positive regulation of programmed cell death Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. (Gene Ontology, GO_0043068)
External Link http://amigo.geneontology.org/amigo/term/GO_0043068
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Genes

246 genes participating in the positive regulation of programmed cell death biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACVR1C activin A receptor, type IC
ADAMTSL4 ADAMTS-like 4
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ANO6 anoctamin 6
APAF1 apoptotic peptidase activating factor 1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APC adenomatous polyposis coli
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ATF4 activating transcription factor 4
ATF6 activating transcription factor 6
ATG7 autophagy related 7
ATM ATM serine/threonine kinase
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BARD1 BRCA1 associated RING domain 1
BAX BCL2-associated X protein
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL6 B-cell CLL/lymphoma 6
BCLAF1 BCL2-associated transcription factor 1
BID BH3 interacting domain death agonist
BIN1 bridging integrator 1
BMF Bcl2 modifying factor
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BOK BCL2-related ovarian killer
C1QBP complement component 1, q subcomponent binding protein
C3ORF38 chromosome 3 open reading frame 38
CALHM2 calcium homeostasis modulator 2
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCAR1 cell division cycle and apoptosis regulator 1
CCAR2 cell cycle and apoptosis regulator 2
CFLAR CASP8 and FADD-like apoptosis regulator
CLEC7A C-type lectin domain family 7, member A
CLIP3 CAP-GLY domain containing linker protein 3
CLU clusterin
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CSRNP3 cysteine-serine-rich nuclear protein 3
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNNBL1 catenin, beta like 1
CTSD cathepsin D
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAB2IP DAB2 interacting protein
DAPK1 death-associated protein kinase 1
DAPK2 death-associated protein kinase 2
DAPK3 death-associated protein kinase 3
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DIABLO diablo, IAP-binding mitochondrial protein
DKKL1 dickkopf-like 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNM1L dynamin 1-like
DNM2 dynamin 2
DUSP6 dual specificity phosphatase 6
E2F1 E2F transcription factor 1
ECT2 epithelial cell transforming 2
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EMILIN1 elastin microfibril interfacer 1
EMILIN2 elastin microfibril interfacer 2
ERCC3 excision repair cross-complementation group 3
FADD Fas (TNFRSF6)-associated via death domain
FAF1 Fas (TNFRSF6) associated factor 1
FAM162A family with sequence similarity 162, member A
FANK1 fibronectin type III and ankyrin repeat domains 1
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FLCN folliculin
FOXA1 forkhead box A1
FOXL2 forkhead box L2
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FRZB frizzled-related protein
FZD9 frizzled class receptor 9
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
GBP1 guanylate binding protein 1, interferon-inducible
GBP2 guanylate binding protein 2, interferon-inducible
GBP3 guanylate binding protein 3
GBP5 guanylate binding protein 5
GPER1 G protein-coupled estrogen receptor 1
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HDAC6 histone deacetylase 6
HIP1R huntingtin interacting protein 1 related
HMGB1 high mobility group box 1
HOXA5 homeobox A5
HRK harakiri, BCL2 interacting protein
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
HTRA1 HtrA serine peptidase 1
HTRA2 HtrA serine peptidase 2
HTRA4 HtrA serine peptidase 4
HTT huntingtin
IAPP islet amyloid polypeptide
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNG interferon, gamma
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
IL6 interleukin 6
ING4 inhibitor of growth family, member 4
ING5 inhibitor of growth family, member 5
IP6K2 inositol hexakisphosphate kinase 2
IRF5 interferon regulatory factor 5
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JMY junction mediating and regulatory protein, p53 cofactor
JUN jun proto-oncogene
