| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the pralidoxime-5383 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ACRV1 | acrosomal vesicle protein 1 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADCK2 | aarF domain containing kinase 2 |
| AFAP1 | actin filament associated protein 1 |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| APP | amyloid beta (A4) precursor protein |
| BMP5 | bone morphogenetic protein 5 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C3 | complement component 3 |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CDK13 | cyclin-dependent kinase 13 |
| CDK16 | cyclin-dependent kinase 16 |
| CFP | complement factor properdin |
| CHN2 | chimerin 2 |
| CLGN | calmegin |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| COL11A2 | collagen, type XI, alpha 2 |
| COL5A2 | collagen, type V, alpha 2 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CORO7 | coronin 7 |
| CPQ | carboxypeptidase Q |
| CSTA | cystatin A (stefin A) |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DAGLA | diacylglycerol lipase, alpha |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DIO2 | deiodinase, iodothyronine, type II |
| DMPK | dystrophia myotonica-protein kinase |
| DOCK5 | dedicator of cytokinesis 5 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| F9 | coagulation factor IX |
| FER | fer (fps/fes related) tyrosine kinase |
| FGF23 | fibroblast growth factor 23 |
| FGFR4 | fibroblast growth factor receptor 4 |
| FN1 | fibronectin 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GNAS | GNAS complex locus |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GSPT1 | G1 to S phase transition 1 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIST1H2BN | histone cluster 1, H2bn |
| HNF1A | HNF1 homeobox A |
| ICOSLG | inducible T-cell co-stimulator ligand |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| JAK2 | Janus kinase 2 |
| KIF1C | kinesin family member 1C |
| KLF6 | Kruppel-like factor 6 |
| LEFTY1 | left-right determination factor 1 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LMAN1 | lectin, mannose-binding, 1 |
| LOC647070 | uncharacterized LOC647070 |
| MCC | mutated in colorectal cancers |
| MDFI | MyoD family inhibitor |
| MEF2D | myocyte enhancer factor 2D |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase |
| MLNR | motilin receptor |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NUP188 | nucleoporin 188kDa |
| OPRL1 | opiate receptor-like 1 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PHOX2A | paired-like homeobox 2a |
| PIDD1 | p53-induced death domain protein 1 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLAU | plasminogen activator, urokinase |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLK4 | polo-like kinase 4 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRDM14 | PR domain containing 14 |
| PTN | pleiotrophin |
| RAB6A | RAB6A, member RAS oncogene family |
| RETN | resistin |
| RGS2 | regulator of G-protein signaling 2 |
| RGS4 | regulator of G-protein signaling 4 |
| RHEB | Ras homolog enriched in brain |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SCLY | selenocysteine lyase |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa |
| SIK3 | SIK family kinase 3 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor |
| SSTR4 | somatostatin receptor 4 |
| TLE2 | transducin-like enhancer of split 2 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ALPK1 | alpha-kinase 1 |
| APOD | apolipoprotein D |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| BST2 | bone marrow stromal cell antigen 2 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CAPN15 | calpain 15 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC25 | coiled-coil domain containing 25 |
| CCDC9 | coiled-coil domain containing 9 |
| CCNO | cyclin O |
| CHM | choroideremia (Rab escort protein 1) |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLSPN | claspin |
| CPTP | ceramide-1-phosphate transfer protein |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| EFNA3 | ephrin-A3 |
| ELMO3 | engulfment and cell motility 3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETNK2 | ethanolamine kinase 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM212B | family with sequence similarity 212, member B |
| FAM46C | family with sequence similarity 46, member C |
| FLJ22184 | |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H2AL | histone cluster 1, H2al |
| HIST1H3B | histone cluster 1, H3b |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KIAA0355 | KIAA0355 |
| LAMB3 | laminin, beta 3 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| MDM4 | MDM4, p53 regulator |
| METTL16 | methyltransferase like 16 |
| MITF | microphthalmia-associated transcription factor |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MYO1E | myosin IE |
| NME5 | NME/NM23 family member 5 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| P3H1 | prolyl 3-hydroxylase 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RAB3A | RAB3A, member RAS oncogene family |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SALL2 | spalt-like transcription factor 2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCHIP1 | schwannomin interacting protein 1 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SNIP1 | Smad nuclear interacting protein 1 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| ST5 | suppression of tumorigenicity 5 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TET3 | tet methylcytosine dioxygenase 3 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| THBS3 | thrombospondin 3 |
| TLN1 | talin 1 |
| TMEM121 | transmembrane protein 121 |
| TMEM212 | transmembrane protein 212 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VEGFB | vascular endothelial growth factor B |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| ZNF16 | zinc finger protein 16 |
| ZNF35 | zinc finger protein 35 |
| ZNF510 | zinc finger protein 510 |
| ZNF573 | zinc finger protein 573 |
