practolol-5664 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the practolol-5664 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
ADAM22 ADAM metallopeptidase domain 22
ADAM8 ADAM metallopeptidase domain 8
AIM1L absent in melanoma 1-like
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARPP21 cAMP-regulated phosphoprotein, 21kDa
BATF3 basic leucine zipper transcription factor, ATF-like 3
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CACTIN cactin, spliceosome C complex subunit
CARTPT CART prepropeptide
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL2 chemokine (C-C motif) ligand 2
CD1C CD1c molecule
CDA cytidine deaminase
CHAT choline O-acetyltransferase
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNTNAP2 contactin associated protein-like 2
COL14A1 collagen, type XIV, alpha 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CTNS cystinosin, lysosomal cystine transporter
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
DCTN2 dynactin 2 (p50)
DGCR2 DiGeorge syndrome critical region gene 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOCK6 dedicator of cytokinesis 6
EGF epidermal growth factor
ETV1 ets variant 1
ETV6 ets variant 6
EVI2B ecotropic viral integration site 2B
FGF18 fibroblast growth factor 18
FHL1 four and a half LIM domains 1
FOXO4 forkhead box O4
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GADD45G growth arrest and DNA-damage-inducible, gamma
GAMT guanidinoacetate N-methyltransferase
GLRA2 glycine receptor, alpha 2
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
GPR1 G protein-coupled receptor 1
GPR21 G protein-coupled receptor 21
GRIK5 glutamate receptor, ionotropic, kainate 5
GYPC glycophorin C (Gerbich blood group)
HAP1 huntingtin-associated protein 1
HFE hemochromatosis
HOXB9 homeobox B9
HYAL3 hyaluronoglucosaminidase 3
IFNA17 interferon, alpha 17
IGLJ3 immunoglobulin lambda joining 3
IL15 interleukin 15
IL1R1 interleukin 1 receptor, type I
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIF17 kinesin family member 17
KRT2 keratin 2, type II
LAMC2 laminin, gamma 2
LDLRAD4 low density lipoprotein receptor class A domain containing 4
MARS methionyl-tRNA synthetase
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MST1 macrophage stimulating 1
MZF1 myeloid zinc finger 1
NDRG2 NDRG family member 2
NMT1 N-myristoyltransferase 1
NRXN3 neurexin 3
PCSK6 proprotein convertase subtilisin/kexin type 6
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLK3 polo-like kinase 3
PRDM1 PR domain containing 1, with ZNF domain
PRKCA protein kinase C, alpha
PTPRM protein tyrosine phosphatase, receptor type, M
RAB40AL RAB40A, member RAS oncogene family-like
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RECQL5 RecQ protein-like 5
RGS5 regulator of G-protein signaling 5
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RXRB retinoid X receptor, beta
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
STK17A serine/threonine kinase 17a
STS steroid sulfatase (microsomal), isozyme S
TAS2R1 taste receptor, type 2, member 1
TAS2R9 taste receptor, type 2, member 9
TBL1Y transducin (beta)-like 1, Y-linked
TIMP3 TIMP metallopeptidase inhibitor 3
TK2 thymidine kinase 2, mitochondrial
TONSL tonsoku-like, DNA repair protein
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TSSK2 testis-specific serine kinase 2
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VLDLR very low density lipoprotein receptor
WDR78 WD repeat domain 78
ZMAT4 zinc finger, matrin-type 4
ZNF214 zinc finger protein 214
ZNF37BP zinc finger protein 37B, pseudogene

decreased expression

Symbol Name
ACTL8 actin-like 8
ADGRG2 adhesion G protein-coupled receptor G2
AGMAT agmatine ureohydrolase (agmatinase)
ALS2CL ALS2 C-terminal like
AMH anti-Mullerian hormone
AMPD2 adenosine monophosphate deaminase 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAK1 BCL2-antagonist/killer 1
BMP4 bone morphogenetic protein 4
C1ORF105 chromosome 1 open reading frame 105
C4ORF29 chromosome 4 open reading frame 29
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASS4 Cas scaffolding protein family member 4
CCDC25 coiled-coil domain containing 25
CCNO cyclin O
CCP110 centriolar coiled coil protein 110kDa
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CFD complement factor D (adipsin)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CUEDC1 CUE domain containing 1
CXORF21 chromosome X open reading frame 21
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DOCK1 dedicator of cytokinesis 1
DRD1 dopamine receptor D1
EDAR ectodysplasin A receptor
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EVPL envoplakin
FAM155A family with sequence similarity 155, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
GBP2 guanylate binding protein 2, interferon-inducible
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GNL1 guanine nucleotide binding protein-like 1
GSTA4 glutathione S-transferase alpha 4
HDAC11 histone deacetylase 11
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HHLA3 HERV-H LTR-associating 3
HIST1H2AJ histone cluster 1, H2aj
HOXA4 homeobox A4
HPN hepsin
IFT54 intraflagellar transport 54
IGFBP6 insulin-like growth factor binding protein 6
KAT2A K(lysine) acetyltransferase 2A
KIAA0319L KIAA0319-like
KLF2 Kruppel-like factor 2
KLF7 Kruppel-like factor 7 (ubiquitous)
LOC642236 FSHD region gene 1 pseudogene
LONRF3 LON peptidase N-terminal domain and ring finger 3
LOXL1 lysyl oxidase-like 1
LRRC61 leucine rich repeat containing 61
LTC4S leukotriene C4 synthase
NES nestin
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PGR progesterone receptor
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLL polymerase (DNA directed), lambda
PRODH proline dehydrogenase (oxidase) 1
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RAB3D RAB3D, member RAS oncogene family
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF39 ring finger protein 39
S100A2 S100 calcium binding protein A2
SCD5 stearoyl-CoA desaturase 5
SCN1B sodium channel, voltage gated, type I beta subunit
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLMO1 slowmo homolog 1 (Drosophila)
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SOX12 SRY (sex determining region Y)-box 12
SP1 Sp1 transcription factor
SPINK5 serine peptidase inhibitor, Kazal type 5
TAOK1 TAO kinase 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBR1 T-box, brain, 1
TDRD12 tudor domain containing 12
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TM6SF1 transmembrane 6 superfamily member 1
TMEM212 transmembrane protein 212
TREM1 triggering receptor expressed on myeloid cells 1
TRIM25 tripartite motif containing 25
TRIP11 thyroid hormone receptor interactor 11
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
UBTD1 ubiquitin domain containing 1
UNC119 unc-119 homolog (C. elegans)
USP27X ubiquitin specific peptidase 27, X-linked
VASH2 vasohibin 2
VAV1 vav 1 guanine nucleotide exchange factor
ZBTB38 zinc finger and BTB domain containing 38
ZNF408 zinc finger protein 408
ZNF767P zinc finger family member 767, pseudogene
ZNF804A zinc finger protein 804A
ZNF816 zinc finger protein 816
ZNF862 zinc finger protein 862