pravastatin-lactone Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
Similar Terms
Downloads & Tools

Genes

666 genes differentially expressed following the pravastatin-lactone small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
DYNLT3 dynein, light chain, Tctex-type 3 17.0806
CEP57 centrosomal protein 57kDa 13.6855
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 10.4275
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 8.7283
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 7.97002
MAMLD1 mastermind-like domain containing 1 7.4102
CST8 cystatin 8 (cystatin-related epididymal specific) 6.35053
FSD1 fibronectin type III and SPRY domain containing 1 6.23747
TIAM1 T-cell lymphoma invasion and metastasis 1 5.94467
SCARA3 scavenger receptor class A, member 3 5.84938
FEV FEV (ETS oncogene family) 5.76203
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 5.67074
RPS4Y1 ribosomal protein S4, Y-linked 1 5.59747
CCNB2 cyclin B2 5.58857
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 5.53511
LRRN3 leucine rich repeat neuronal 3 5.46439
RRAS2 related RAS viral (r-ras) oncogene homolog 2 5.33151
UMOD uromodulin 5.29154
FGFR4 fibroblast growth factor receptor 4 5.28046
CADM3-AS1 CADM3 antisense RNA 1 5.21372
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 5.16746
UBFD1 ubiquitin family domain containing 1 5.08159
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 5.03489
AQP2 aquaporin 2 (collecting duct) 4.95532
HEG1 heart development protein with EGF-like domains 1 4.92685
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 4.89467
PTPRN protein tyrosine phosphatase, receptor type, N 4.87932
KIF23 kinesin family member 23 4.87245
RAMP3 receptor (G protein-coupled) activity modifying protein 3 4.84064
STAB2 stabilin 2 4.7381
CHAT choline O-acetyltransferase 4.71001
ATRN attractin 4.6962
TSHZ2 teashirt zinc finger homeobox 2 4.69439
CETN2 centrin, EF-hand protein, 2 4.64008
SHCBP1 SHC SH2-domain binding protein 1 4.63954
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 4.61746
ALDOB aldolase B, fructose-bisphosphate 4.59928
CXCL12 chemokine (C-X-C motif) ligand 12 4.59724
NSD3 nuclear receptor binding SET domain protein 3 4.58907
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 4.58716
GPR6 G protein-coupled receptor 6 4.56923
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 4.55319
SP140 SP140 nuclear body protein 4.4419
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 4.43471
CARHSP1 calcium regulated heat stable protein 1, 24kDa 4.43023
RBM4 RNA binding motif protein 4 4.42953
C14ORF132 chromosome 14 open reading frame 132 4.3967
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 4.38651
TSPYL4 TSPY-like 4 4.37852
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 4.37136
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 4.31814
TTC22 tetratricopeptide repeat domain 22 4.30913
ARPP19 cAMP-regulated phosphoprotein, 19kDa 4.27406
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 4.27335
C1ORF105 chromosome 1 open reading frame 105 4.27148
C7 complement component 7 4.27024
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8 4.26034
CALB1 calbindin 1, 28kDa 4.25614
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 4.21106
WDR48 WD repeat domain 48 4.19887
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 4.19147
GVINP1 GTPase, very large interferon inducible pseudogene 1 4.17199
GATD3 glutamine amidotransferase class 1 domain containing 3 4.15875
FBLN5 fibulin 5 4.15253
SCN2B sodium channel, voltage gated, type II beta subunit 4.14942
LIMD1 LIM domains containing 1 4.14896
FCN3 ficolin (collagen/fibrinogen domain containing) 3 4.14706
MTMR2 myotubularin related protein 2 4.14158
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 4.13094
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 4.12916
ARSF arylsulfatase F 4.12381
FYCO1 FYVE and coiled-coil domain containing 1 4.11643
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 4.10991
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 4.0828
PYY peptide YY 4.07472
JAM2 junctional adhesion molecule 2 4.06921
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 4.06358
