| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the prasterone-6474 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD6 | abhydrolase domain containing 6 |
| ACTN2 | actinin, alpha 2 |
| AIF1 | allograft inflammatory factor 1 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ANGPTL2 | angiopoietin-like 2 |
| AREG | amphiregulin |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ARTN | artemin |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP10B | ATPase, class V, type 10B |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BMP1 | bone morphogenetic protein 1 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CD84 | CD84 molecule |
| CDK18 | cyclin-dependent kinase 18 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLGN | calmegin |
| CLIP1 | CAP-GLY domain containing linker protein 1 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COMT | catechol-O-methyltransferase |
| CRMP1 | collapsin response mediator protein 1 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CUL2 | cullin 2 |
| CYHR1 | cysteine/histidine-rich 1 |
| DCAF11 | DDB1 and CUL4 associated factor 11 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| EGR3 | early growth response 3 |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FPR3 | formyl peptide receptor 3 |
| GALC | galactosylceramidase |
| GRIP2 | glutamate receptor interacting protein 2 |
| HBS1L | HBS1-like translational GTPase |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HMOX1 | heme oxygenase 1 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| INHBE | inhibin, beta E |
| INSIG1 | insulin induced gene 1 |
| KAZN | kazrin, periplakin interacting protein |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LRRN3 | leucine rich repeat neuronal 3 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAGEA8 | melanoma antigen family A8 |
| MAL | mal, T-cell differentiation protein |
| MANBA | mannosidase, beta A, lysosomal |
| MAP2K2 | mitogen-activated protein kinase kinase 2 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MAPT | microtubule-associated protein tau |
| MVD | mevalonate (diphospho) decarboxylase |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NF1 | neurofibromin 1 |
| NKX3-2 | NK3 homeobox 2 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NSUN7 | NOP2/Sun domain family, member 7 |
| NUDT7 | nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
| NUP98 | nucleoporin 98kDa |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PARVA | parvin, alpha |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PITX1 | paired-like homeodomain 1 |
| POPDC3 | popeye domain containing 3 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTHLH | parathyroid hormone-like hormone |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| QSER1 | glutamine and serine rich 1 |
| S100A8 | S100 calcium binding protein A8 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGSM3 | small G protein signaling modulator 3 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SOS1 | son of sevenless homolog 1 (Drosophila) |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TGM2 | transglutaminase 2 |
| TMEM120B | transmembrane protein 120B |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRADD | TNFRSF1A-associated via death domain |
| TRIM2 | tripartite motif containing 2 |
| TRIM36 | tripartite motif containing 36 |
| TTC38 | tetratricopeptide repeat domain 38 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ADAM2 | ADAM metallopeptidase domain 2 |
| ADM | adrenomedullin |
| APBA3 | amyloid beta (A4) precursor protein-binding, family A, member 3 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ASPN | asporin |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCNT1 | cyclin T1 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CIDEC | cell death-inducing DFFA-like effector c |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CLDN17 | claudin 17 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM155A | family with sequence similarity 155, member A |
| FAM186A | family with sequence similarity 186, member A |
| FBXO31 | F-box protein 31 |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GRPR | gastrin-releasing peptide receptor |
| HCFC2 | host cell factor C2 |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H3I | histone cluster 1, H3i |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IPO8 | importin 8 |
| KIAA1456 | KIAA1456 |
| LHX1 | LIM homeobox 1 |
| LOC100131532 | uncharacterized LOC100131532 |
| LRRC61 | leucine rich repeat containing 61 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MED31 | mediator complex subunit 31 |
| MPI | mannose phosphate isomerase |
| MYO1F | myosin IF |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NLGN1 | neuroligin 1 |
| NLRX1 | NLR family member X1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NRSN2 | neurensin 2 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PADI1 | peptidyl arginine deiminase, type I |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRDM14 | PR domain containing 14 |
| PROL1 | proline rich, lacrimal 1 |
| PRSS50 | protease, serine, 50 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RAPSN | receptor-associated protein of the synapse |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SECTM1 | secreted and transmembrane 1 |
| SFRP5 | secreted frizzled-related protein 5 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TIGD6 | tigger transposable element derived 6 |
| TMEM209 | transmembrane protein 209 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TRABD | TraB domain containing |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TSPAN1 | tetraspanin 1 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBB2B | tubulin, beta 2B class IIb |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| URM1 | ubiquitin related modifier 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| WDR4 | WD repeat domain 4 |
| WDR62 | WD repeat domain 62 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF506 | zinc finger protein 506 |
