prasterone-3097 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the prasterone-3097 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALOX5 arachidonate 5-lipoxygenase
ASPH aspartate beta-hydroxylase
ATF5 activating transcription factor 5
ATG10 autophagy related 10
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C11ORF16 chromosome 11 open reading frame 16
C19ORF73 chromosome 19 open reading frame 73
C3ORF18 chromosome 3 open reading frame 18
C8A complement component 8, alpha polypeptide
CALCB calcitonin-related polypeptide beta
CAMKMT calmodulin-lysine N-methyltransferase
CCDC106 coiled-coil domain containing 106
CCL16 chemokine (C-C motif) ligand 16
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEND1 cell cycle exit and neuronal differentiation 1
COBLL1 cordon-bleu WH2 repeat protein-like 1
CREM cAMP responsive element modulator
CTAG2 cancer/testis antigen 2
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
EGR4 early growth response 4
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
ERICH1 glutamate-rich 1
EXOC7 exocyst complex component 7
FBXO31 F-box protein 31
FRZB frizzled-related protein
GMPR guanosine monophosphate reductase
HAB1 B1 for mucin
HDGFRP3 hepatoma-derived growth factor, related protein 3
HEXIM1 hexamethylene bis-acetamide inducible 1
HSPA2 heat shock 70kDa protein 2
HYAL1 hyaluronoglucosaminidase 1
IBSP integrin-binding sialoprotein
ICOSLG inducible T-cell co-stimulator ligand
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IL1R2 interleukin 1 receptor, type II
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA0513 KIAA0513
KRT81 keratin 81, type II
KSR1 kinase suppressor of ras 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LYRM9 LYR motif containing 9
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MX1 MX dynamin-like GTPase 1
NARFL nuclear prelamin A recognition factor-like
NLE1 notchless homolog 1 (Drosophila)
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRG1 neuregulin 1
NUDCD3 NudC domain containing 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAX5 paired box 5
PBX2 pre-B-cell leukemia homeobox 2
PDE4DIP phosphodiesterase 4D interacting protein
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
POM121L2 POM121 transmembrane nucleoporin-like 2
PTPRJ protein tyrosine phosphatase, receptor type, J
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB15 RAB15, member RAS oncogene family
RAB26 RAB26, member RAS oncogene family
RBM34 RNA binding motif protein 34
REC8 REC8 meiotic recombination protein
RGS10 regulator of G-protein signaling 10
RIF1 replication timing regulatory factor 1
RIMS2 regulating synaptic membrane exocytosis 2
RNF31 ring finger protein 31
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL35A ribosomal protein L35a
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SIX3 SIX homeobox 3
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SORBS3 sorbin and SH3 domain containing 3
SPHK2 sphingosine kinase 2
STAB1 stabilin 1
STARD13 StAR-related lipid transfer (START) domain containing 13
STOML1 stomatin (EPB72)-like 1
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TAAR2 trace amine associated receptor 2
TAT tyrosine aminotransferase
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBX6 T-box 6
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
THBS1 thrombospondin 1
THSD7A thrombospondin, type I, domain containing 7A
TNK1 tyrosine kinase, non-receptor, 1
TNS1 tensin 1
TRPA1 transient receptor potential cation channel, subfamily A, member 1
UBE2I ubiquitin-conjugating enzyme E2I
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
USP29 ubiquitin specific peptidase 29
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADAM15 ADAM metallopeptidase domain 15
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ALPK1 alpha-kinase 1
ANXA2P3 annexin A2 pseudogene 3
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARMC7 armadillo repeat containing 7
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BEND5 BEN domain containing 5
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CEP170B centrosomal protein 170B
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CRELD1 cysteine-rich with EGF-like domains 1
CRYL1 crystallin, lambda 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DUSP8 dual specificity phosphatase 8
ELSPBP1 epididymal sperm binding protein 1
ENO2 enolase 2 (gamma, neuronal)
FCHO1 FCH domain only 1
FGF9 fibroblast growth factor 9
FGGY FGGY carbohydrate kinase domain containing
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FRMD1 FERM domain containing 1
FRS2 fibroblast growth factor receptor substrate 2
FYCO1 FYVE and coiled-coil domain containing 1
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GAMT guanidinoacetate N-methyltransferase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR132 G protein-coupled receptor 132
GTPBP6 GTP binding protein 6 (putative)
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H3G histone cluster 1, H3g
HSPA4L heat shock 70kDa protein 4-like
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
ITPKC inositol-trisphosphate 3-kinase C
KLF3 Kruppel-like factor 3 (basic)
LIN7A lin-7 homolog A (C. elegans)
MAGOHB mago-nashi homolog B (Drosophila)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K2 mitogen-activated protein kinase kinase kinase 2
METTL8 methyltransferase like 8
MREG melanoregulin
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTMR12 myotubularin related protein 12
MYO1E myosin IE
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NABP2 nucleic acid binding protein 2
NR1D2 nuclear receptor subfamily 1, group D, member 2
NSUN3 NOP2/Sun domain family, member 3
NT5C 5', 3'-nucleotidase, cytosolic
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POMZP3 POM121 and ZP3 fusion
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRAF2 PRA1 domain family, member 2
PSKH1 protein serine kinase H1
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PYGB phosphorylase, glycogen; brain
RAB8B RAB8B, member RAS oncogene family
RCAN3 RCAN family member 3
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SKI SKI proto-oncogene
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC2A4RG SLC2A4 regulator
SNX15 sorting nexin 15
SP140 SP140 nuclear body protein
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STEAP3 STEAP family member 3, metalloreductase
TBXAS1 thromboxane A synthase 1 (platelet)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THBS4 thrombospondin 4
TICAM1 toll-like receptor adaptor molecule 1
TMEM180 transmembrane protein 180
TMEM206 transmembrane protein 206
TMEM246 transmembrane protein 246
TNRC6B trinucleotide repeat containing 6B
TRIM36 tripartite motif containing 36
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPS1 trichorhinophalangeal syndrome I
TUBG2 tubulin, gamma 2
UNC13B unc-13 homolog B (C. elegans)
YOD1 YOD1 deubiquitinase
ZBTB10 zinc finger and BTB domain containing 10
ZFHX2 zinc finger homeobox 2
ZFHX3 zinc finger homeobox 3
ZHX2 zinc fingers and homeoboxes 2
ZNF155 zinc finger protein 155
ZNF250 zinc finger protein 250
ZNF280B zinc finger protein 280B
ZNF480 zinc finger protein 480
ZNF747 zinc finger protein 747
ZNHIT2 zinc finger, HIT-type containing 2