM1 myomesin 1
NAT8 N-acetyltransferase 8 (GCN5-related, putative)
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)
NFE2L2 nuclear factor, erythroid 2-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGF nerve growth factor (beta polypeptide)
NKX2-1 NK2 homeobox 1
NKX3-1 NK3 homeobox 1
NOG noggin
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR5A1 nuclear receptor subfamily 5, group A, member 1
NSF N-ethylmaleimide-sensitive factor
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NTS neurotensin
NTSR1 neurotensin receptor 1 (high affinity)
NWD1 NACHT and WD repeat domain containing 1
OCLN occludin
OCRL oculocerebrorenal syndrome of Lowe
ODAM odontogenic, ameloblast asssociated
OLFM1 olfactomedin 1
OSR2 odd-skipped related transciption factor 2
OVOL2 ovo-like zinc finger 2
OXSR1 oxidative stress responsive 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PAX6 paired box 6
PDCD10 programmed cell death 10
PDCD5 programmed cell death 5
PDCL3 phosducin-like 3
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDGFB platelet-derived growth factor beta polypeptide
PF4 platelet factor 4
PGR progesterone receptor
PHB prohibitin
PID1 phosphotyrosine interaction domain containing 1
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIP prolactin-induced protein
PKP1 plakophilin 1
PKP3 plakophilin 3
PLA2G10 phospholipase A2, group X
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLSCR1 phospholipid scramblase 1
POU3F1 POU class 3 homeobox 1
POU3F3 POU class 3 homeobox 3
POU4F1 POU class 4 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PSEN1 presenilin 1
PSG1 pregnancy specific beta-1-glycoprotein 1
PSG4 pregnancy specific beta-1-glycoprotein 4
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAB27A RAB27A, member RAS oncogene family
RAB29 RAB29, member RAS oncogene family
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RAMP3 receptor (G protein-coupled) activity modifying protein 3
RBMS3 RNA binding motif, single stranded interacting protein 3
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RDX radixin
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGCC regulator of cell cycle
RHOXF1 Rhox homeobox family, member 1
RHOXF2 Rhox homeobox family, member 2
RHOXF2B Rhox homeobox family, member 2B
RIMS1 regulating synaptic membrane exocytosis 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RLN2 relaxin 2
RNF207 ring finger protein 207
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPL11 ribosomal protein L11
RPL17 ribosomal protein L17
RPL5 ribosomal protein L5
RPS3 ribosomal protein S3
RPS7 ribosomal protein S7
SCRIB scribbled planar cell polarity protein
SCX scleraxis basic helix-loop-helix transcription factor
SEC16B SEC16 homolog B (S. cerevisiae)
SFRP4 secreted frizzled-related protein 4
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC26A9 solute carrier family 26 (anion exchanger), member 9
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC38A2 solute carrier family 38, member 2
SMAD3 SMAD family member 3
SMO smoothened, frizzled class receptor
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNF8 SNF8, ESCRT-II complex subunit
SOX11 SRY (sex determining region Y)-box 11
SOX9 SRY (sex determining region Y)-box 9
SPRY2 sprouty homolog 2 (Drosophila)
SRPK2 SRSF protein kinase 2
SRY sex determining region Y
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STOX1 storkhead box 1
TADA3 transcriptional adaptor 3
TCF23 transcription factor 23
TERF2 telomeric repeat binding factor 2
TESC tescalcin
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TICAM1 toll-like receptor adaptor molecule 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLR9 toll-like receptor 9
TMEM119 transmembrane protein 119
TNC tenascin C
TNF tumor necrosis factor
TP53 tumor protein p53
TRAPPC2B trafficking protein particle complex 2B
TREM2 triggering receptor expressed on myeloid cells 2
TSLIG3A tRNA splicing ligase complex subunit 3A
TSLIG3B tRNA splicing ligase complex subunit 3B
TTBK1 tau tubulin kinase 1
TTN titin
TWIST1 twist family bHLH transcription factor 1
TYROBP TYRO protein tyrosine kinase binding protein
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UHRF1 ubiquitin-like with PHD and ring finger domains 1
UXT ubiquitously-expressed, prefoldin-like chaperone
VAMP3 vesicle-associated membrane protein 3
VEGFA vascular endothelial growth factor A
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
VSIR V-set immunoregulatory receptor
VSTM2A V-set and transmembrane domain containing 2A
WARS1 tryptophanyl-tRNA synthetase 1
WFS1 Wolfram syndrome 1 (wolframin)
WNT16 wingless-type MMTV integration site family, member 16
WNT3 wingless-type MMTV integration site family, member 3
WNT3A wingless-type MMTV integration site family, member 3A
WNT5A wingless-type MMTV integration site family, member 5A
WNT6 wingless-type MMTV integration site family, member 6
WNT7A wingless-type MMTV integration site family, member 7A
WT1 Wilms tumor 1
YAP1 Yes-associated protein 1
ZBTB7B zinc finger and BTB domain containing 7B
ZC3H12A zinc finger CCCH-type containing 12A
ZNF580 zinc finger protein 580
ZNF804A zinc finger protein 804A
ZPR1 ZPR1 zinc finger