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KLF11 Kruppel-like factor 11
KNG1 kininogen 1
LAPTM5 lysosomal protein transmembrane 5
LATS1 large tumor suppressor kinase 1
LATS2 large tumor suppressor kinase 2
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS2 lectin, galactoside-binding, soluble, 2
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LRRK2 leucine-rich repeat kinase 2
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K20 mitogen-activated protein kinase kinase kinase 20
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK8 mitogen-activated protein kinase 8
MARK4 MAP/microtubule affinity-regulating kinase 4
MCL1 myeloid cell leukemia 1
MELK maternal embryonic leucine zipper kinase
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MNDA myeloid cell nuclear differentiation antigen
MOAP1 modulator of apoptosis 1
MTCH1 mitochondrial carrier 1
MTCH2 mitochondrial carrier 2
NEURL1 neuralized E3 ubiquitin protein ligase 1
NEUROD1 neuronal differentiation 1
NF1 neurofibromin 1
NLRC4 NLR family, CARD domain containing 4
NLRP2P NLR family, pyrin domain containing 2 pseudogene
NOS2 nitric oxide synthase 2, inducible
NRG1 neuregulin 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OLFM1 olfactomedin 1
OMA1 OMA1 zinc metallopeptidase
PANO1 proapoptotic nucleolar protein 1
PAWR PRKC, apoptosis, WT1, regulator
PDCD2 programmed cell death 2
PDCD5 programmed cell death 5
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIDD1 p53-induced death domain protein 1
PIP5KL1 phosphatidylinositol-4-phosphate 5-kinase-like 1
PLEKHN1 pleckstrin homology domain containing, family N member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PNMA1 paraneoplastic Ma antigen 1
PNMA2 paraneoplastic Ma antigen 2
PNMA3 paraneoplastic Ma antigen 3
PNMA5 paraneoplastic Ma antigen family member 5
POU4F2 POU class 4 homeobox 2
PPID peptidylprolyl isomerase D
PRF1 perforin 1 (pore forming protein)
PRMT2 protein arginine methyltransferase 2
PRR7 proline rich 7 (synaptic)
PTPA protein phosphatase 2 phosphatase activator
PXT1 peroxisomal, testis specific 1
PYCARD PYD and CARD domain containing
QRICH1 glutamine-rich 1
RACK1 receptor for activated C kinase 1
RARG retinoic acid receptor, gamma
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBM5 RNA binding motif protein 5
REST RE1-silencing transcription factor
RFPL1 ret finger protein-like 1
RHOB ras homolog family member B
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF122 ring finger protein 122
RNPS1 RNA binding protein S1, serine-rich domain
RPS6 ribosomal protein S6
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RRP1B ribosomal RNA processing 1B
RYBP RING1 and YY1 binding protein
SAP18 Sin3A-associated protein, 18kDa
SAV1 salvador family WW domain containing protein 1
SCIN scinderin
SCRIB scribbled planar cell polarity protein
SEPTIN4 septin 4
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SFRP4 secreted frizzled-related protein 4
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor
SIAH1 siah E3 ubiquitin protein ligase 1
SIRT1 sirtuin 1
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLIT2 slit homolog 2 (Drosophila)
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SOX4 SRY (sex determining region Y)-box 4
SPDEF SAM pointed domain containing ETS transcription factor
SPHK2 sphingosine kinase 2
SQSTM1 sequestosome 1
STK17A serine/threonine kinase 17a
STK17B serine/threonine kinase 17b
STK3 serine/threonine kinase 3
STK4 serine/threonine kinase 4
STPG1 sperm-tail PG-rich repeat containing 1
SYK spleen tyrosine kinase
TCTN3 tectonic family member 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
TGFB3 transforming growth factor, beta 3
TGM2 transglutaminase 2
TMEM164 transmembrane protein 164
TNF tumor necrosis factor
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TRADD TNFRSF1A-associated via death domain
TRIM35 tripartite motif containing 35
UBD ubiquitin D
UBE2Z ubiquitin-conjugating enzyme E2Z
UNC13B unc-13 homolog B (C. elegans)
USP27X ubiquitin specific peptidase 27, X-linked
UTP11 UTP11 small subunit processome component
WNT10B wingless-type MMTV integration site family, member 10B
ZNF268 zinc finger protein 268
ZNF622 zinc finger protein 622