| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the pramocaine-6054 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALOX5 | arachidonate 5-lipoxygenase |
| ALOXE3 | arachidonate lipoxygenase 3 |
| ANKRD55 | ankyrin repeat domain 55 |
| APOE | apolipoprotein E |
| AREG | amphiregulin |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| C14ORF105 | chromosome 14 open reading frame 105 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CD200 | CD200 molecule |
| CD70 | CD70 molecule |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| COL11A1 | collagen, type XI, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COL9A3 | collagen, type IX, alpha 3 |
| CTIF | CBP80/20-dependent translation initiation factor |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DPP4 | dipeptidyl-peptidase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| ECE1 | endothelin converting enzyme 1 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| ETV7 | ets variant 7 |
| FAM120C | family with sequence similarity 120C |
| FGF6 | fibroblast growth factor 6 |
| FHL1 | four and a half LIM domains 1 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GK2 | glycerol kinase 2 |
| GPR137 | G protein-coupled receptor 137 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GSAP | gamma-secretase activating protein |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HR | hair growth associated |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KCNJ4 | potassium channel, inwardly rectifying subfamily J, member 4 |
| KLHL25 | kelch-like family member 25 |
| LENEP | lens epithelial protein |
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LIPE | lipase, hormone-sensitive |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LRRC75B | leucine rich repeat containing 75B |
| LYZL6 | lysozyme-like 6 |
| MLXIPL | MLX interacting protein-like |
| MNMIP1 | manchette microtubule inner protein 1 |
| MYO7A | myosin VIIA |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NAG18 | NAG18 mRNA |
| NCAN | neurocan |
| NPPA | natriuretic peptide A |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| OR7E24 | olfactory receptor, family 7, subfamily E, member 24 |
| PARP11 | poly (ADP-ribose) polymerase family, member 11 |
| PCDHB13 | protocadherin beta 13 |
| POLM | polymerase (DNA directed), mu |
| PRF1 | perforin 1 (pore forming protein) |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RFPL3 | ret finger protein-like 3 |
| RGS12 | regulator of G-protein signaling 12 |
| RGS14 | regulator of G-protein signaling 14 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RTN2 | reticulon 2 |
| RXRB | retinoid X receptor, beta |
| SAA3P | serum amyloid A3 pseudogene |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SH3BP2 | SH3-domain binding protein 2 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SHOX2 | short stature homeobox 2 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLA | Src-like-adaptor |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SNTA1 | syntrophin, alpha 1 |
| SNX1 | sorting nexin 1 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| STAC | SH3 and cysteine rich domain |
| STC1 | stanniocalcin 1 |
| STEAP4 | STEAP family member 4 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TAPBP | TAP binding protein (tapasin) |
| TBC1D22B | TBC1 domain family, member 22B |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| THRB | thyroid hormone receptor, beta |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TRD | T cell receptor delta locus |
| TTC38 | tetratricopeptide repeat domain 38 |
| VNN2 | vanin 2 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF259P1 | zinc finger protein 259 pseudogene 1 |
| Symbol | Name |
|---|---|
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARSB | arylsulfatase B |
| ATG10 | autophagy related 10 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLDN17 | claudin 17 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNTFR | ciliary neurotrophic factor receptor |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CPB1 | carboxypeptidase B1 (tissue) |
| CRMP1 | collapsin response mediator protein 1 |
| CXORF56 | chromosome X open reading frame 56 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERCC6 | excision repair cross-complementation group 6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM110B | family with sequence similarity 110, member B |
| FMOD | fibromodulin |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GPC3 | glypican 3 |
| GRPR | gastrin-releasing peptide receptor |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H4C | histone cluster 1, H4c |
| HOXC11 | homeobox C11 |
| IFT81 | intraflagellar transport 81 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLHL28 | kelch-like family member 28 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMX1B | LIM homeobox transcription factor 1, beta |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MGC12488 | |
| MSI1 | musashi RNA-binding protein 1 |
| NEUROD4 | neuronal differentiation 4 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| ONECUT2 | one cut homeobox 2 |
| P2RY4 | pyrimidinergic receptor P2Y, G-protein coupled, 4 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDHA6 | protocadherin alpha 6 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLD2 | phospholipase D2 |
| PODXL2 | podocalyxin-like 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB30 | RAB30, member RAS oncogene family |
| RFXAP | regulatory factor X-associated protein |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF208 | ring finger protein 208 |
| RPGR | retinitis pigmentosa GTPase regulator |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMAD5 | SMAD family member 5 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| STRA6 | stimulated by retinoic acid 6 |
| SYNC | syncoilin, intermediate filament protein |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM242 | transmembrane protein 242 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNS2 | tensin 2 |
| TOR4A | torsin family 4, member A |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBQLN4 | ubiquilin 4 |
| USP18 | ubiquitin specific peptidase 18 |
| WDR33 | WD repeat domain 33 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF280D | zinc finger protein 280D |
| ZNF324 | zinc finger protein 324 |
| ZNF362 | zinc finger protein 362 |
| ZNF428 | zinc finger protein 428 |
