| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the prasterone-5019 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ACVR1B | activin A receptor, type IB |
| AFF1 | AF4/FMR2 family, member 1 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AIM2 | absent in melanoma 2 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARTN | artemin |
| ATF3 | activating transcription factor 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 |
| CLTA | clathrin, light chain A |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CTSE | cathepsin E |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DICER1 | dicer 1, ribonuclease type III |
| DUSP1 | dual specificity phosphatase 1 |
| ECE1 | endothelin converting enzyme 1 |
| EGR3 | early growth response 3 |
| EHD2 | EH-domain containing 2 |
| FBXO40 | F-box protein 40 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FLOT1 | flotillin 1 |
| FOXG1 | forkhead box G1 |
| FSCN1 | fascin actin-bundling protein 1 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IL27RA | interleukin 27 receptor, alpha |
| IL6ST | interleukin 6 signal transducer |
| INHBE | inhibin, beta E |
| IRF1 | interferon regulatory factor 1 |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KIAA0125 | KIAA0125 |
| KIAA1456 | KIAA1456 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MFAP2 | microfibrillar-associated protein 2 |
| MIIP | migration and invasion inhibitory protein |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PAX2 | paired box 2 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLAT | plasminogen activator, tissue |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PVR | poliovirus receptor |
| RARA | retinoic acid receptor, alpha |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SETBP1 | SET binding protein 1 |
| SLC45A2 | solute carrier family 45, member 2 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SMOX | spermine oxidase |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPARCL1 | SPARC-like 1 (hevin) |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TLR2 | toll-like receptor 2 |
| TLR5 | toll-like receptor 5 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TRIM29 | tripartite motif containing 29 |
| UNC119 | unc-119 homolog (C. elegans) |
| VEGFA | vascular endothelial growth factor A |
| WDR33 | WD repeat domain 33 |
| WDR62 | WD repeat domain 62 |
| WSCD1 | WSC domain containing 1 |
| XYLB | xylulokinase homolog (H. influenzae) |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ANKRD40 | ankyrin repeat domain 40 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CXADR | coxsackie virus and adenovirus receptor |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| EFNA3 | ephrin-A3 |
| ELMO3 | engulfment and cell motility 3 |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPHA4 | EPH receptor A4 |
| FAM50B | family with sequence similarity 50, member B |
| FRAT1 | frequently rearranged in advanced T-cell lymphomas 1 |
| GAA | glucosidase, alpha; acid |
| GAS8 | growth arrest-specific 8 |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPR1 | G protein-coupled receptor 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HOXC10 | homeobox C10 |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IFT140 | intraflagellar transport 140 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| INO80D | INO80 complex subunit D |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KIAA0319L | KIAA0319-like |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MANBA | mannosidase, beta A, lysosomal |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MED15 | mediator complex subunit 15 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MON1B | MON1 secretory trafficking family member B |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| N4BP3 | NEDD4 binding protein 3 |
| NDE1 | nudE neurodevelopment protein 1 |
| NME5 | NME/NM23 family member 5 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PCDHB3 | protocadherin beta 3 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PGS1 | phosphatidylglycerophosphate synthase 1 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PITX2 | paired-like homeodomain 2 |
| PLA2G12A | phospholipase A2, group XIIA |
| PLXNA3 | plexin A3 |
| PMP22 | peripheral myelin protein 22 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| PVRL3 | poliovirus receptor-related 3 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RGS2 | regulator of G-protein signaling 2 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RNF2 | ring finger protein 2 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SIX1 | SIX homeobox 1 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLN | sarcolipin |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
| SNIP1 | Smad nuclear interacting protein 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SYCP2 | synaptonemal complex protein 2 |
| TCHH | trichohyalin |
| TEX40 | testis expressed 40 |
| TPCN1 | two pore segment channel 1 |
| TUBA4B | tubulin, alpha 4b |
| UNC13B | unc-13 homolog B (C. elegans) |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR91 | WD repeat domain 91 |
| ZMYM1 | zinc finger, MYM-type 1 |
| ZNF226 | zinc finger protein 226 |
| ZNF227 | zinc finger protein 227 |
| ZNF329 | zinc finger protein 329 |
| ZNF35 | zinc finger protein 35 |
| ZNF551 | zinc finger protein 551 |
| ZNF804A | zinc finger protein 804A |
| ZW10 | zw10 kinetochore protein |
