| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the pramocaine-3811 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADGRB3 | adhesion G protein-coupled receptor B3 |
| AFF1 | AF4/FMR2 family, member 1 |
| ALOX5 | arachidonate 5-lipoxygenase |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
| APAF1 | apoptotic peptidase activating factor 1 |
| ARTN | artemin |
| ATF6B | activating transcription factor 6 beta |
| ATN1 | atrophin 1 |
| C10ORF12 | chromosome 10 open reading frame 12 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCR8 | chemokine (C-C motif) receptor 8 |
| CD53 | CD53 molecule |
| CLCA2 | chloride channel accessory 2 |
| CLTA | clathrin, light chain A |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| COL6A1 | collagen, type VI, alpha 1 |
| CREBBP | CREB binding protein |
| CROCCP3 | ciliary rootlet coiled-coil, rootletin pseudogene 3 |
| CTSS | cathepsin S |
| CYP3A7 | cytochrome P450, family 3, subfamily A, polypeptide 7 |
| DEPDC5 | DEP domain containing 5 |
| DOCK6 | dedicator of cytokinesis 6 |
| DOCK9 | dedicator of cytokinesis 9 |
| DSCAM | Down syndrome cell adhesion molecule |
| DSCC1 | DNA replication and sister chromatid cohesion 1 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| ETV1 | ets variant 1 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FRZB | frizzled-related protein |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HAB1 | B1 for mucin |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IL1RN | interleukin 1 receptor antagonist |
| IL5RA | interleukin 5 receptor, alpha |
| IL6R | interleukin 6 receptor |
| INCENP | inner centromere protein antigens 135/155kDa |
| JUND | jun D proto-oncogene |
| KITLG | KIT ligand |
| KLK3 | kallikrein-related peptidase 3 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMO1 | LIM domain only 1 (rhombotin 1) |
| LOC257152 | uncharacterized LOC257152 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| METTL16 | methyltransferase like 16 |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MXRA5 | matrix-remodelling associated 5 |
| MYO1F | myosin IF |
| N4BP1 | NEDD4 binding protein 1 |
| NCOR2 | nuclear receptor corepressor 2 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NF1 | neurofibromin 1 |
| NOX4 | NADPH oxidase 4 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PRDM14 | PR domain containing 14 |
| PRKCI | protein kinase C, iota |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| RAB6A | RAB6A, member RAS oncogene family |
| RB1 | retinoblastoma 1 |
| RETN | resistin |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SERPINA10 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 |
| SFTPB | surfactant protein B |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
| SNTG1 | syntrophin, gamma 1 |
| SOX10 | SRY (sex determining region Y)-box 10 |
| SP110 | SP110 nuclear body protein |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| TMPRSS11D | transmembrane protease, serine 11D |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TP73-AS1 | TP73 antisense RNA 1 |
| TTC9 | tetratricopeptide repeat domain 9 |
| TUBB7P | tubulin, beta 7, pseudogene |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VAMP5 | vesicle-associated membrane protein 5 |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) |
| WDR59 | WD repeat domain 59 |
| WNT3 | wingless-type MMTV integration site family, member 3 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ACSS3 | acyl-CoA synthetase short-chain family member 3 |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| ALPK1 | alpha-kinase 1 |
| ANXA10 | annexin A10 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ATG10 | autophagy related 10 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| AURKC | aurora kinase C |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BBC3 | BCL2 binding component 3 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C9ORF114 | chromosome 9 open reading frame 114 |
| CCDC106 | coiled-coil domain containing 106 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLSTN3 | calsyntenin 3 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| CYTH3 | cytohesin 3 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| EGFL7 | EGF-like-domain, multiple 7 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EPPK1 | epiplakin 1 |
| ERCC4 | excision repair cross-complementation group 4 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| FZD8 | frizzled class receptor 8 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLB1L | galactosidase, beta 1-like |
| GMPR | guanosine monophosphate reductase |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HCFC1 | host cell factor C1 |
| HHAT | hedgehog acyltransferase |
| HIST1H2AK | histone cluster 1, H2ak |
| HOXB2 | homeobox B2 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IFNA17 | interferon, alpha 17 |
| IL24 | interleukin 24 |
| INO80D | INO80 complex subunit D |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| JUNB | jun B proto-oncogene |
| KIAA0754 | KIAA0754 |
| KIAA0894 | KIAA0894 protein |
| KRT4 | keratin 4, type II |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LRRC15 | leucine rich repeat containing 15 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAP2 | microtubule-associated protein 2 |
| MBTD1 | mbt domain containing 1 |
| MEGF8 | multiple EGF-like-domains 8 |
| NABP1 | nucleic acid binding protein 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NDP | Norrie disease (pseudoglioma) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NLGN1 | neuroligin 1 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| NTNG1 | netrin G1 |
| OSR2 | odd-skipped related transciption factor 2 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PIP | prolactin-induced protein |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRPH | peripherin |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PRSS22 | protease, serine, 22 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RGL2 | ral guanine nucleotide dissociation stimulator-like 2 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SETD1A | SET domain containing 1A |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| STXBP5L | syntaxin binding protein 5-like |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMEM19 | transmembrane protein 19 |
| TMEM74B | transmembrane protein 74B |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TRAIP | TRAF interacting protein |
| TRIM16 | tripartite motif containing 16 |
| VGF | VGF nerve growth factor inducible |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZNF264 | zinc finger protein 264 |
| ZNF426 | zinc finger protein 426 |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
| ZNF747 | zinc finger protein 747 |
