positive regulation of proteolysis Gene Set

Dataset GO Biological Process Annotations 2015
Category structural or functional annotations
Type biological process
Description Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. (Gene Ontology, GO_0045862)
External Link http://amigo.geneontology.org/amigo/term/GO:0045862
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Genes

307 genes participating in the positive regulation of proteolysis biological process from the curated GO Biological Process Annotations 2015 dataset.

Symbol Name
ACER2 alkaline ceramidase 2
ACVR1C activin A receptor, type IC
ADAM8 ADAM metallopeptidase domain 8
ADAM9 ADAM metallopeptidase domain 9
ADRA2A adrenoceptor alpha 2A
ADRM1 adhesion regulating molecule 1
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AIM2 absent in melanoma 2
AKIRIN2 akirin 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX12 arachidonate 12-lipoxygenase
ANAPC1 anaphase promoting complex subunit 1
ANAPC10 anaphase promoting complex subunit 10
ANAPC11 anaphase promoting complex subunit 11
ANAPC2 anaphase promoting complex subunit 2
ANAPC4 anaphase promoting complex subunit 4
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
APAF1 apoptotic peptidase activating factor 1
APOE apolipoprotein E
APOPT1 apoptogenic 1, mitochondrial
APP amyloid beta (A4) precursor protein
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ASPH aspartate beta-hydroxylase
ATPIF1 ATPase inhibitory factor 1
AURKA aurora kinase A
AURKAIP1 aurora kinase A interacting protein 1
AXIN1 axin 1
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BBS7 Bardet-Biedl syndrome 7
BCAP31 B-cell receptor-associated protein 31
BCL10 B-cell CLL/lymphoma 10
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BID BH3 interacting domain death agonist
BOK BCL2-related ovarian killer
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CAPN3 calpain 3, (p94)
CARD8 caspase recruitment domain family, member 8
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP14 caspase 14, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP8AP2 caspase 8 associated protein 2
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CAV3 caveolin 3
CCDC22 coiled-coil domain containing 22
CCK cholecystokinin
CCNB1 cyclin B1
CDC16 cell division cycle 16
CDC20 cell division cycle 20
CDC23 cell division cycle 23
CDC26 cell division cycle 26
CDC27 cell division cycle 27
CDK1 cyclin-dependent kinase 1
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFLAR CASP8 and FADD-like apoptosis regulator
CIDEB cell death-inducing DFFA-like effector b
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CLU clusterin
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CSNK1D casein kinase 1, delta
CTGF connective tissue growth factor
CTSC cathepsin C
CTSH cathepsin H
CUL1 cullin 1
CUL3 cullin 3
CYCS cytochrome c, somatic
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYR61 cysteine-rich, angiogenic inducer, 61
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAB2IP DAB2 interacting protein
DAP death-associated protein
DAPK1 death-associated protein kinase 1
DDRGK1 DDRGK domain containing 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DIABLO diablo, IAP-binding mitochondrial protein
DISC1 disrupted in schizophrenia 1
DLC1 DLC1 Rho GTPase activating protein
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DTHD1 death domain containing 1
DVL1 dishevelled segment polarity protein 1
EGF epidermal growth factor
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FADD Fas (TNFRSF6)-associated via death domain
FAM162A family with sequence similarity 162, member A
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBLN1 fibulin 1
FBXO22 F-box protein 22
FBXO5 F-box protein 5
FBXW11 F-box and WD repeat domain containing 11
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGFR4 fibroblast growth factor receptor 4
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FN1 fibronectin 1
FOXL2 forkhead box L2
FURIN furin (paired basic amino acid cleaving enzyme)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GBA glucosidase, beta, acid
GCLC glutamate-cysteine ligase, catalytic subunit
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPER1 G protein-coupled estrogen receptor 1
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GSK3B glycogen synthase kinase 3 beta
GSN gelsolin
HDAC2 histone deacetylase 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIP1 huntingtin interacting protein 1
