positive regulation of synaptic transmission Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. (Gene Ontology, GO_0050806)
External Link http://amigo.geneontology.org/amigo/term/GO:0050806
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Genes

85 genes participating in the positive regulation of synaptic transmission biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADCY1 adenylate cyclase 1 (brain)
ADCY8 adenylate cyclase 8 (brain)
ADRA1A adrenoceptor alpha 1A
AGER advanced glycosylation end product-specific receptor
AKAP5 A kinase (PRKA) anchor protein 5
APP amyloid beta (A4) precursor protein
ARC activity-regulated cytoskeleton-associated protein
BAIAP3 BAI1-associated protein 3
BGLAP bone gamma-carboxyglutamate (gla) protein
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CACNG3 calcium channel, voltage-dependent, gamma subunit 3
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CACNG7 calcium channel, voltage-dependent, gamma subunit 7
CACNG8 calcium channel, voltage-dependent, gamma subunit 8
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCL2 chemokine (C-C motif) ligand 2
CCR2 chemokine (C-C motif) receptor 2
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
CLSTN1 calsyntenin 1
CLSTN2 calsyntenin 2
CLSTN3 calsyntenin 3
CRHR2 corticotropin releasing hormone receptor 2
DRD1 dopamine receptor D1
DTNBP1 dystrobrevin binding protein 1
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EPHB2 EPH receptor B2
FLOT1 flotillin 1
FMR1 fragile X mental retardation 1
GPER1 G protein-coupled estrogen receptor 1
GPR158 G protein-coupled receptor 158
GPRIN1 G protein regulated inducer of neurite outgrowth 1
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
HAP1 huntingtin-associated protein 1
INS insulin
KCTD13 potassium channel tetramerization domain containing 13
LGI1 leucine-rich, glioma inactivated 1
LGMN legumain
LLGL1 lethal giant larvae homolog 1 (Drosophila)
MICU3 mitochondrial calcium uptake family, member 3
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
NALCN sodium leak channel, non selective
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NLGN1 neuroligin 1
NLGN2 neuroligin 2
NLGN3 neuroligin 3
NMU neuromedin U
NPS neuropeptide S
NPTN neuroplastin
NRXN1 neurexin 1
PLK2 polo-like kinase 2
PRKCZ protein kinase C, zeta
PTK2B protein tyrosine kinase 2 beta
RAPSN receptor-associated protein of the synapse
RELN reelin
RGS14 regulator of G-protein signaling 14
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHANK3 SH3 and multiple ankyrin repeat domains 3
SHISA7 shisa family member 7
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SQSTM1 sequestosome 1
STX1B syntaxin 1B
STX4 syntaxin 4
SYT1 synaptotagmin I
TNF tumor necrosis factor
TSHZ3 teashirt zinc finger homeobox 3
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
ZDHHC12 zinc finger, DHHC-type containing 12
ZDHHC2 zinc finger, DHHC-type containing 2
ZDHHC3 zinc finger, DHHC-type containing 3