| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the pralidoxime-3066 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| C20ORF27 | chromosome 20 open reading frame 27 |
| CALML3 | calmodulin-like 3 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CBR3 | carbonyl reductase 3 |
| CCDC82 | coiled-coil domain containing 82 |
| CD59 | CD59 molecule, complement regulatory protein |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEP41 | centrosomal protein 41kDa |
| CMKLR1 | chemerin chemokine-like receptor 1 |
| COPS7B | COP9 signalosome subunit 7B |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CTAGE1 | cutaneous T-cell lymphoma-associated antigen 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| EFNB3 | ephrin-B3 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| EMC3 | ER membrane protein complex subunit 3 |
| ETV1 | ets variant 1 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 |
| FAM76A | family with sequence similarity 76, member A |
| FGFR1 | fibroblast growth factor receptor 1 |
| FHL3 | four and a half LIM domains 3 |
| FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GSPT1 | G1 to S phase transition 1 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 |
| HDLBP | high density lipoprotein binding protein |
| HOXA10 | homeobox A10 |
| HOXA11 | homeobox A11 |
| HOXC10 | homeobox C10 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| IL1RN | interleukin 1 receptor antagonist |
| IL3RA | interleukin 3 receptor, alpha (low affinity) |
| INSL4 | insulin-like 4 (placenta) |
| JAG2 | jagged 2 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIF5C | kinesin family member 5C |
| KLF15 | Kruppel-like factor 15 |
| LAD1 | ladinin 1 |
| LATS1 | large tumor suppressor kinase 1 |
| LDLR | low density lipoprotein receptor |
| LHB | luteinizing hormone beta polypeptide |
| LOC100287590 | uncharacterized LOC100287590 |
| LRRC37BP1 | leucine rich repeat containing 37B pseudogene 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP4 | microtubule-associated protein 4 |
| MID2 | midline 2 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MPZL1 | myelin protein zero-like 1 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MTAP | methylthioadenosine phosphorylase |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NCLN | nicalin |
| NOX1 | NADPH oxidase 1 |
| NUP188 | nucleoporin 188kDa |
| NUP54 | nucleoporin 54kDa |
| OR52A1 | olfactory receptor, family 52, subfamily A, member 1 |
| PALLD | palladin, cytoskeletal associated protein |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| PRKCE | protein kinase C, epsilon |
| PSG7 | pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RAB13 | RAB13, member RAS oncogene family |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) |
| RASAL2 | RAS protein activator like 2 |
| RHAG | Rh-associated glycoprotein |
| RPL10 | ribosomal protein L10 |
| RPL7 | ribosomal protein L7 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIX3 | SIX homeobox 3 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC39A2 | solute carrier family 39 (zinc transporter), member 2 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SMAD5 | SMAD family member 5 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SOCS7 | suppressor of cytokine signaling 7 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TDRD1 | tudor domain containing 1 |
| TRGV5 | T cell receptor gamma variable 5 |
| VASH2 | vasohibin 2 |
| VCX2 | variable charge, X-linked 2 |
| ZFHX4 | zinc finger homeobox 4 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF235 | zinc finger protein 235 |
| ZNF444 | zinc finger protein 444 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| AEN | apoptosis enhancing nuclease |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ART1 | ADP-ribosyltransferase 1 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CENPB | centromere protein B, 80kDa |
| CFAP69 | cilia and flagella associated protein 69 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLDN15 | claudin 15 |
| CLEC16A | C-type lectin domain family 16, member A |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CORO7 | coronin 7 |
| CORT | cortistatin |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTSD | cathepsin D |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DYM | dymeclin |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EPHA4 | EPH receptor A4 |
| FAM188A | family with sequence similarity 188, member A |
| FAM53B | family with sequence similarity 53, member B |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOXO4 | forkhead box O4 |
| G6PD | glucose-6-phosphate dehydrogenase |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H4A | histone cluster 1, H4a |
| HPSE | heparanase |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IGLV1-44 | immunoglobulin lambda variable 1-44 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| ITGA10 | integrin, alpha 10 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LTC4S | leukotriene C4 synthase |
| MAP3K7CL | MAP3K7 C-terminal like |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MED31 | mediator complex subunit 31 |
| MPI | mannose phosphate isomerase |
| NAG18 | NAG18 mRNA |
| NCS1 | neuronal calcium sensor 1 |
| NINJ2 | ninjurin 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POM121 | POM121 transmembrane nucleoporin |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SETD1A | SET domain containing 1A |
| SHPK | sedoheptulokinase |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| STAT5A | signal transducer and activator of transcription 5A |
| STEAP3 | STEAP family member 3, metalloreductase |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| THAP10 | THAP domain containing 10 |
| THEM6 | thioesterase superfamily member 6 |
| TMC5 | transmembrane channel-like 5 |
| TMEM180 | transmembrane protein 180 |
| TMEM206 | transmembrane protein 206 |
| TMEM212 | transmembrane protein 212 |
| TMEM246 | transmembrane protein 246 |
| TPM3 | tropomyosin 3 |
| TRAIP | TRAF interacting protein |
| TRMT61A | tRNA methyltransferase 61A |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TUBG2 | tubulin, gamma 2 |
| UBQLN4 | ubiquilin 4 |
| UBXN6 | UBX domain protein 6 |
| UCN | urocortin |
| WDR33 | WD repeat domain 33 |
| ZNF254 | zinc finger protein 254 |
| ZNF280B | zinc finger protein 280B |
| ZNF768 | zinc finger protein 768 |
