| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the prasterone-6673 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACRV1 | acrosomal vesicle protein 1 |
| ADAM11 | ADAM metallopeptidase domain 11 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ARHGAP28 | Rho GTPase activating protein 28 |
| AURKC | aurora kinase C |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCO1 | beta-carotene oxygenase 1 |
| BMP4 | bone morphogenetic protein 4 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCNO | cyclin O |
| CD160 | CD160 molecule |
| CDC14B | cell division cycle 14B |
| CHML | choroideremia-like (Rab escort protein 2) |
| COL14A1 | collagen, type XIV, alpha 1 |
| COL5A1 | collagen, type V, alpha 1 |
| CRHR1 | corticotropin releasing hormone receptor 1 |
| CTSZ | cathepsin Z |
| CWH43 | cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B |
| FBXO40 | F-box protein 40 |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| FZD10 | frizzled class receptor 10 |
| FZD9 | frizzled class receptor 9 |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| HMOX1 | heme oxygenase 1 |
| ICAM1 | intercellular adhesion molecule 1 |
| IGSF6 | immunoglobulin superfamily, member 6 |
| ING4 | inhibitor of growth family, member 4 |
| IZUMO4 | IZUMO family member 4 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIF25 | kinesin family member 25 |
| KRT33A | keratin 33A, type I |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NEK9 | NIMA-related kinase 9 |
| NOX1 | NADPH oxidase 1 |
| NRXN2 | neurexin 2 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PCP4 | Purkinje cell protein 4 |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PFDN6 | prefoldin subunit 6 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PKP1 | plakophilin 1 |
| PLEK | pleckstrin |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PVR | poliovirus receptor |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASAL2 | RAS protein activator like 2 |
| RB1 | retinoblastoma 1 |
| RPL13 | ribosomal protein L13 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SFRP4 | secreted frizzled-related protein 4 |
| SIRT4 | sirtuin 4 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SMAD6 | SMAD family member 6 |
| SPON1 | spondin 1, extracellular matrix protein |
| SPPL2B | signal peptide peptidase like 2B |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| STK4 | serine/threonine kinase 4 |
| TFDP3 | transcription factor Dp family, member 3 |
| THOC5 | THO complex 5 |
| TJP3 | tight junction protein 3 |
| TLK1 | tousled-like kinase 1 |
| TLL1 | tolloid-like 1 |
| TM6SF2 | transmembrane 6 superfamily member 2 |
| TMEM63A | transmembrane protein 63A |
| TMPRSS6 | transmembrane protease, serine 6 |
| TPM3 | tropomyosin 3 |
| TRIM49 | tripartite motif containing 49 |
| TXNRD2 | thioredoxin reductase 2 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZNF225 | zinc finger protein 225 |
| ZNF24 | zinc finger protein 24 |
| ZNF573 | zinc finger protein 573 |
| Symbol | Name |
|---|---|
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BCOR | BCL6 corepressor |
| BMP15 | bone morphogenetic protein 15 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC88C | coiled-coil domain containing 88C |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDIP1 | cell death-inducing p53 target 1 |
| CPNE7 | copine VII |
| CTC1 | CTS telomere maintenance complex component 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DLL3 | delta-like 3 (Drosophila) |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERF | Ets2 repressor factor |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FBRS | fibrosin |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GALK1 | galactokinase 1 |
| GMPR | guanosine monophosphate reductase |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPC3 | glypican 3 |
| GRAMD1C | GRAM domain containing 1C |
| H2AFJ | H2A histone family, member J |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H4E | histone cluster 1, H4e |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXA2 | homeobox A2 |
| HOXA4 | homeobox A4 |
| HOXC10 | homeobox C10 |
| HOXC8 | homeobox C8 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| IFT54 | intraflagellar transport 54 |
| IL17RA | interleukin 17 receptor A |
| KIAA0895 | KIAA0895 |
| KLHL28 | kelch-like family member 28 |
| KLK7 | kallikrein-related peptidase 7 |
| KRT37 | keratin 37, type I |
| LAMC3 | laminin, gamma 3 |
| LOC730101 | uncharacterized LOC730101 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MTSS1L | metastasis suppressor 1-like |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| MYO1D | myosin ID |
| MYO1F | myosin IF |
| NUPL2 | nucleoporin like 2 |
| OLFML2A | olfactomedin-like 2A |
| OLFML3 | olfactomedin-like 3 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PLXNB3 | plexin B3 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| RAB40A | RAB40A, member RAS oncogene family |
| RPH3A | rabphilin 3A |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SETD1B | SET domain containing 1B |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| STAG3 | stromal antigen 3 |
| TCTN2 | tectonic family member 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THBS3 | thrombospondin 3 |
| TMEM209 | transmembrane protein 209 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TTC30A | tetratricopeptide repeat domain 30A |
| TUBA4B | tubulin, alpha 4b |
| VEGFB | vascular endothelial growth factor B |
| VGF | VGF nerve growth factor inducible |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZNF264 | zinc finger protein 264 |
| ZNF391 | zinc finger protein 391 |
| ZNF426 | zinc finger protein 426 |
| ZNF611 | zinc finger protein 611 |
| ZNF76 | zinc finger protein 76 |
