| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
198 genes differentially expressed following the pralidoxime-6443 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ACVR1B | activin A receptor, type IB |
| AJAP1 | adherens junctions associated protein 1 |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ANGPT4 | angiopoietin 4 |
| ANKMY1 | ankyrin repeat and MYND domain containing 1 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| AQP1 | aquaporin 1 (Colton blood group) |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CD4 | CD4 molecule |
| CD47 | CD47 molecule |
| CLEC1A | C-type lectin domain family 1, member A |
| CLGN | calmegin |
| CLPS | colipase, pancreatic |
| CNTD2 | cyclin N-terminal domain containing 2 |
| COMT | catechol-O-methyltransferase |
| DENND5B | DENN/MADD domain containing 5B |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DUSP10 | dual specificity phosphatase 10 |
| EBF2 | early B-cell factor 2 |
| EFNB3 | ephrin-B3 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| ESM1 | endothelial cell-specific molecule 1 |
| FAM46C | family with sequence similarity 46, member C |
| FER | fer (fps/fes related) tyrosine kinase |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GOLGA2P5 | golgin A2 pseudogene 5 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HFE | hemochromatosis |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IBSP | integrin-binding sialoprotein |
| IDUA | iduronidase, alpha-L- |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| INHBA | inhibin, beta A |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KRT17 | keratin 17, type I |
| LECT2 | leukocyte cell-derived chemotaxin 2 |
| LRRN3 | leucine rich repeat neuronal 3 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MEFV | Mediterranean fever |
| MMRN2 | multimerin 2 |
| MOB3B | MOB kinase activator 3B |
| MYLK | myosin light chain kinase |
| NEK9 | NIMA-related kinase 9 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PCDH11Y | protocadherin 11 Y-linked |
| PCDHB3 | protocadherin beta 3 |
| PDE11A | phosphodiesterase 11A |
| PEG10 | paternally expressed 10 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| POPDC2 | popeye domain containing 2 |
| POU6F2 | POU class 6 homeobox 2 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 |
| PTH1R | parathyroid hormone 1 receptor |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| QSER1 | glutamine and serine rich 1 |
| RAP1GAP | RAP1 GTPase activating protein |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM12B | RNA binding motif protein 12B |
| RGS11 | regulator of G-protein signaling 11 |
| RGS12 | regulator of G-protein signaling 12 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SAA4 | serum amyloid A4, constitutive |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit |
| SFTPD | surfactant protein D |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SPTA1 | spectrin, alpha, erythrocytic 1 |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
| TBX2 | T-box 2 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TTN | titin |
| TUBA4B | tubulin, alpha 4b |
| UBOX5 | U-box domain containing 5 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| YY2 | YY2 transcription factor |
| ZIM2 | zinc finger, imprinted 2 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACTL8 | actin-like 8 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARMC6 | armadillo repeat containing 6 |
| ASPN | asporin |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BMP15 | bone morphogenetic protein 15 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CCDC186 | coiled-coil domain containing 186 |
| CEP85 | centrosomal protein 85kDa |
| CFAP44 | cilia and flagella associated protein 44 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOCK4 | dedicator of cytokinesis 4 |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EXOC5 | exocyst complex component 5 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIRA | histone cell cycle regulator |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H4D | histone cluster 1, H4d |
| HMOX1 | heme oxygenase 1 |
| HOXC5 | homeobox C5 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IRF1 | interferon regulatory factor 1 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIFC1 | kinesin family member C1 |
| KRT13 | keratin 13, type I |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| LRRC61 | leucine rich repeat containing 61 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MGC12488 | |
| MOSPD3 | motile sperm domain containing 3 |
| MPI | mannose phosphate isomerase |
| MXD3 | MAX dimerization protein 3 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| OLFML2A | olfactomedin-like 2A |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PADI1 | peptidyl arginine deiminase, type I |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PER3 | period circadian clock 3 |
| PGP | phosphoglycolate phosphatase |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PRKX | protein kinase, X-linked |
| PROL1 | proline rich, lacrimal 1 |
| PRR7 | proline rich 7 (synaptic) |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| PYGB | phosphorylase, glycogen; brain |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RPAP2 | RNA polymerase II associated protein 2 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SSPN | sarcospan |
| STK16 | serine/threonine kinase 16 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYNC | syncoilin, intermediate filament protein |
| TAOK1 | TAO kinase 1 |
| TCTN1 | tectonic family member 1 |
| THBS3 | thrombospondin 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM183A | transmembrane protein 183A |
| TMEM2 | transmembrane protein 2 |
| TNS2 | tensin 2 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TSPAN1 | tetraspanin 1 |
| TWF2 | twinfilin actin binding protein 2 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| USP20 | ubiquitin specific peptidase 20 |
| VEGFB | vascular endothelial growth factor B |
| WDR18 | WD repeat domain 18 |
| ZNF248 | zinc finger protein 248 |
| ZNF430 | zinc finger protein 430 |
| ZNF574 | zinc finger protein 574 |
| ZNF768 | zinc finger protein 768 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