IKZF1 IKAROS family zinc finger 1 (Ikaros) 4.06319
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 4.05248
MNMIP1 manchette microtubule inner protein 1 4.05023
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 4.01778
PNPLA3 patatin-like phospholipase domain containing 3 4.00391
SP110 SP110 nuclear body protein 3.9983
C2CD5 C2 calcium-dependent domain containing 5 3.99429
ERG28 ergosterol biosynthesis 28 homolog 3.98284
WNT10B wingless-type MMTV integration site family, member 10B 3.95071
HAO2 hydroxyacid oxidase 2 (long chain) 3.94168
C11ORF16 chromosome 11 open reading frame 16 3.93406
AGO2 argonaute RISC catalytic component 2 3.93048
HIRIP3 HIRA interacting protein 3 3.90334
STARD8 StAR-related lipid transfer (START) domain containing 8 3.90056
CRNKL1 crooked neck pre-mRNA splicing factor 1 3.87886
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 3.87683
FAM171A1 family with sequence similarity 171, member A1 3.87255
KDM3A lysine (K)-specific demethylase 3A 3.87014
SERGEF secretion regulating guanine nucleotide exchange factor 3.86597
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 3.8596
IQCG IQ motif containing G 3.8563
AHI1 Abelson helper integration site 1 3.85493
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 3.84569
RAD51AP1 RAD51 associated protein 1 3.84529
IL3RA interleukin 3 receptor, alpha (low affinity) 3.82617
TMSB10 thymosin beta 10 3.82082
ZNF134 zinc finger protein 134 3.81264
SNAP25 synaptosomal-associated protein, 25kDa 3.80648
ACAA2 acetyl-CoA acyltransferase 2 3.80208
SLC14A2 solute carrier family 14 (urea transporter), member 2 3.79981
IDS iduronate 2-sulfatase 3.79468
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 3.79432
DHCR24 24-dehydrocholesterol reductase 3.79224
NDNF neuron-derived neurotrophic factor 3.79162
PSMC3IP PSMC3 interacting protein 3.77919
SCNN1B sodium channel, non voltage gated 1 beta subunit 3.77221
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 3.7692
EPS8L1 EPS8-like 1 3.76189
THTPA thiamine triphosphatase 3.75782
IGFALS insulin-like growth factor binding protein, acid labile subunit 3.75396
PTH1R parathyroid hormone 1 receptor 3.74855
LPAR3 lysophosphatidic acid receptor 3 3.74291
TRIM46 tripartite motif containing 46 3.72944
CISH cytokine inducible SH2-containing protein 3.72461
EPAS1 endothelial PAS domain protein 1 3.72119
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 3.71742
BDH2 3-hydroxybutyrate dehydrogenase, type 2 3.71604
PDE2A phosphodiesterase 2A, cGMP-stimulated 3.71531
DCAF4 DDB1 and CUL4 associated factor 4 3.71284
CAMKV CaM kinase-like vesicle-associated 3.71071
CHTOP chromatin target of PRMT1 3.7031
DDN dendrin 3.69871
DPEP1 dipeptidase 1 (renal) 3.6973
VGF VGF nerve growth factor inducible 3.69718
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 3.69525
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 3.68573
LZTS1 leucine zipper, putative tumor suppressor 1 3.68354
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 3.6789
KRT76 keratin 76, type II 3.6491
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 3.63064
KIF15 kinesin family member 15 3.62802
LDB2 LIM domain binding 2 3.62607
MSMO1 methylsterol monooxygenase 1 3.6198
IL21R interleukin 21 receptor 3.61973
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 3.61091
INHBC inhibin, beta C 3.60998
DDO D-aspartate oxidase 3.60544
DBT dihydrolipoamide branched chain transacylase E2 3.60245
B9D2 B9 protein domain 2 3.59933
CUBN cubilin (intrinsic factor-cobalamin receptor) 3.59487
ASB1 ankyrin repeat and SOCS box containing 1 3.5947
SRCAP Snf2-related CREBBP activator protein 3.58352
CENPBD2P CENPB DNA-binding domains containing 2, pseudogene 3.57569
MED17 mediator complex subunit 17 3.57339
GSTZ1 glutathione S-transferase zeta 1 3.56897
QDPR quinoid dihydropteridine reductase 3.56437
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 3.55417
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 3.54302
FXYD6 FXYD domain containing ion transport regulator 6 3.53917
YME1L1 YME1-like 1 ATPase 3.5321
RABGAP1 RAB GTPase activating protein 1 3.52881
AFF1 AF4/FMR2 family, member 1 3.52115
