| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the praziquantel-7228 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AK1 | adenylate kinase 1 |
| AK2 | adenylate kinase 2 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ATM | ATM serine/threonine kinase |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BAIAP3 | BAI1-associated protein 3 |
| BCL2 | B-cell CLL/lymphoma 2 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CD300A | CD300a molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD82 | CD82 molecule |
| CD8A | CD8a molecule |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CLCA2 | chloride channel accessory 2 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CPD | carboxypeptidase D |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CTBS | chitobiase, di-N-acetyl- |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DPYS | dihydropyrimidinase |
| DRD2 | dopamine receptor D2 |
| ELL | elongation factor RNA polymerase II |
| FDPS | farnesyl diphosphate synthase |
| FGB | fibrinogen beta chain |
| FLT4 | fms-related tyrosine kinase 4 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GALR3 | galanin receptor 3 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GPR63 | G protein-coupled receptor 63 |
| GPR85 | G protein-coupled receptor 85 |
| GSAP | gamma-secretase activating protein |
| HHEX | hematopoietically expressed homeobox |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HR | hair growth associated |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IRF8 | interferon regulatory factor 8 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| KHSRP | KH-type splicing regulatory protein |
| KIAA0319L | KIAA0319-like |
| KIF1C | kinesin family member 1C |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KLF12 | Kruppel-like factor 12 |
| KLHL22 | kelch-like family member 22 |
| LIN7A | lin-7 homolog A (C. elegans) |
| MIIP | migration and invasion inhibitory protein |
| MIR622 | microRNA 622 |
| MTA1 | metastasis associated 1 |
| MTSS1 | metastasis suppressor 1 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NIPAL2 | NIPA-like domain containing 2 |
| PARD6B | par-6 family cell polarity regulator beta |
| PARVA | parvin, alpha |
| PCM1 | pericentriolar material 1 |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PML | promyelocytic leukemia |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PTCRA | pre T-cell antigen receptor alpha |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RIF1 | replication timing regulatory factor 1 |
| RIN3 | Ras and Rab interactor 3 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| SETD1A | SET domain containing 1A |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SLC13A4 | solute carrier family 13 (sodium/sulfate symporter), member 4 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SNX13 | sorting nexin 13 |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SRI | sorcin |
| SSPN | sarcospan |
| ST7 | suppression of tumorigenicity 7 |
| STK3 | serine/threonine kinase 3 |
| STOML1 | stomatin (EPB72)-like 1 |
| SVIL | supervillin |
| SYT5 | synaptotagmin V |
| TAT | tyrosine aminotransferase |
| TBC1D17 | TBC1 domain family, member 17 |
| TMEM63A | transmembrane protein 63A |
| TSPAN9 | tetraspanin 9 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TUBA3C | tubulin, alpha 3c |
| VN1R1 | vomeronasal 1 receptor 1 |
| VPRBP | Vpr (HIV-1) binding protein |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| Symbol | Name |
|---|---|
| ACTN4 | actinin, alpha 4 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ALPK1 | alpha-kinase 1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ARMC6 | armadillo repeat containing 6 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATG2A | autophagy related 2A |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BCORL1 | BCL6 corepressor-like 1 |
| BEX4 | brain expressed, X-linked 4 |
| C12ORF43 | chromosome 12 open reading frame 43 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CBR4 | carbonyl reductase 4 |
| CCDC25 | coiled-coil domain containing 25 |
| CCNT1 | cyclin T1 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CEP131 | centrosomal protein 131kDa |
| CHKB | choline kinase beta |
| CHMP6 | charged multivesicular body protein 6 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DUSP2 | dual specificity phosphatase 2 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| ERCC5 | excision repair cross-complementation group 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAAH | fatty acid amide hydrolase |
| FAM169A | family with sequence similarity 169, member A |
| FBXO2 | F-box protein 2 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GPR87 | G protein-coupled receptor 87 |
| GSTT1 | glutathione S-transferase theta 1 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HDAC3 | histone deacetylase 3 |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HIST1H2BO | histone cluster 1, H2bo |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IRX4 | iroquois homeobox 4 |
| KLC2 | kinesin light chain 2 |
| LRRC61 | leucine rich repeat containing 61 |
| MED15 | mediator complex subunit 15 |
| MEIS1 | Meis homeobox 1 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| NBEAL2 | neurobeachin-like 2 |
| NLK | nemo-like kinase |
| NRSN2 | neurensin 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PLD3 | phospholipase D family, member 3 |
| POLH | polymerase (DNA directed), eta |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| REST | RE1-silencing transcription factor |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SIRT6 | sirtuin 6 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SNX15 | sorting nexin 15 |
| SSFA2 | sperm specific antigen 2 |
| STX1A | syntaxin 1A (brain) |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TDRD1 | tudor domain containing 1 |
| TEAD3 | TEA domain family member 3 |
| THBS3 | thrombospondin 3 |
| TMC5 | transmembrane channel-like 5 |
| TRABD | TraB domain containing |
| UBXN6 | UBX domain protein 6 |
| USB1 | U6 snRNA biogenesis 1 |
| VASH1 | vasohibin 1 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) |
| VWA1 | von Willebrand factor A domain containing 1 |
| YBX2 | Y box binding protein 2 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF141 | zinc finger protein 141 |
| ZNF492 | zinc finger protein 492 |
| ZNF573 | zinc finger protein 573 |
| ZNF668 | zinc finger protein 668 |
| ZNF669 | zinc finger protein 669 |
| ZNF672 | zinc finger protein 672 |