HMGB1 high mobility group box 1
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
HTRA2 HtrA serine peptidase 2
IFI16 interferon, gamma-inducible protein 16
IFI27 interferon, alpha-inducible protein 27
IFNG interferon, gamma
IFT57 intraflagellar transport 57
IL1B interleukin 1, beta
IL24 interleukin 24
IL33 interleukin 33
IST1 increased sodium tolerance 1 homolog (yeast)
JAK2 Janus kinase 2
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KEAP1 kelch-like ECH-associated protein 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LRRK2 leucine-rich repeat kinase 2
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK12 mitogen-activated protein kinase 12
MAPK9 mitogen-activated protein kinase 9
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEFV Mediterranean fever
MEN1 multiple endocrine neoplasia I
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MTCH1 mitochondrial carrier 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NEK5 NIMA-related kinase 5
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NKD2 naked cuticle homolog 2 (Drosophila)
NKX3-1 NK3 homeobox 1
NLRC4 NLR family, CARD domain containing 4
NLRP1 NLR family, pyrin domain containing 1
NLRP12 NLR family, pyrin domain containing 12
NLRP2 NLR family, pyrin domain containing 2
NLRP3 NLR family, pyrin domain containing 3
NOD1 nucleotide-binding oligomerization domain containing 1
NODAL nodal growth differentiation factor
NRD1 nardilysin (N-arginine dibasic convertase)
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
NUB1 negative regulator of ubiquitin-like proteins 1
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OSBPL7 oxysterol binding protein-like 7
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PARK2 parkin RBR E3 ubiquitin protein ligase
PCOLCE procollagen C-endopeptidase enhancer
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDCD2 programmed cell death 2
PDCD5 programmed cell death 5
PDCD6 programmed cell death 6
PERP PERP, TP53 apoptosis effector
PIAS1 protein inhibitor of activated STAT, 1
PICALM phosphatidylinositol binding clathrin assembly protein
PIDD1 p53-induced death domain protein 1
PINK1 PTEN induced putative kinase 1
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PPARG peroxisome proliferator-activated receptor gamma
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PRELID1 PRELI domain containing 1
PRICKLE1 prickle homolog 1 (Drosophila)
PSEN1 presenilin 1
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSME4 proteasome (prosome, macropain) activator subunit 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PYCARD PYD and CARD domain containing
RB1 retinoblastoma 1
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
REST RE1-silencing transcription factor
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF139 ring finger protein 139
RNF180 ring finger protein 180
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS27A ribosomal protein S27a
RPS27L ribosomal protein S27-like
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SENP1 SUMO1/sentrin specific peptidase 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SFRP2 secreted frizzled-related protein 2
SH3D19 SH3 domain containing 19
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SKP1 S-phase kinase-associated protein 1
SMAD3 SMAD family member 3
SMAD7 SMAD family member 7
SMC5 structural maintenance of chromosomes 5
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX33 sorting nexin 33
SNX9 sorting nexin 9
SOCS4 suppressor of cytokine signaling 4
SOCS5 suppressor of cytokine signaling 5
SOX7 SRY (sex determining region Y)-box 7
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBC1D10A TBC1 domain family, member 10A
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRADD TNFRSF1A-associated via death domain
TRAF2 TNF receptor-associated factor 2
TRIB1 tribbles pseudokinase 1
TRIB2 tribbles pseudokinase 2
TRIB3 tribbles pseudokinase 3
TRIM32 tripartite motif containing 32
TRIM67 tripartite motif containing 67
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2C ubiquitin-conjugating enzyme E2C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VCP valosin containing protein
WFS1 Wolfram syndrome 1 (wolframin)
WNT3A wingless-type MMTV integration site family, member 3A
XBP1 X-box binding protein 1
XDH xanthine dehydrogenase
ZFAND2A zinc finger, AN1-type domain 2A