UNC119B unc-119 homolog B (C. elegans) 3.51317
PASK PAS domain containing serine/threonine kinase 3.50841
PTPRO protein tyrosine phosphatase, receptor type, O 3.50596
FAM110D family with sequence similarity 110, member D 3.50345
ABAT 4-aminobutyrate aminotransferase 3.49289
CD48 CD48 molecule 3.49129
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 3.48998
KIF11 kinesin family member 11 3.48958
RHOBTB2 Rho-related BTB domain containing 2 3.47978
ITCH itchy E3 ubiquitin protein ligase 3.4754
CSNK2A1 casein kinase 2, alpha 1 polypeptide 3.47535
GJC1 gap junction protein, gamma 1, 45kDa 3.47381
GDF2 growth differentiation factor 2 3.47119
ANXA13 annexin A13 3.46928
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 3.4652
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 3.46374
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 3.46278
GGT5 gamma-glutamyltransferase 5 3.45826
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) 3.45505
DPP6 dipeptidyl-peptidase 6 3.45109
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.44854
LPIN1 lipin 1 3.44529
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 3.44313
FGF21 fibroblast growth factor 21 3.44149
F11 coagulation factor XI 3.43985
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 3.43345
ZNF197 zinc finger protein 197 3.42941
MLH1 mutL homolog 1 3.42816
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 3.42641
DNASE1L3 deoxyribonuclease I-like 3 3.42533
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 3.42419
DENND6B DENN/MADD domain containing 6B 3.4209
FDPS farnesyl diphosphate synthase 3.41714
DNAAF11 dynein axonemal assembly factor 11 3.41347
GCHFR GTP cyclohydrolase I feedback regulator 3.40893
PAIP1 poly(A) binding protein interacting protein 1 3.40889
SPEF1 sperm flagellar 1 3.40882
ZMYND10 zinc finger, MYND-type containing 10 3.40803
PIERCE1 piercer of microtubule wall 1 3.40614
UPK1B uroplakin 1B 3.40601
CCL21 chemokine (C-C motif) ligand 21 3.40248
CLEC2D C-type lectin domain family 2, member D 3.39575
EDA ectodysplasin A 3.38609
ADAR adenosine deaminase, RNA-specific 3.38444
ESR2 estrogen receptor 2 (ER beta) 3.38351
SLIT2 slit homolog 2 (Drosophila) 3.3826
TMEM53 transmembrane protein 53 3.38143
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 3.37961
TULP4 tubby like protein 4 3.3713
HYAL2 hyaluronoglucosaminidase 2 3.37025
FBXL2 F-box and leucine-rich repeat protein 2 3.36637
STRA6 stimulated by retinoic acid 6 3.36449
CTF1 cardiotrophin 1 3.34393
LY9 lymphocyte antigen 9 3.33993
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 3.33927
RARB retinoic acid receptor, beta 3.33809
NCS1 neuronal calcium sensor 1 3.33791
GCH1 GTP cyclohydrolase 1 3.33734
GATA6 GATA binding protein 6 3.33594
DYNC2I1 dynein 2 intermediate chain 1 3.3337
PPP1R7 protein phosphatase 1, regulatory subunit 7 3.32616
GFOD2 glucose-fructose oxidoreductase domain containing 2 3.31547
PRLH prolactin releasing hormone 3.3045
SV2C synaptic vesicle glycoprotein 2C 3.29958
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 3.29469
OCA2 oculocutaneous albinism II 3.28916
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 3.28893
SH3BP1 SH3-domain binding protein 1 3.28816
SEC23B Sec23 homolog B (S. cerevisiae) 3.28809
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 3.28393
RAB3B RAB3B, member RAS oncogene family 3.28165
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 3.27045
MED31 mediator complex subunit 31 3.26774
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 3.26746
CFDP1 craniofacial development protein 1 3.26143
OGDHL oxoglutarate dehydrogenase-like 3.25748
BMAL1 basic helix-loop-helix ARNT like 1 3.25649
CD5 CD5 molecule 3.25022
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 3.24191
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 3.23885
CNR2 cannabinoid receptor 2 (macrophage) 3.22265
RNF167 ring finger protein 167 3.22021
CTRC chymotrypsin C (caldecrin) 3.21748
EMD emerin 3.21498
ENG endoglin 3.21481
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 3.21416
TOX thymocyte selection-associated high mobility group box 3.21348
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 3.21084
