| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the practolol-5664 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTN2 | actinin, alpha 2 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADAM8 | ADAM metallopeptidase domain 8 |
| AIM1L | absent in melanoma 1-like |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ARPP21 | cAMP-regulated phosphoprotein, 21kDa |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CACTIN | cactin, spliceosome C complex subunit |
| CARTPT | CART prepropeptide |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD1C | CD1c molecule |
| CDA | cytidine deaminase |
| CHAT | choline O-acetyltransferase |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CNTNAP2 | contactin associated protein-like 2 |
| COL14A1 | collagen, type XIV, alpha 1 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 |
| DCTN2 | dynactin 2 (p50) |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOCK6 | dedicator of cytokinesis 6 |
| EGF | epidermal growth factor |
| ETV1 | ets variant 1 |
| ETV6 | ets variant 6 |
| EVI2B | ecotropic viral integration site 2B |
| FGF18 | fibroblast growth factor 18 |
| FHL1 | four and a half LIM domains 1 |
| FOXO4 | forkhead box O4 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GAMT | guanidinoacetate N-methyltransferase |
| GLRA2 | glycine receptor, alpha 2 |
| GNAT1 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 |
| GPR1 | G protein-coupled receptor 1 |
| GPR21 | G protein-coupled receptor 21 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GYPC | glycophorin C (Gerbich blood group) |
| HAP1 | huntingtin-associated protein 1 |
| HFE | hemochromatosis |
| HOXB9 | homeobox B9 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IFNA17 | interferon, alpha 17 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IL15 | interleukin 15 |
| IL1R1 | interleukin 1 receptor, type I |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIF17 | kinesin family member 17 |
| KRT2 | keratin 2, type II |
| LAMC2 | laminin, gamma 2 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| MARS | methionyl-tRNA synthetase |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MST1 | macrophage stimulating 1 |
| MZF1 | myeloid zinc finger 1 |
| NDRG2 | NDRG family member 2 |
| NMT1 | N-myristoyltransferase 1 |
| NRXN3 | neurexin 3 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLK3 | polo-like kinase 3 |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PRKCA | protein kinase C, alpha |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| RAB40AL | RAB40A, member RAS oncogene family-like |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 |
| RECQL5 | RecQ protein-like 5 |
| RGS5 | regulator of G-protein signaling 5 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RXRB | retinoid X receptor, beta |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
| STK17A | serine/threonine kinase 17a |
| STS | steroid sulfatase (microsomal), isozyme S |
| TAS2R1 | taste receptor, type 2, member 1 |
| TAS2R9 | taste receptor, type 2, member 9 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TK2 | thymidine kinase 2, mitochondrial |
| TONSL | tonsoku-like, DNA repair protein |
| TP53AIP1 | tumor protein p53 regulated apoptosis inducing protein 1 |
| TRPM1 | transient receptor potential cation channel, subfamily M, member 1 |
| TSSK2 | testis-specific serine kinase 2 |
| UCP3 | uncoupling protein 3 (mitochondrial, proton carrier) |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| VLDLR | very low density lipoprotein receptor |
| WDR78 | WD repeat domain 78 |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF214 | zinc finger protein 214 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ALS2CL | ALS2 C-terminal like |
| AMH | anti-Mullerian hormone |
| AMPD2 | adenosine monophosphate deaminase 2 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BAK1 | BCL2-antagonist/killer 1 |
| BMP4 | bone morphogenetic protein 4 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CASS4 | Cas scaffolding protein family member 4 |
| CCDC25 | coiled-coil domain containing 25 |
| CCNO | cyclin O |
| CCP110 | centriolar coiled coil protein 110kDa |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CFD | complement factor D (adipsin) |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CUEDC1 | CUE domain containing 1 |
| CXORF21 | chromosome X open reading frame 21 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DOCK1 | dedicator of cytokinesis 1 |
| DRD1 | dopamine receptor D1 |
| EDAR | ectodysplasin A receptor |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EVPL | envoplakin |
| FAM155A | family with sequence similarity 155, member A |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HDAC11 | histone deacetylase 11 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOXA4 | homeobox A4 |
| HPN | hepsin |
| IFT54 | intraflagellar transport 54 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| KAT2A | K(lysine) acetyltransferase 2A |
| KIAA0319L | KIAA0319-like |
| KLF2 | Kruppel-like factor 2 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| LOC642236 | FSHD region gene 1 pseudogene |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LOXL1 | lysyl oxidase-like 1 |
| LRRC61 | leucine rich repeat containing 61 |
| LTC4S | leukotriene C4 synthase |
| NES | nestin |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PGR | progesterone receptor |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POLL | polymerase (DNA directed), lambda |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| RAB3D | RAB3D, member RAS oncogene family |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF39 | ring finger protein 39 |
| S100A2 | S100 calcium binding protein A2 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SP1 | Sp1 transcription factor |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| TAOK1 | TAO kinase 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBR1 | T-box, brain, 1 |
| TDRD12 | tudor domain containing 12 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM212 | transmembrane protein 212 |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TRIM25 | tripartite motif containing 25 |
| TRIP11 | thyroid hormone receptor interactor 11 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| UBTD1 | ubiquitin domain containing 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VASH2 | vasohibin 2 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZNF408 | zinc finger protein 408 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF804A | zinc finger protein 804A |
| ZNF816 | zinc finger protein 816 |
| ZNF862 | zinc finger protein 862 |