postsynaptic density Gene Set

Dataset SynGO Synaptic Gene Annotations
Category structural or functional annotations
Type biological term
Description The postsynaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases. The postsynaptic density may be part of a neuron or a muscle cell or a glial cell. (Gene Ontology, GO_0014069)
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Genes

162 genes associated with the synaptic term postsynaptic density from the SynGO Synaptic Gene Annotations dataset.

Symbol Name
ABI1 abl-interactor 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABLIM1 actin binding LIM protein 1
ADGRA1 adhesion G protein-coupled receptor A1
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
AMOT angiomotin
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARF1 ADP-ribosylation factor 1
ARHGAP32 Rho GTPase activating protein 32
ARHGAP33 Rho GTPase activating protein 33
ARHGAP44 Rho GTPase activating protein 44
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
AURKA aurora kinase A
BAIAP2 BAI1-associated protein 2
BRSK1 BR serine/threonine kinase 1
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAPN1 calpain 1, (mu/I) large subunit
CAPZB capping protein (actin filament) muscle Z-line, beta
CASP3 caspase 3, apoptosis-related cysteine peptidase
CD200 CD200 molecule
CHMP2B charged multivesicular body protein 2B
CHMP4A charged multivesicular body protein 4A
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRTAC1 cartilage acidic protein 1
CRTC1 CREB regulated transcription coactivator 1
CTNND2 catenin (cadherin-associated protein), delta 2
CYLD cylindromatosis (turban tumor syndrome)
DAPK1 death-associated protein kinase 1
DBN1 drebrin 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DGCR8 DGCR8 microprocessor complex subunit
DGKZ diacylglycerol kinase, zeta
DISC1 disrupted in schizophrenia 1
DLG5 discs, large homolog 5 (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DPYSL2 dihydropyrimidinase-like 2
DROSHA drosha, ribonuclease type III
DTNBP1 dystrobrevin binding protein 1
DVL1 dishevelled segment polarity protein 1
DYNLL2 dynein, light chain, LC8-type 2
EEF2K eukaryotic elongation factor 2 kinase
EGLN1 egl-9 family hypoxia-inducible factor 1
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EIF6 eukaryotic translation initiation factor 6
EPS8 epidermal growth factor receptor pathway substrate 8
FRMPD4 FERM and PDZ domain containing 4
GPSM2 G-protein signaling modulator 2
GRIP2 glutamate receptor interacting protein 2
GRK2 G protein-coupled receptor kinase 2
GRK3 G protein-coupled receptor kinase 3
GSK3B glycogen synthase kinase 3 beta
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HNRNPM heterogeneous nuclear ribonucleoprotein M
HOMER1 homer scaffolding protein 1
HOMER2 homer scaffolding protein 2
HOMER3 homer scaffolding protein 3
HSPA8 heat shock 70kDa protein 8
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KALRN kalirin, RhoGEF kinase
KPNA1 karyopherin alpha 1 (importin alpha 5)
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP1A microtubule-associated protein 1A
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIB1 mindbomb E3 ubiquitin protein ligase 1
MPDZ multiple PDZ domain protein
MYO6 myosin VI
NCKAP1 NCK-associated protein 1
NCOA2 nuclear receptor coactivator 2
NEGR1 neuronal growth regulator 1
NEURL1 neuralized E3 ubiquitin protein ligase 1
NUMB numb homolog (Drosophila)
OPCML opioid binding protein/cell adhesion molecule-like
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PCBP1 poly(rC) binding protein 1
PCBP2 poly(rC) binding protein 2
PCDH7 protocadherin 7
PDLIM4 PDZ and LIM domain 4
PHB1 prohibitin 1
PHB2 prohibitin 2
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PLCB4 phospholipase C, beta 4
PLEKHA5 pleckstrin homology domain containing, family A member 5
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PRICKLE1 prickle homolog 1 (Drosophila)
PRICKLE2 prickle homolog 2 (Drosophila)
PRKCZ protein kinase C, zeta
PURA purine-rich element binding protein A
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RBMX RNA binding motif protein, X-linked
RELN reelin
RGS14 regulator of G-protein signaling 14
RHEBP1 Ras-homolog enriched in brain pseudogene 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPL10A ribosomal protein L10a
RPL12 ribosomal protein L12
RPL14 ribosomal protein L14
RPL17 ribosomal protein L17
RPL18A ribosomal protein L18a
RPL30 ribosomal protein L30
RPL38 ribosomal protein L38
RPL4 ribosomal protein L4
RPL5 ribosomal protein L5
RPL6 ribosomal protein L6
RPL7 ribosomal protein L7
RPL8 ribosomal protein L8
RPLP0 ribosomal protein, large, P0
RPS13 ribosomal protein S13
RPS14 ribosomal protein S14
RPS18 ribosomal protein S18
RPS19 ribosomal protein S19
RPS25 ribosomal protein S25
RPS27 ribosomal protein S27
RPS3 ribosomal protein S3
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
SAMD4A sterile alpha motif domain containing 4A
SH3KBP1 SH3-domain kinase binding protein 1
SHANK1 SH3 and multiple ankyrin repeat domains 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHANK3 SH3 and multiple ankyrin repeat domains 3
SHARPIN SHANK-associated RH domain interactor
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SNAP47 synaptosomal-associated protein, 47kDa
SOS1 son of sevenless homolog 1 (Drosophila)
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STRN striatin, calmodulin binding protein
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
SYT1 synaptotagmin I
TACC3 transforming, acidic coiled-coil containing protein 3
TAMALIN trafficking regulator and scaffold protein tamalin
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
USP8 ubiquitin specific peptidase 8
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
ZDHHC2 zinc finger, DHHC-type containing 2