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 3.20832
RABGGTB Rab geranylgeranyltransferase, beta subunit 3.20727
GDF5 growth differentiation factor 5 3.20564
MLF2 myeloid leukemia factor 2 3.2008
AIRE autoimmune regulator 3.20017
CD40LG CD40 ligand 3.19932
OR1D2 olfactory receptor, family 1, subfamily D, member 2 3.19652
PRAMEF11 PRAME family member 11 3.19293
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 3.19238
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 3.19103
SPAG16 sperm associated antigen 16 3.19003
JCAD junctional cadherin 5 associated 3.18447
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 3.17228
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 3.16975
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 3.16504
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 3.15347
SMC6 structural maintenance of chromosomes 6 3.15035
RDH8 retinol dehydrogenase 8 (all-trans) 3.14445
TBC1D2B TBC1 domain family, member 2B 3.14392
SRSF5 serine/arginine-rich splicing factor 5 3.14149
OARD1 O-acyl-ADP-ribose deacylase 1 3.13729
NECAB2 N-terminal EF-hand calcium binding protein 2 3.13533
GAPVD1 GTPase activating protein and VPS9 domains 1 3.13119
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) 3.12657
RAB11FIP1 RAB11 family interacting protein 1 (class I) 3.12623
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 3.12432
NCAPG non-SMC condensin I complex, subunit G 3.12241
CLU clusterin 3.12221
SHMT1 serine hydroxymethyltransferase 1 (soluble) 3.11663
ESRP2 epithelial splicing regulatory protein 2 3.11472
NKAIN1 Na+/K+ transporting ATPase interacting 1 3.11454
EIF3L eukaryotic translation initiation factor 3, subunit L 3.11102
HYAL4 hyaluronoglucosaminidase 4 3.10976
ARF6 ADP-ribosylation factor 6 3.10887
AKAP5 A kinase (PRKA) anchor protein 5 3.10886
UNC13A unc-13 homolog A (C. elegans) 3.10642
PRPS2 phosphoribosyl pyrophosphate synthetase 2 3.10608
LAMC3 laminin, gamma 3 3.10583
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 3.10276
SMCO4 single-pass membrane protein with coiled-coil domains 4 3.09738
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 3.09671
KHK ketohexokinase (fructokinase) 3.09658
DDRGK1 DDRGK domain containing 1 3.09597
KIF18A kinesin family member 18A 3.09587
MSL3 male-specific lethal 3 homolog (Drosophila) 3.09577
VIM vimentin 3.09376
MEPE matrix extracellular phosphoglycoprotein 3.08616
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 3.08584
RPP14 ribonuclease P/MRP 14kDa subunit 3.0818
CLPS colipase, pancreatic 3.07936
IK IK cytokine, down-regulator of HLA II 3.07761
BBOF1 basal body orientation factor 1 3.07697
THY1 Thy-1 cell surface antigen 3.07513
CES1 carboxylesterase 1 3.07158
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 3.06136
ECE2 endothelin converting enzyme 2 3.05866
KNG1 kininogen 1 3.05672
CD4 CD4 molecule 3.05671
TACC1 transforming, acidic coiled-coil containing protein 1 3.05394
AGRP agouti related neuropeptide 3.04111
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 3.03862
BGN biglycan 3.03739
SLA Src-like-adaptor 3.03463
C5ORF22 chromosome 5 open reading frame 22 3.03297
TSPAN4 tetraspanin 4 3.0318
EIF3F eukaryotic translation initiation factor 3, subunit F 3.0298
SH2D3C SH2 domain containing 3C 3.02859
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 3.02723
DNAI1 dynein, axonemal, intermediate chain 1 3.02582
GLRA2 glycine receptor, alpha 2 3.02193
SYT2 synaptotagmin II 3.0208
PDE4C phosphodiesterase 4C, cAMP-specific 3.01709
SCUBE3 signal peptide, CUB domain, EGF-like 3 3.00799
TSPAN31 tetraspanin 31 3.00732
RPL37 ribosomal protein L37 3.00663
PGLYRP4 peptidoglycan recognition protein 4 3.00293
AFM afamin 3.00101

decreased expression

Symbol Name Standardized Value
CCDC86 coiled-coil domain containing 86 -9.14199
CYCS cytochrome c, somatic -6.56509
NUSAP1 nucleolar and spindle associated protein 1 -5.81398
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -5.69697
PPARG peroxisome proliferator-activated receptor gamma -5.54966
MMP28 matrix metallopeptidase 28 -5.53168
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 -5.42306
