positivity Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

195 genes co-occuring with the biological term positivity in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AANAT aralkylamine N-acetyltransferase
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADRB1 adrenoceptor beta 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALK anaplastic lymphoma receptor tyrosine kinase
AMACR alpha-methylacyl-CoA racemase
APOH apolipoprotein H (beta-2-glycoprotein I)
AR androgen receptor
BAG1 BCL2-associated athanogene
BAG3 BCL2-associated athanogene 3
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
C4B complement component 4B (Chido blood group)
CALB2 calbindin 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCNB1 cyclin B1
CCND1 cyclin D1
CCNE1 cyclin E1
CD1A CD1a molecule
CD24 CD24 molecule
CD34 CD34 molecule
CD44 CD44 molecule (Indian blood group)
CD99 CD99 molecule
CDC73 cell division cycle 73
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX2 caudal type homeobox 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLDN1 claudin 1
CLDN18 claudin 18
CLDN7 claudin 7
CRLS1 cardiolipin synthase 1
CRP C-reactive protein, pentraxin-related
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCR3 chemokine (C-X-C motif) receptor 3
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DRD2 dopamine receptor D2
EBF3 early B-cell factor 3
ECD ecdysoneless homolog (Drosophila)
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ENAH enabled homolog (Drosophila)
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EZR ezrin
F2R coagulation factor II (thrombin) receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCRL4 Fc receptor-like 4
FGFR2 fibroblast growth factor receptor 2
FLT3 fms-related tyrosine kinase 3
FMR1 fragile X mental retardation 1
FN1 fibronectin 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GATA3 GATA binding protein 3
GCG glucagon
GDF3 growth differentiation factor 3
GNAS GNAS complex locus
GPC3 glypican 3
GSTM1 glutathione S-transferase mu 1
HBG2 hemoglobin, gamma G
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
ICAM1 intercellular adhesion molecule 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IKZF4 IKAROS family zinc finger 4 (Eos)
IL1RN interleukin 1 receptor antagonist
IL2RA interleukin 2 receptor, alpha
IL5RA interleukin 5 receptor, alpha
ILK integrin-linked kinase
INS insulin
IRX1 iroquois homeobox 1
JAK2 Janus kinase 2
JAKMIP2 janus kinase and microtubule interacting protein 2
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK6 kallikrein-related peptidase 6
KRT19 keratin 19, type I
KRT20 keratin 20, type I
KRT5 keratin 5, type II
KRT7 keratin 7, type II
LCN2 lipocalin 2
LGALS3 lectin, galactoside-binding, soluble, 3
LHX1 LIM homeobox 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAGEC1 melanoma antigen family C1
MAPT microtubule-associated protein tau
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEFV Mediterranean fever
MET MET proto-oncogene, receptor tyrosine kinase
MICA MHC class I polypeptide-related sequence A
MIR205 microRNA 205
MIR21 microRNA 21
MKI67 marker of proliferation Ki-67
MME membrane metallo-endopeptidase
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MSLN mesothelin
MTA1 metastasis associated 1
MTNR1A melatonin receptor 1A
MUC1 mucin 1, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NAPSA napsin A aspartic peptidase
NCAM1 neural cell adhesion molecule 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKX2-1 NK2 homeobox 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NR1H4 nuclear receptor subfamily 1, group H, member 4
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PARP1 poly (ADP-ribose) polymerase 1
PDCD1 programmed cell death 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDPN podoplanin
PGF placental growth factor
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLAUR plasminogen activator, urokinase receptor
PLK1 polo-like kinase 1
PPARG peroxisome proliferator-activated receptor gamma
PRLR prolactin receptor
PRMT2 protein arginine methyltransferase 2
PROM1 prominin 1
PRRT2 proline-rich transmembrane protein 2
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RETN resistin
RHOA ras homolog family member A
RPH3A rabphilin 3A
SALL4 spalt-like transcription factor 4
SELL selectin L
SEPT9 septin 9
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SKOR2 SKI family transcriptional corepressor 2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC25A27 solute carrier family 25, member 27
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSTR2 somatostatin receptor 2
SSTR4 somatostatin receptor 4
SSTR5 somatostatin receptor 5
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TCL1A T-cell leukemia/lymphoma 1A
TERT telomerase reverse transcriptase
TF transferrin
TFRC transferrin receptor
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TJP1 tight junction protein 1
TLR4 toll-like receptor 4
TMPRSS4 transmembrane protease, serine 4
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TP63 tumor protein p63
TPO thyroid peroxidase
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
UGT1A UDP glucuronosyltransferase 1 family, polypeptide A complex locus
VEGFA vascular endothelial growth factor A
WISP2 WNT1 inducible signaling pathway protein 2
WT1 Wilms tumor 1