| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the prazosin-3098 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| ADRA2C | adrenoceptor alpha 2C |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ALOX5 | arachidonate 5-lipoxygenase |
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ATP10A | ATPase, class V, type 10A |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BGN | biglycan |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD59 | CD59 molecule, complement regulatory protein |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CLDN17 | claudin 17 |
| CNTN1 | contactin 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COMT | catechol-O-methyltransferase |
| COPE | coatomer protein complex, subunit epsilon |
| CREBBP | CREB binding protein |
| CREM | cAMP responsive element modulator |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DPEP2 | dipeptidase 2 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EML2 | echinoderm microtubule associated protein like 2 |
| EN1 | engrailed homeobox 1 |
| EPS8L1 | EPS8-like 1 |
| FLJ11292 | |
| GALNT8 | polypeptide N-acetylgalactosaminyltransferase 8 |
| GPC4 | glypican 4 |
| GPM6B | glycoprotein M6B |
| GPX3 | glutathione peroxidase 3 |
| H2AFJ | H2A histone family, member J |
| HAB1 | B1 for mucin |
| HNMT | histamine N-methyltransferase |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| ING2 | inhibitor of growth family, member 2 |
| ITGB1BP2 | integrin beta 1 binding protein (melusin) 2 |
| ITGB4 | integrin, beta 4 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KLK3 | kallikrein-related peptidase 3 |
| KRT86 | keratin 86, type II |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LINC00472 | long intergenic non-protein coding RNA 472 |
| LMTK1 | lemur tail kinase 1 |
| LOC257152 | uncharacterized LOC257152 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LRRC20 | leucine rich repeat containing 20 |
| LRRN2 | leucine rich repeat neuronal 2 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAGEA5 | melanoma antigen family A5 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MRPL20 | mitochondrial ribosomal protein L20 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MYH14 | myosin, heavy chain 14, non-muscle |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NUDT7 | nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PLSCR3 | phospholipid scramblase 3 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| PRAMEF11 | PRAME family member 11 |
| PSD | pleckstrin and Sec7 domain containing |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PURG | purine-rich element binding protein G |
| RAB33A | RAB33A, member RAS oncogene family |
| RAB6B | RAB6B, member RAS oncogene family |
| RARG | retinoic acid receptor, gamma |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RPL35A | ribosomal protein L35a |
| SDC1 | syndecan 1 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOX10 | SRY (sex determining region Y)-box 10 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| SV2C | synaptic vesicle glycoprotein 2C |
| THBS1 | thrombospondin 1 |
| TMEM2 | transmembrane protein 2 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| WDR78 | WD repeat domain 78 |
| YLPM1 | YLP motif containing 1 |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF646 | zinc finger protein 646 |
| ZNF839 | zinc finger protein 839 |
| Symbol | Name |
|---|---|
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACD | adrenocortical dysplasia homolog (mouse) |
| AEN | apoptosis enhancing nuclease |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CIDEC | cell death-inducing DFFA-like effector c |
| CRYL1 | crystallin, lambda 1 |
| CTSO | cathepsin O |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DEPDC1 | DEP domain containing 1 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNM3 | dynamin 3 |
| DPF2 | D4, zinc and double PHD fingers family 2 |
| FER | fer (fps/fes related) tyrosine kinase |
| FGL1 | fibrinogen-like 1 |
| FKBP5 | FK506 binding protein 5 |
| FZD2 | frizzled class receptor 2 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GPR63 | G protein-coupled receptor 63 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HDAC5 | histone deacetylase 5 |
| HMCES | 5-hydroxymethylcytosine (hmC) binding, ES cell-specific |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGLV1-44 | immunoglobulin lambda variable 1-44 |
| IL11RA | interleukin 11 receptor, alpha |
| IQCG | IQ motif containing G |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA0319L | KIAA0319-like |
| KIF1B | kinesin family member 1B |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOC157562 | uncharacterized LOC157562 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LTC4S | leukotriene C4 synthase |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MAGEF1 | melanoma antigen family F1 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MB | myoglobin |
| MCRS1 | microspherule protein 1 |
| METTL8 | methyltransferase like 8 |
| MICA | MHC class I polypeptide-related sequence A |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MON1B | MON1 secretory trafficking family member B |
| MXD3 | MAX dimerization protein 3 |
| NAG18 | NAG18 mRNA |
| NDE1 | nudE neurodevelopment protein 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLTP | phospholipid transfer protein |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PSKH1 | protein serine kinase H1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SNX15 | sorting nexin 15 |
| SP140 | SP140 nuclear body protein |
| SPATA1 | spermatogenesis associated 1 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| ST7L | suppression of tumorigenicity 7 like |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STK16 | serine/threonine kinase 16 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TAS2R10 | taste receptor, type 2, member 10 |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| THEM6 | thioesterase superfamily member 6 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMC5 | transmembrane channel-like 5 |
| TMEM206 | transmembrane protein 206 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| ULBP2 | UL16 binding protein 2 |
| USB1 | U6 snRNA biogenesis 1 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR76 | WD repeat domain 76 |
| XYLT2 | xylosyltransferase II |
| ZNF345 | zinc finger protein 345 |
| ZNF350 | zinc finger protein 350 |
| ZNF573 | zinc finger protein 573 |
| ZNF862 | zinc finger protein 862 |