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) -5.34073
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -5.29353
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -5.23417
CDC20 cell division cycle 20 -5.20426
CXCL5 chemokine (C-X-C motif) ligand 5 -5.15326
DIRAS2 DIRAS family, GTP-binding RAS-like 2 -5.15277
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -5.1482
NEB nebulin -5.08808
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -4.97505
LAMB3 laminin, beta 3 -4.96498
WASHC4 WASH complex subunit 4 -4.94674
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit -4.92868
SV2B synaptic vesicle glycoprotein 2B -4.90846
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 -4.90127
GARNL3 GTPase activating Rap/RanGAP domain-like 3 -4.80561
EVI5 ecotropic viral integration site 5 -4.80517
EN1 engrailed homeobox 1 -4.79711
TRPV2 transient receptor potential cation channel, subfamily V, member 2 -4.75712
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -4.74576
TEX41 testis expressed 41 (non-protein coding) -4.70385
CCL27 chemokine (C-C motif) ligand 27 -4.65442
CSAD cysteine sulfinic acid decarboxylase -4.64238
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 -4.62608
ESM1 endothelial cell-specific molecule 1 -4.62424
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 -4.58851
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.55965
PTGDR2 prostaglandin D2 receptor 2 -4.54156
COTL1 coactosin-like F-actin binding protein 1 -4.52272
EBF2 early B-cell factor 2 -4.51246
CD40 CD40 molecule, TNF receptor superfamily member 5 -4.50122
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 -4.48953
POU4F2 POU class 4 homeobox 2 -4.48856
KALRN kalirin, RhoGEF kinase -4.48655
HEBP2 heme binding protein 2 -4.46621
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 -4.45923
ZDHHC3 zinc finger, DHHC-type containing 3 -4.4582
GYPE glycophorin E (MNS blood group) -4.44629
RETREG1 reticulophagy regulator 1 -4.44257
B3GAT3 beta-1,3-glucuronyltransferase 3 -4.43485
TMEM258 transmembrane protein 258 -4.42515
MMP27 matrix metallopeptidase 27 -4.41744
GLRA3 glycine receptor, alpha 3 -4.41315
SLC30A10 solute carrier family 30, member 10 -4.35928
MINAR1 membrane integral NOTCH2 associated receptor 1 -4.35349
ACOXL acyl-CoA oxidase-like -4.34486
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 -4.34431
SPTBN5 spectrin, beta, non-erythrocytic 5 -4.34153
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 -4.32283
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) -4.26547
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -4.26336
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -4.2176
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -4.19176
ARHGAP6 Rho GTPase activating protein 6 -4.17496
SPON2 spondin 2, extracellular matrix protein -4.13677
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -4.13569
LRRC31 leucine rich repeat containing 31 -4.13323
TNMD tenomodulin -4.10763
PCDHGB6 protocadherin gamma subfamily B, 6 -4.10482
CNGB1 cyclic nucleotide gated channel beta 1 -4.07189
AMOT angiomotin -4.06699
APIP APAF1 interacting protein -4.06339
USH2A Usher syndrome 2A (autosomal recessive, mild) -4.05906
MORC1 MORC family CW-type zinc finger 1 -4.05826
TBCA tubulin folding cofactor A -4.04847
NID2 nidogen 2 (osteonidogen) -4.04674
LAMA4 laminin, alpha 4 -4.03712
ZNF407 zinc finger protein 407 -4.0348
KIF2A kinesin heavy chain member 2A -4.03394
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -4.02862
DDB1 damage-specific DNA binding protein 1, 127kDa -4.02607
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -4.02098
FAM135A family with sequence similarity 135, member A -4.00267
ZNF674 zinc finger protein 674 -3.99589
LHCGR luteinizing hormone/choriogonadotropin receptor -3.99521
GPR4 G protein-coupled receptor 4 -3.99409
ZNF460 zinc finger protein 460 -3.98318
POU1F1 POU class 1 homeobox 1 -3.95905
CNOT2 CCR4-NOT transcription complex, subunit 2 -3.95287
TTBK2 tau tubulin kinase 2 -3.94582
RFPL1S RFPL1 antisense RNA 1 -3.94403
ADRM1 adhesion regulating molecule 1 -3.93586
PUS1 pseudouridylate synthase 1 -3.92739
TPTE transmembrane phosphatase with tensin homology -3.92373
