| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the pralidoxime-6283 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX3 | acyl-CoA oxidase 3, pristanoyl |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AIM1L | absent in melanoma 1-like |
| ALDOB | aldolase B, fructose-bisphosphate |
| APOM | apolipoprotein M |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| BCR | breakpoint cluster region |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC87 | coiled-coil domain containing 87 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CDK20 | cyclin-dependent kinase 20 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNTFR | ciliary neurotrophic factor receptor |
| COL6A1 | collagen, type VI, alpha 1 |
| COL7A1 | collagen, type VII, alpha 1 |
| CPNE7 | copine VII |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| DBP | D site of albumin promoter (albumin D-box) binding protein |
| DZIP1 | DAZ interacting zinc finger protein 1 |
| EFNA3 | ephrin-A3 |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| ESR1 | estrogen receptor 1 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 |
| FAM214B | family with sequence similarity 214, member B |
| FAS | Fas cell surface death receptor |
| FKBP8 | FK506 binding protein 8, 38kDa |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GPC3 | glypican 3 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GRK5 | G protein-coupled receptor kinase 5 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HOXB5 | homeobox B5 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IL6ST | interleukin 6 signal transducer |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KIF5A | kinesin family member 5A |
| KLHL29 | kelch-like family member 29 |
| KLHL36 | kelch-like family member 36 |
| KRT17 | keratin 17, type I |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOXL2 | lysyl oxidase-like 2 |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| MAL | mal, T-cell differentiation protein |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| METTL7A | methyltransferase like 7A |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYOZ3 | myozenin 3 |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PLXNC1 | plexin C1 |
| PPEF1 | protein phosphatase, EF-hand calcium binding domain 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| RAB11B | RAB11B, member RAS oncogene family |
| RAD51 | RAD51 recombinase |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RRAGB | Ras-related GTP binding B |
| RREB1 | ras responsive element binding protein 1 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SIX3 | SIX homeobox 3 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPATA6 | spermatogenesis associated 6 |
| SVIL | supervillin |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TAT | tyrosine aminotransferase |
| TBCD | tubulin folding cofactor D |
| TK2 | thymidine kinase 2, mitochondrial |
| TLR2 | toll-like receptor 2 |
| USP22 | ubiquitin specific peptidase 22 |
| VASH1 | vasohibin 1 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| WWOX | WW domain containing oxidoreductase |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| ZC3H11A | zinc finger CCCH-type containing 11A |
| ZMYND11 | zinc finger, MYND-type containing 11 |
| ZNF292 | zinc finger protein 292 |
| Symbol | Name |
|---|---|
| ADCY7 | adenylate cyclase 7 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARRB2 | arrestin, beta 2 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| CCDC69 | coiled-coil domain containing 69 |
| CCDC88C | coiled-coil domain containing 88C |
| CCDC9 | coiled-coil domain containing 9 |
| CD70 | CD70 molecule |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) |
| CEP85 | centrosomal protein 85kDa |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CNN2 | calponin 2 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DEAF1 | DEAF1 transcription factor |
| EGF | epidermal growth factor |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| EN2 | engrailed homeobox 2 |
| ERCC2 | excision repair cross-complementation group 2 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FER | fer (fps/fes related) tyrosine kinase |
| FKBPL | FK506 binding protein like |
| FUZ | fuzzy planar cell polarity protein |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GRAMD4 | GRAM domain containing 4 |
| GRPR | gastrin-releasing peptide receptor |
| HIST1H3B | histone cluster 1, H3b |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HYI | hydroxypyruvate isomerase (putative) |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| KRT6A | keratin 6A, type II |
| LOC100127972 | uncharacterized LOC100127972 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MGC12488 | |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MOXD1 | monooxygenase, DBH-like 1 |
| NADSYN1 | NAD synthetase 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| ONECUT2 | one cut homeobox 2 |
| PALMD | palmdelphin |
| PDE12 | phosphodiesterase 12 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB4B | RAB4B, member RAS oncogene family |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF141 | ring finger protein 141 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SDC3 | syndecan 3 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SPATA2L | spermatogenesis associated 2-like |
| STBD1 | starch binding domain 1 |
| SYNC | syncoilin, intermediate filament protein |
| TMEM132A | transmembrane protein 132A |
| TMEM2 | transmembrane protein 2 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TUBA3D | tubulin, alpha 3d |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| USB1 | U6 snRNA biogenesis 1 |
| USP32 | ubiquitin specific peptidase 32 |
| VEGFB | vascular endothelial growth factor B |
| XAB2 | XPA binding protein 2 |
| ZNF197 | zinc finger protein 197 |
| ZNF205 | zinc finger protein 205 |
| ZNF385D | zinc finger protein 385D |
| ZNF710 | zinc finger protein 710 |
| ZNF862 | zinc finger protein 862 |
