praziquantel-3189 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the praziquantel-3189 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM28 ADAM metallopeptidase domain 28
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ALK anaplastic lymphoma receptor tyrosine kinase
ANK2 ankyrin 2, neuronal
ARHGAP44 Rho GTPase activating protein 44
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASCL1 achaete-scute family bHLH transcription factor 1
BNC2 basonuclin 2
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC57 coiled-coil domain containing 57
CCDC9 coiled-coil domain containing 9
CD6 CD6 molecule
CD72 CD72 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHAT choline O-acetyltransferase
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLEC4A C-type lectin domain family 4, member A
CLEC7A C-type lectin domain family 7, member A
CTSZ cathepsin Z
DGCR8 DGCR8 microprocessor complex subunit
EHD1 EH-domain containing 1
FAM131B family with sequence similarity 131, member B
FBXO41 F-box protein 41
FKBP10 FK506 binding protein 10, 65 kDa
FN1 fibronectin 1
GIF gastric intrinsic factor (vitamin B synthesis)
GJD2 gap junction protein, delta 2, 36kDa
GLP1R glucagon-like peptide 1 receptor
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPC5 glypican 5
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
GSTTP1 glutathione S-transferase theta pseudogene 1
GYPB glycophorin B (MNS blood group)
HAP1 huntingtin-associated protein 1
HDAC7 histone deacetylase 7
HIST1H1T histone cluster 1, H1t
HIST1H3E histone cluster 1, H3e
ICAM1 intercellular adhesion molecule 1
IGKV1D-13 immunoglobulin kappa variable 1D-13
IL12RB2 interleukin 12 receptor, beta 2
ING4 inhibitor of growth family, member 4
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KLHL35 kelch-like family member 35
KPNA5 karyopherin alpha 5 (importin alpha 6)
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARK1 MAP/microtubule affinity-regulating kinase 1
MCAM melanoma cell adhesion molecule
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MLXIP MLX interacting protein
MPPE1 metallophosphoesterase 1
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYO7A myosin VIIA
MYO9B myosin IXB
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NOL10 nucleolar protein 10
NOVA2 neuro-oncological ventral antigen 2
OPLAH 5-oxoprolinase (ATP-hydrolysing)
PADI3 peptidyl arginine deiminase, type III
PCDH11X protocadherin 11 X-linked
PCDH17 protocadherin 17
PDCD6 programmed cell death 6
PDLIM4 PDZ and LIM domain 4
PER1 period circadian clock 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PSD4 pleckstrin and Sec7 domain containing 4
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
RGS12 regulator of G-protein signaling 12
RPL10 ribosomal protein L10
RRBP1 ribosome binding protein 1
RUNX1 runt-related transcription factor 1
RYR2 ryanodine receptor 2 (cardiac)
S100A2 S100 calcium binding protein A2
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SETD1A SET domain containing 1A
SH3BP2 SH3-domain binding protein 2
SIK3 SIK family kinase 3
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SPDEF SAM pointed domain containing ETS transcription factor
TBX6 T-box 6
TDRKH tudor and KH domain containing
THAP3 THAP domain containing, apoptosis associated protein 3
TLE4 transducin-like enhancer of split 4
TNK2 tyrosine kinase, non-receptor, 2
TRAK1 trafficking protein, kinesin binding 1
TRAV8-3 T cell receptor alpha variable 8-3
TRIM46 tripartite motif containing 46
TUBA4B tubulin, alpha 4b
ZNF112 zinc finger protein 112
ZNF154 zinc finger protein 154
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACBD4 acyl-CoA binding domain containing 4
ACSF2 acyl-CoA synthetase family member 2
ACTG2 actin, gamma 2, smooth muscle, enteric
ADM adrenomedullin
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
AXIN1 axin 1
BMP4 bone morphogenetic protein 4
C17ORF80 chromosome 17 open reading frame 80
C22ORF46 chromosome 22 open reading frame 46
C2ORF44 chromosome 2 open reading frame 44
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMKV CaM kinase-like vesicle-associated
CARD8 caspase recruitment domain family, member 8
CBX8 chromobox homolog 8
CDK3 cyclin-dependent kinase 3
CLCN6 chloride channel, voltage-sensitive 6
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DSCAM Down syndrome cell adhesion molecule
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DYSF dysferlin
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EXOC6B exocyst complex component 6B
FCHO1 FCH domain only 1
FGF4 fibroblast growth factor 4
FGGY FGGY carbohydrate kinase domain containing
FOXN2 forkhead box N2
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPX1 glutathione peroxidase 1
GRAMD4 GRAM domain containing 4
GRB7 growth factor receptor-bound protein 7
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IDI2-AS1 IDI2 antisense RNA 1
IFT140 intraflagellar transport 140
IL15RA interleukin 15 receptor, alpha
IL4R interleukin 4 receptor
ITGA10 integrin, alpha 10
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITPKB inositol-trisphosphate 3-kinase B
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF13A kinesin family member 13A
KRT83 keratin 83, type II
LDHB lactate dehydrogenase B
LPCAT3 lysophosphatidylcholine acyltransferase 3
LRRC20 leucine rich repeat containing 20
LYZ lysozyme
LZTFL1 leucine zipper transcription factor-like 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MPO myeloperoxidase
MSI1 musashi RNA-binding protein 1
MUC3A mucin 3A, cell surface associated
MYL5 myosin, light chain 5, regulatory
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NIPAL2 NIPA-like domain containing 2
NNAT neuronatin
NPIPB3 nuclear pore complex interacting protein family, member B3
NRSN2 neurensin 2
NXPH4 neurexophilin 4
PACS1 phosphofurin acidic cluster sorting protein 1
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLL polymerase (DNA directed), lambda
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PTK6 protein tyrosine kinase 6
RAD54L2 RAD54-like 2 (S. cerevisiae)
RCAN3 RCAN family member 3
RCOR3 REST corepressor 3
RELN reelin
RNF121 ring finger protein 121
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
RNF39 ring finger protein 39
RPH3AL rabphilin 3A-like (without C2 domains)
RPL10L ribosomal protein L10-like
SCAMP5 secretory carrier membrane protein 5
SIRT6 sirtuin 6
SLC22A14 solute carrier family 22, member 14
SLC44A1 solute carrier family 44 (choline transporter), member 1
SND1-IT1 SND1 intronic transcript 1
SUN2 Sad1 and UNC84 domain containing 2
TAOK1 TAO kinase 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TRAIP TRAF interacting protein
TWSG1 twisted gastrulation BMP signaling modulator 1
UBXN6 UBX domain protein 6
VEGFB vascular endothelial growth factor B
WDR25 WD repeat domain 25
WNT10B wingless-type MMTV integration site family, member 10B
ZC3H3 zinc finger CCCH-type containing 3
ZNF324 zinc finger protein 324
ZNF329 zinc finger protein 329
ZNF35 zinc finger protein 35
ZNF365 zinc finger protein 365