AGBL3 ATP/GTP binding protein-like 3 -3.92047
NOP10 NOP10 ribonucleoprotein -3.91926
LRRC1 leucine rich repeat containing 1 -3.88637
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) -3.88158
OLAH oleoyl-ACP hydrolase -3.87777
ENPEP glutamyl aminopeptidase (aminopeptidase A) -3.87058
TYMS thymidylate synthetase -3.85641
KLF8 Kruppel-like factor 8 -3.85019
TRIM58 tripartite motif containing 58 -3.84902
ANGPTL4 angiopoietin-like 4 -3.83879
SOX5 SRY (sex determining region Y)-box 5 -3.83348
DCHS1 dachsous cadherin-related 1 -3.83085
ZNRD2 zinc ribbon domain containing 2 -3.8119
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.80944
NFE2 nuclear factor, erythroid 2 -3.80513
BHMT2 betaine--homocysteine S-methyltransferase 2 -3.79343
HPGDS hematopoietic prostaglandin D synthase -3.79263
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 -3.77877
UBA5 ubiquitin-like modifier activating enzyme 5 -3.77151
CDHR1 cadherin-related family member 1 -3.76836
OR2B6 olfactory receptor, family 2, subfamily B, member 6 -3.7614
MRPS2 mitochondrial ribosomal protein S2 -3.7591
ANKRD36BP2 ankyrin repeat domain 36B pseudogene 2 -3.75235
TEX12 testis expressed 12 -3.75139
PPP4R4 protein phosphatase 4, regulatory subunit 4 -3.75091
MSTN myostatin -3.7354
CRYBA1 crystallin, beta A1 -3.73037
LIN7A lin-7 homolog A (C. elegans) -3.7284
GDF15 growth differentiation factor 15 -3.72554
TBC1D8B TBC1 domain family, member 8B (with GRAM domain) -3.72174
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -3.71777
WDR41 WD repeat domain 41 -3.71424
SSX1 synovial sarcoma, X breakpoint 1 -3.70317
FES FES proto-oncogene, tyrosine kinase -3.6994
KNL1 kinetochore scaffold 1 -3.69808
COLGALT2 collagen beta(1-O)galactosyltransferase 2 -3.69444
ARL15 ADP-ribosylation factor-like 15 -3.69243
ANGPTL2 angiopoietin-like 2 -3.69037
PDHX pyruvate dehydrogenase complex, component X -3.6792
RIPPLY3 ripply transcriptional repressor 3 -3.67676
LAD1 ladinin 1 -3.67459
RFPL1 ret finger protein-like 1 -3.6646
PRKG1 protein kinase, cGMP-dependent, type I -3.65827
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -3.65372
CLCA3P chloride channel accessory 3, pseudogene -3.63585
KLF3-AS1 KLF3 antisense RNA 1 -3.62744
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 -3.62229
GFM1 G elongation factor, mitochondrial 1 -3.6172
HBD hemoglobin, delta -3.61138
NSUN5 NOP2/Sun domain family, member 5 -3.61037
STK3 serine/threonine kinase 3 -3.60579
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 -3.601
CSN2 casein beta -3.58881
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 -3.58828
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -3.5829
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) -3.57697
SLC25A30 solute carrier family 25, member 30 -3.57296
ASPA aspartoacylase -3.56133
ZFPM2 zinc finger protein, FOG family member 2 -3.55971
AVPR1A arginine vasopressin receptor 1A -3.55837
PIEZO1 piezo-type mechanosensitive ion channel component 1 -3.53788
ADAM2 ADAM metallopeptidase domain 2 -3.53489
ACAD8 acyl-CoA dehydrogenase family, member 8 -3.533
S100B S100 calcium binding protein B -3.53074
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa -3.52957
NUP43 nucleoporin 43kDa -3.51796
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -3.51599
E2F2 E2F transcription factor 2 -3.51289
NSUN6 NOP2/Sun domain family, member 6 -3.51057
SMAD5-AS1 SMAD5 antisense RNA 1 -3.5075
H2AX H2A.X variant histone -3.50714
RALBP1 ralA binding protein 1 -3.50609
ADRA1B adrenoceptor alpha 1B -3.50551
PRC1 protein regulator of cytokinesis 1 -3.50278
ZNF280D zinc finger protein 280D -3.50083
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 -3.49894
CYB5R2 cytochrome b5 reductase 2 -3.49603
CCDC68 coiled-coil domain containing 68 -3.48998
CLCA4 chloride channel accessory 4 -3.48095
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 -3.47964
FGF18 fibroblast growth factor 18 -3.47732
RUBCNL rubicon like autophagy enhancer -3.47481
CLTB clathrin, light chain B -3.47409
PF4V1 platelet factor 4 variant 1 -3.47038
CPPED1 calcineurin-like phosphoesterase domain containing 1 -3.46922
TMC7 transmembrane channel-like 7 -3.46684
