postsynaptic density Gene Set

Dataset GO Cellular Component Annotations 2023
Category structural or functional annotations
Type biological process
Description The postsynaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases. The postsynaptic density may be part of a neuron or a muscle cell or a glial cell. (Gene Ontology, GO_0014069)
External Link http://amigo.geneontology.org/amigo/term/GO:0014069
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152 proteins localized to the postsynaptic density cellular component from the curated GO Cellular Component Annotations 2023 dataset.

Symbol Name
ABI3 ABI family, member 3
ADCY8 adenylate cyclase 8 (brain)
ADD1 adducin 1 (alpha)
ADD2 adducin 2 (beta)
ADD3 adducin 3 (gamma)
ADGRA1 adhesion G protein-coupled receptor A1
ADGRB1 adhesion G protein-coupled receptor B1
ADGRL1 adhesion G protein-coupled receptor L1
AKAP5 A kinase (PRKA) anchor protein 5
ARHGAP32 Rho GTPase activating protein 32
ARHGAP44 Rho GTPase activating protein 44
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
C15ORF59 chromosome 15 open reading frame 59
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CACNG3 calcium channel, voltage-dependent, gamma subunit 3
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CACNG7 calcium channel, voltage-dependent, gamma subunit 7
CACNG8 calcium channel, voltage-dependent, gamma subunit 8
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CNIH4 cornichon family AMPA receptor auxiliary protein 4
CPEB4 cytoplasmic polyadenylation element binding protein 4
CRIPT cysteine-rich PDZ-binding protein
CTNND2 catenin (cadherin-associated protein), delta 2
DAGLA diacylglycerol lipase, alpha
DISC1 disrupted in schizophrenia 1
DLG1 discs, large homolog 1 (Drosophila)
DLG2 discs, large homolog 2 (Drosophila)
DLG3 discs, large homolog 3 (Drosophila)
DLG4 discs, large homolog 4 (Drosophila)
DLG5 discs, large homolog 5 (Drosophila)
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNM3 dynamin 3
DTNB dystrobrevin, beta
DTNBP1 dystrobrevin binding protein 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM196A family with sequence similarity 196, member A
FAM196B family with sequence similarity 196, member B
FMR1 fragile X mental retardation 1
FOXM1 forkhead box M1
FXR1 fragile X mental retardation, autosomal homolog 1
FXR2 fragile X mental retardation, autosomal homolog 2
FYN FYN proto-oncogene, Src family tyrosine kinase
GAP43 growth associated protein 43
GPER1 G protein-coupled estrogen receptor 1
GPHN gephyrin
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRID1 glutamate receptor, ionotropic, delta 1
GRID2 glutamate receptor, ionotropic, delta 2
GRIK1 glutamate receptor, ionotropic, kainate 1
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIK3 glutamate receptor, ionotropic, kainate 3
GRIK4 glutamate receptor, ionotropic, kainate 4
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
GRM1 glutamate receptor, metabotropic 1
GRM5 glutamate receptor, metabotropic 5
HIP1R huntingtin interacting protein 1 related
HOMER1 homer scaffolding protein 1
HOMER2 homer scaffolding protein 2
HOMER3 homer scaffolding protein 3
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IQSEC3 IQ motif and Sec7 domain 3
KALRN kalirin, RhoGEF kinase
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
LPPR4 lipid phosphate phosphatase-related protein type 4
LRP4 low density lipoprotein receptor-related protein 4
LRRC7 leucine rich repeat containing 7
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MTMR2 myotubularin related protein 2
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NEURL1 neuralized E3 ubiquitin protein ligase 1
NLGN1 neuroligin 1
NOS1 nitric oxide synthase 1 (neuronal)
NSF N-ethylmaleimide-sensitive factor
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PDLIM5 PDZ and LIM domain 5
PICK1 protein interacting with PRKCA 1
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PRNP prion protein
PTK2B protein tyrosine kinase 2 beta
PTPRS protein tyrosine phosphatase, receptor type, S
RGS14 regulator of G-protein signaling 14
RHEBP1 Ras-homolog enriched in brain pseudogene 1
RNF112 ring finger protein 112
RPL12 ribosomal protein L12
RPL14 ribosomal protein L14
RPL30 ribosomal protein L30
RPL38 ribosomal protein L38
RPL7 ribosomal protein L7
RPL8 ribosomal protein L8
RPLP0 ribosomal protein, large, P0
RPS13 ribosomal protein S13
RPS14 ribosomal protein S14
RPS18 ribosomal protein S18
RPS19 ribosomal protein S19
RPS25 ribosomal protein S25
RPS27 ribosomal protein S27
RPS3 ribosomal protein S3
RTN1 reticulon 1
RTN3 reticulon 3
RTN4 reticulon 4
S100G S100 calcium binding protein G
SAMD14 sterile alpha motif domain containing 14
SCRIB scribbled planar cell polarity protein
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SH2D5 SH2 domain containing 5
SHANK1 SH3 and multiple ankyrin repeat domains 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHANK3 SH3 and multiple ankyrin repeat domains 3
SHISA6 shisa family member 6
SHISA7 shisa family member 7
SHISA8 shisa family member 8
SHISA9 shisa family member 9
SIGMAR1 sigma non-opioid intracellular receptor 1
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRCIN1 SRC kinase signaling inhibitor 1
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
STRN striatin, calmodulin binding protein
SYNDIG1 synapse differentiation inducing 1
SYT11 synaptotagmin XI
TMEM108 transmembrane protein 108
TSC2 tuberous sclerosis 2
USP50 ubiquitin specific peptidase 50
USP8 ubiquitin specific peptidase 8
ZDHHC2 zinc finger, DHHC-type containing 2