| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the praziquantel-5874 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ACTR5 | ARP5 actin-related protein 5 homolog (yeast) |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ARHGAP22 | Rho GTPase activating protein 22 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARMC4 | armadillo repeat containing 4 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CD6 | CD6 molecule |
| CHI3L2 | chitinase 3-like 2 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLEC16A | C-type lectin domain family 16, member A |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| COL11A2 | collagen, type XI, alpha 2 |
| COL5A1 | collagen, type V, alpha 1 |
| CPNE7 | copine VII |
| CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
| DENND2D | DENN/MADD domain containing 2D |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EFNB1 | ephrin-B1 |
| EHD1 | EH-domain containing 1 |
| ELAC2 | elaC ribonuclease Z 2 |
| EPAS1 | endothelial PAS domain protein 1 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FGF12 | fibroblast growth factor 12 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| IKBKAP | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| INO80B | INO80 complex subunit B |
| INS | insulin |
| IPO8 | importin 8 |
| IRGQ | immunity-related GTPase family, Q |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KRT34 | keratin 34, type I |
| KRTAP9-9 | keratin associated protein 9-9 |
| KYNU | kynureninase |
| LAMB4 | laminin, beta 4 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LOC729164 | hCG1732469 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MAP2K2 | mitogen-activated protein kinase kinase 2 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MMP10 | matrix metallopeptidase 10 |
| MST1 | macrophage stimulating 1 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NEK11 | NIMA-related kinase 11 |
| NOX1 | NADPH oxidase 1 |
| OSBPL10 | oxysterol binding protein-like 10 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PER1 | period circadian clock 1 |
| PLCH1 | phospholipase C, eta 1 |
| PLP1 | proteolipid protein 1 |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| POLL | polymerase (DNA directed), lambda |
| RAD54B | RAD54 homolog B (S. cerevisiae) |
| RANBP1 | RAN binding protein 1 |
| SIX3 | SIX homeobox 3 |
| SLC18A3 | solute carrier family 18 (vesicular acetylcholine transporter), member 3 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SQSTM1 | sequestosome 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TEAD3 | TEA domain family member 3 |
| TLE2 | transducin-like enhancer of split 2 |
| TLE6 | transducin-like enhancer of split 6 |
| TMEM19 | transmembrane protein 19 |
| TOP3A | topoisomerase (DNA) III alpha |
| TPP1 | tripeptidyl peptidase I |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| UBXN1 | UBX domain protein 1 |
| USB1 | U6 snRNA biogenesis 1 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF318 | zinc finger protein 318 |
| ZNF606 | zinc finger protein 606 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| AAR2 | AAR2 splicing factor homolog (S. cerevisiae) |
| ACTR1B | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) |
| AFAP1 | actin filament associated protein 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| ARL14 | ADP-ribosylation factor-like 14 |
| ASB8 | ankyrin repeat and SOCS box containing 8 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BCAS4 | breast carcinoma amplified sequence 4 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| BRWD1 | bromodomain and WD repeat domain containing 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C11ORF73 | chromosome 11 open reading frame 73 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CAPN15 | calpain 15 |
| CCDC94 | coiled-coil domain containing 94 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CENPT | centromere protein T |
| CFAP69 | cilia and flagella associated protein 69 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYB5R4 | cytochrome b5 reductase 4 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| ECM1 | extracellular matrix protein 1 |
| EGF | epidermal growth factor |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| GBX2 | gastrulation brain homeobox 2 |
| GLCE | glucuronic acid epimerase |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3G | histone cluster 1, H3g |
| HMG20A | high mobility group 20A |
| HOXC10 | homeobox C10 |
| IFNA14 | interferon, alpha 14 |
| KIAA0894 | KIAA0894 protein |
| KIAA0895 | KIAA0895 |
| KIF13B | kinesin family member 13B |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAGEF1 | melanoma antigen family F1 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MFSD10 | major facilitator superfamily domain containing 10 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MITF | microphthalmia-associated transcription factor |
| MYLK | myosin light chain kinase |
| NDP | Norrie disease (pseudoglioma) |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OTUD3 | OTU deubiquitinase 3 |
| P3H1 | prolyl 3-hydroxylase 1 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCBP4 | poly(rC) binding protein 4 |
| PEX13 | peroxisomal biogenesis factor 13 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLIN3 | perilipin 3 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| RAI2 | retinoic acid induced 2 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPL10L | ribosomal protein L10-like |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| TEX40 | testis expressed 40 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TLN1 | talin 1 |
| TMEM2 | transmembrane protein 2 |
| TMEM209 | transmembrane protein 209 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSPYL2 | TSPY-like 2 |
| TTC26 | tetratricopeptide repeat domain 26 |
| TUBA3D | tubulin, alpha 3d |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBXN6 | UBX domain protein 6 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| WDR37 | WD repeat domain 37 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF254 | zinc finger protein 254 |
| ZNF324 | zinc finger protein 324 |
| ZNF804A | zinc finger protein 804A |
| ZNF862 | zinc finger protein 862 |