TMOD2 tropomodulin 2 (neuronal) -3.45938
FSCN1 fascin actin-bundling protein 1 -3.45034
EIF3B eukaryotic translation initiation factor 3, subunit B -3.449
U2SURP U2 snRNP-associated SURP domain containing -3.44746
MTF2 metal response element binding transcription factor 2 -3.43848
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B -3.43378
TAOK3 TAO kinase 3 -3.42721
GNRHR gonadotropin-releasing hormone receptor -3.42718
PPIF peptidylprolyl isomerase F -3.42236
KRT1 keratin 1, type II -3.42045
ESRRA estrogen-related receptor alpha -3.4153
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa -3.41476
MEOX2 mesenchyme homeobox 2 -3.40774
OR1A2 olfactory receptor, family 1, subfamily A, member 2 -3.40487
TRPM4 transient receptor potential cation channel, subfamily M, member 4 -3.40428
NT5M 5',3'-nucleotidase, mitochondrial -3.40355
DYM dymeclin -3.39552
HSDL2 hydroxysteroid dehydrogenase like 2 -3.39262
ZNF780B zinc finger protein 780B -3.38716
SHOX short stature homeobox -3.38675
PMP2 peripheral myelin protein 2 -3.38573
PROCR protein C receptor, endothelial -3.38369
COX7C cytochrome c oxidase subunit VIIc -3.38259
CALCB calcitonin-related polypeptide beta -3.37894
REPS2 RALBP1 associated Eps domain containing 2 -3.37778
RARS2 arginyl-tRNA synthetase 2, mitochondrial -3.3741
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -3.36392
RAB40AL RAB40A, member RAS oncogene family-like -3.35754
ANKRD53 ankyrin repeat domain 53 -3.35233
GJB3 gap junction protein, beta 3, 31kDa -3.34753
DENR density-regulated protein -3.34706
PRCC papillary renal cell carcinoma (translocation-associated) -3.34435
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) -3.32356
ACKR3 atypical chemokine receptor 3 -3.32353
IFNW1 interferon, omega 1 -3.32324
ANKRD34C ankyrin repeat domain 34C -3.31015
RPN2 ribophorin II -3.30639
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 -3.29674
MATN3 matrilin 3 -3.2932
SPIN2A spindlin family, member 2A -3.29061
PLEKHS1 pleckstrin homology domain containing, family S member 1 -3.28963
MCOLN3 mucolipin 3 -3.28877
BRMS1 breast cancer metastasis suppressor 1 -3.28132
ASMTL-AS1 ASMTL antisense RNA 1 -3.28129
DPY19L1P1 DPY19L1 pseudogene 1 -3.27879
SOS1 son of sevenless homolog 1 (Drosophila) -3.27403
SERF2 small EDRK-rich factor 2 -3.27363
DESI1 desumoylating isopeptidase 1 -3.27105
LAMB4 laminin, beta 4 -3.26974
MYO16 myosin XVI -3.26891
ANPEP alanyl (membrane) aminopeptidase -3.26413
COX17 COX17 cytochrome c oxidase copper chaperone -3.25936
PTTG2 pituitary tumor-transforming 2 -3.25725
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 -3.24945
FSCN2 fascin actin-bundling protein 2, retinal -3.24371
IL13RA2 interleukin 13 receptor, alpha 2 -3.2416
RNF186 ring finger protein 186 -3.23968
UPK3A uroplakin 3A -3.23857
CHKA choline kinase alpha -3.23422
AKAP12 A kinase (PRKA) anchor protein 12 -3.23237
HSPA8 heat shock 70kDa protein 8 -3.23061
ZNF492 zinc finger protein 492 -3.23034
MAGEB3 melanoma antigen family B3 -3.22475
ZNF157 zinc finger protein 157 -3.22378
ANGPT2 angiopoietin 2 -3.22275
PAX4 paired box 4 -3.21666
SRM spermidine synthase -3.21654
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -3.21327
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -3.20902
CCPG1 cell cycle progression 1 -3.20794
CDA cytidine deaminase -3.20758
TRPC6 transient receptor potential cation channel, subfamily C, member 6 -3.20664
CA2 carbonic anhydrase II -3.20526
TSHB thyroid stimulating hormone, beta -3.20504
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 -3.20397
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1 -3.20199
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha -3.20155
MRPL16 mitochondrial ribosomal protein L16 -3.20127
SIX1 SIX homeobox 1 -3.19693
VENTXP1 VENT homeobox pseudogene 1 -3.19639
ZBTB3 zinc finger and BTB domain containing 3 -3.19255
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -3.19024
HIGD2A HIG1 hypoxia inducible domain family, member 2A -3.18989
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) -3.18817
UNKL unkempt family zinc finger-like -3.18609
PEX5L peroxisomal biogenesis factor 5-like -3.17937
