| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the prazosin-5416 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCK2 | aarF domain containing kinase 2 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AHI1 | Abelson helper integration site 1 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ALS2CL | ALS2 C-terminal like |
| APAF1 | apoptotic peptidase activating factor 1 |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ASMT | acetylserotonin O-methyltransferase |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
| BEST2 | bestrophin 2 |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CCNO | cyclin O |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CDON | cell adhesion associated, oncogene regulated |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLEC4A | C-type lectin domain family 4, member A |
| CNTN5 | contactin 5 |
| COL11A2 | collagen, type XI, alpha 2 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CRTAM | cytotoxic and regulatory T cell molecule |
| CYTH1 | cytohesin 1 |
| DFNB31 | deafness, autosomal recessive 31 |
| DOCK6 | dedicator of cytokinesis 6 |
| DPYSL4 | dihydropyrimidinase-like 4 |
| DYM | dymeclin |
| EFNB3 | ephrin-B3 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| FHIT | fragile histidine triad |
| FLT1 | fms-related tyrosine kinase 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| GLP1R | glucagon-like peptide 1 receptor |
| GLS | glutaminase |
| GNAS | GNAS complex locus |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GP6 | glycoprotein VI (platelet) |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GSAP | gamma-secretase activating protein |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL2RB | interleukin 2 receptor, beta |
| KIF1C | kinesin family member 1C |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LEPR | leptin receptor |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MPO | myeloperoxidase |
| MST1 | macrophage stimulating 1 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle |
| NDRG2 | NDRG family member 2 |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NMT1 | N-myristoyltransferase 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| OGDHL | oxoglutarate dehydrogenase-like |
| OR7E24 | olfactory receptor, family 7, subfamily E, member 24 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PIAS2 | protein inhibitor of activated STAT, 2 |
| PIGR | polymeric immunoglobulin receptor |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLAU | plasminogen activator, urokinase |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCD1 | phospholipase C, delta 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| RB1 | retinoblastoma 1 |
| RBM26 | RNA binding motif protein 26 |
| REEP2 | receptor accessory protein 2 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SMAD3 | SMAD family member 3 |
| SPPL2B | signal peptide peptidase like 2B |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TBXA2R | thromboxane A2 receptor |
| THBS1 | thrombospondin 1 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TLR2 | toll-like receptor 2 |
| TMC6 | transmembrane channel-like 6 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TPMT | thiopurine S-methyltransferase |
| TRIM31 | tripartite motif containing 31 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| UPK2 | uroplakin 2 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| WNK1 | WNK lysine deficient protein kinase 1 |
| WTAP | Wilms tumor 1 associated protein |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACSF2 | acyl-CoA synthetase family member 2 |
| AEBP1 | AE binding protein 1 |
| AES | amino-terminal enhancer of split |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ALPK1 | alpha-kinase 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CA11 | carbonic anhydrase XI |
| CD8A | CD8a molecule |
| CEP72 | centrosomal protein 72kDa |
| CHKB | choline kinase beta |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN15 | claudin 15 |
| COPS7B | COP9 signalosome subunit 7B |
| CORT | cortistatin |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRY2 | cryptochrome circadian clock 2 |
| CTSK | cathepsin K |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| ETV6 | ets variant 6 |
| FAM120C | family with sequence similarity 120C |
| FANCC | Fanconi anemia, complementation group C |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GPATCH3 | G patch domain containing 3 |
| GPR87 | G protein-coupled receptor 87 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H2AL | histone cluster 1, H2al |
| HIST1H4E | histone cluster 1, H4e |
| HOXC5 | homeobox C5 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT54 | intraflagellar transport 54 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| JUNB | jun B proto-oncogene |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KIAA0894 | KIAA0894 protein |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KRT15 | keratin 15, type I |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MRPS18C | mitochondrial ribosomal protein S18C |
| NAIP | NLR family, apoptosis inhibitory protein |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NEK11 | NIMA-related kinase 11 |
| NES | nestin |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NKX3-2 | NK3 homeobox 2 |
| NPTX1 | neuronal pentraxin I |
| ONECUT2 | one cut homeobox 2 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF39 | ring finger protein 39 |
| ROM1 | retinal outer segment membrane protein 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| S100A9 | S100 calcium binding protein A9 |
| SCAI | suppressor of cancer cell invasion |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SMIM14 | small integral membrane protein 14 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STX1A | syntaxin 1A (brain) |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCHH | trichohyalin |
| TLN1 | talin 1 |
| TMEM120B | transmembrane protein 120B |
| TMEM121 | transmembrane protein 121 |
| TMEM57 | transmembrane protein 57 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TUBA3C | tubulin, alpha 3c |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USP20 | ubiquitin specific peptidase 20 |
| VASH1 | vasohibin 1 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR62 | WD repeat domain 62 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF74 | zinc finger protein 74 |
