positive regulation of proteasomal ubiquitin-dependent protein catabolic process Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. (Gene Ontology, GO_0032436)
External Link http://amigo.geneontology.org/amigo/term/GO_0032436
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Genes

84 genes participating in the positive regulation of proteasomal ubiquitin-dependent protein catabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANKIB1 ankyrin repeat and IBR domain containing 1
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
AXIN1 axin 1
AXIN2 axin 2
BAG2 BCL2-associated athanogene 2
BBS7 Bardet-Biedl syndrome 7
BCAP31 B-cell receptor-associated protein 31
CAV1 caveolin 1, caveolae protein, 22kDa
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CDC20 cell division cycle 20
CDC20B cell division cycle 20B
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLU clusterin
COP1 COP1 E3 ubiquitin ligase
CSNK1A1 casein kinase 1, alpha 1
CSNK1D casein kinase 1, delta
CSNK1E casein kinase 1, epsilon
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDA1 DET1 and DDB1 associated 1
DDRGK1 DDRGK domain containing 1
DET1 de-etiolated homolog 1 (Arabidopsis)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DVL1 dishevelled segment polarity protein 1
ELOB elongin B
FBXO22 F-box protein 22
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABARAP GABA(A) receptor-associated protein
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
KEAP1 kelch-like ECH-associated protein 1
KLHL40 kelch-like family member 40
LRRK2 leucine-rich repeat kinase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
NFE2L2 nuclear factor, erythroid 2-like 2
NKD2 naked cuticle homolog 2 (Drosophila)
NOP53 NOP53 ribosome biogenesis factor
NUB1 negative regulator of ubiquitin-like proteins 1
PABIR1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PIAS1 protein inhibitor of activated STAT, 1
PLK1 polo-like kinase 1
PLK3 polo-like kinase 3
PRICKLE1 prickle homolog 1 (Drosophila)
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
RACK1 receptor for activated C kinase 1
RAD23A RAD23 homolog A (S. cerevisiae)
RBX1 ring-box 1, E3 ubiquitin protein ligase
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RFPL1 ret finger protein-like 1
RNF14 ring finger protein 14
RNF144A ring finger protein 144A
RNF144B ring finger protein 144B
RNF180 ring finger protein 180
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF19B ring finger protein 19B
RNF217 ring finger protein 217
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH3RF1 SH3 domain containing ring finger 1
SH3RF2 SH3 domain containing ring finger 2
SH3RF3 SH3 domain containing ring finger 3
SIRT2 sirtuin 2
SIRT6 sirtuin 6
SMAD7 SMAD family member 7
SOCS5 suppressor of cytokine signaling 5
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TRIB1 tribbles pseudokinase 1
TRIB2 tribbles pseudokinase 2
TRIB3 tribbles pseudokinase 3
UBQLN1 ubiquilin 1
UBQLN2 ubiquilin 2
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VCP valosin containing protein
ZER1 zyg-11 related, cell cycle regulator
ZYG11B zyg-11 family member B, cell cycle regulator