GRIK1 glutamate receptor, ionotropic, kainate 1 -3.17786
MFAP5 microfibrillar associated protein 5 -3.17763
BTF3 basic transcription factor 3 -3.17749
FRK fyn-related Src family tyrosine kinase -3.16377
ZBTB33 zinc finger and BTB domain containing 33 -3.15974
DLG2 discs, large homolog 2 (Drosophila) -3.15856
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -3.15611
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) -3.15272
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 -3.14182
HSF4 heat shock transcription factor 4 -3.14174
PAGE4 P antigen family, member 4 (prostate associated) -3.14014
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) -3.13901
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 -3.13898
WBP4 WW domain binding protein 4 -3.13678
PTH parathyroid hormone -3.13291
MYO7B myosin VIIB -3.13282
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta -3.13243
MBNL3 muscleblind-like splicing regulator 3 -3.13128
FSHB follicle stimulating hormone, beta polypeptide -3.12804
CEP43 centrosomal protein 43 -3.12671
CD207 CD207 molecule, langerin -3.12663
NPTN neuroplastin -3.12563
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -3.12246
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -3.12204
FNDC11 fibronectin type III domain containing 11 -3.11925
RRH retinal pigment epithelium-derived rhodopsin homolog -3.11584
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -3.11569
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -3.1152
MAGIX MAGI family member, X-linked -3.11479
TBXT T-box transcription factor T -3.114
MAP3K7CL MAP3K7 C-terminal like -3.11319
ATP5MG ATP synthase membrane subunit g -3.11287
EPB41L5 erythrocyte membrane protein band 4.1 like 5 -3.10861
SPO11 SPO11 meiotic protein covalently bound to DSB -3.10347
MSX2 msh homeobox 2 -3.10111
PRPF19 pre-mRNA processing factor 19 -3.1
GFRA1 GDNF family receptor alpha 1 -3.09934
TMX2 thioredoxin-related transmembrane protein 2 -3.09814
OSGIN2 oxidative stress induced growth inhibitor family member 2 -3.09605
FAM169A family with sequence similarity 169, member A -3.09441
ACSS3 acyl-CoA synthetase short-chain family member 3 -3.09284
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) -3.09227
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 -3.08688
LIPC lipase, hepatic -3.08641
FOXN2 forkhead box N2 -3.08569
IL37 interleukin 37 -3.08417
GP6 glycoprotein VI (platelet) -3.07822
MTRF1 mitochondrial translational release factor 1 -3.07691
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -3.07578
ANKRD6 ankyrin repeat domain 6 -3.07537
AVL9 AVL9 homolog (S. cerevisiase) -3.06695
FGL2 fibrinogen-like 2 -3.06504
COX6C cytochrome c oxidase subunit VIc -3.06089
SYCE1L synaptonemal complex central element protein 1-like -3.05632
YBX3 Y box binding protein 3 -3.05203
DUT deoxyuridine triphosphatase -3.04618
BTBD7 BTB (POZ) domain containing 7 -3.03889
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa -3.03266
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -3.03219
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -3.031
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae) -3.03006
MYH15 myosin, heavy chain 15 -3.02901
HSPA4L heat shock 70kDa protein 4-like -3.0286
PCYT1A phosphate cytidylyltransferase 1, choline, alpha -3.02616
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase -3.02547
AGGF1 angiogenic factor with G patch and FHA domains 1 -3.02462
SCN11A sodium channel, voltage gated, type XI alpha subunit -3.01894
CKS2 CDC28 protein kinase regulatory subunit 2 -3.01684
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -3.01617
CORO1B coronin, actin binding protein, 1B -3.01527
FBXL4 F-box and leucine-rich repeat protein 4 -3.01513
TAS2R10 taste receptor, type 2, member 10 -3.01464
ADORA2B adenosine A2b receptor -3.01391
RHBG Rh family, B glycoprotein (gene/pseudogene) -3.01317
CEP164 centrosomal protein 164kDa -3.01131
VAMP5 vesicle-associated membrane protein 5 -3.01049
ATP4B ATPase, H+/K+ exchanging, beta polypeptide -3.00981
GDF11 growth differentiation factor 11 -3.00955
RAPSN receptor-associated protein of the synapse -3.00274
LIMA1 LIM domain and actin binding 1 -3.0001