prazosin-6475 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the prazosin-6475 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ADCY6 adenylate cyclase 6
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALDOB aldolase B, fructose-bisphosphate
ANKFY1 ankyrin repeat and FYVE domain containing 1
AQP1 aquaporin 1 (Colton blood group)
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
C19ORF66 chromosome 19 open reading frame 66
CDK13 cyclin-dependent kinase 13
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
COL14A1 collagen, type XIV, alpha 1
COMT catechol-O-methyltransferase
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CTIF CBP80/20-dependent translation initiation factor
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DIO2 deiodinase, iodothyronine, type II
DLC1 DLC1 Rho GTPase activating protein
EDA ectodysplasin A
EDN3 endothelin 3
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FBN1 fibrillin 1
FBXO4 F-box protein 4
FGF1 fibroblast growth factor 1 (acidic)
FKBP10 FK506 binding protein 10, 65 kDa
FRMD4B FERM domain containing 4B
FXYD5 FXYD domain containing ion transport regulator 5
GAS6 growth arrest-specific 6
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GJB3 gap junction protein, beta 3, 31kDa
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
GRIP2 glutamate receptor interacting protein 2
GRK5 G protein-coupled receptor kinase 5
HCLS1 hematopoietic cell-specific Lyn substrate 1
HFE hemochromatosis
HLA-A major histocompatibility complex, class I, A
HYAL1 hyaluronoglucosaminidase 1
IAPP islet amyloid polypeptide
IRS4 insulin receptor substrate 4
JADE2 jade family PHD finger 2
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KIF1C kinesin family member 1C
KIF21B kinesin family member 21B
KIF25-AS1 KIF25 antisense RNA 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LBX1 ladybird homeobox 1
LINC00472 long intergenic non-protein coding RNA 472
LPAR3 lysophosphatidic acid receptor 3
MCAM melanoma cell adhesion molecule
MEFV Mediterranean fever
MKRN3 makorin ring finger protein 3
MST1 macrophage stimulating 1
NEFM neurofilament, medium polypeptide
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NRF1 nuclear respiratory factor 1
NXF2 nuclear RNA export factor 2
PARVA parvin, alpha
PCDH7 protocadherin 7
PCDHB3 protocadherin beta 3
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDZD2 PDZ domain containing 2
PHF3 PHD finger protein 3
PITX1 paired-like homeodomain 1
PLXNB1 plexin B1
PRKD1 protein kinase D1
PTGFR prostaglandin F receptor (FP)
PVR poliovirus receptor
RAB35 RAB35, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASAL2 RAS protein activator like 2
RFPL3 ret finger protein-like 3
RTN2 reticulon 2
RUNX1 runt-related transcription factor 1
SAYSD1 SAYSVFN motif domain containing 1
SCRG1 stimulator of chondrogenesis 1
SERGEF secretion regulating guanine nucleotide exchange factor
SIRT5 sirtuin 5
SLC6A16 solute carrier family 6, member 16
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPICE1 spindle and centriole associated protein 1
SPON1 spondin 1, extracellular matrix protein
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SUGP1 SURP and G patch domain containing 1
TG thyroglobulin
THPO thrombopoietin
TIAM2 T-cell lymphoma invasion and metastasis 2
TLR4 toll-like receptor 4
TRABD TraB domain containing
TSC22D2 TSC22 domain family, member 2
TTC38 tetratricopeptide repeat domain 38
TUBGCP3 tubulin, gamma complex associated protein 3
TWIST1 twist family bHLH transcription factor 1
ULBP1 UL16 binding protein 1
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
YY2 YY2 transcription factor
ZNF318 zinc finger protein 318
ZNF384 zinc finger protein 384

decreased expression

Symbol Name
ARHGAP11A Rho GTPase activating protein 11A
ASPN asporin
ATAD5 ATPase family, AAA domain containing 5
BFSP1 beaded filament structural protein 1, filensin
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C10ORF95 chromosome 10 open reading frame 95
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMTA1 calmodulin binding transcription activator 1
CCNO cyclin O
CHRM3 cholinergic receptor, muscarinic 3
CLCN6 chloride channel, voltage-sensitive 6
CLDN17 claudin 17
CLDND1 claudin domain containing 1
CLSPN claspin
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CST6 cystatin E/M
CTNNBL1 catenin, beta like 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCLRE1A DNA cross-link repair 1A
EXOC5 exocyst complex component 5
FAM189A2 family with sequence similarity 189, member A2
FUZ fuzzy planar cell polarity protein
GPATCH3 G patch domain containing 3
HIST1H2BI histone cluster 1, H2bi
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC5 homeobox C5
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
ICK intestinal cell (MAK-like) kinase
INO80D INO80 complex subunit D
IPO8 importin 8
JMJD4 jumonji domain containing 4
JRKL JRK-like
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIAA1456 KIAA1456
KLHL28 kelch-like family member 28
KLHL36 kelch-like family member 36
LARP6 La ribonucleoprotein domain family, member 6
LINC00597 long intergenic non-protein coding RNA 597
LOC100131532 uncharacterized LOC100131532
LOC257152 uncharacterized LOC257152
LOC390998 ribosomal protein L10 pseudogene
LZTFL1 leucine zipper transcription factor-like 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MATK megakaryocyte-associated tyrosine kinase
MCTP1 multiple C2 domains, transmembrane 1
MED31 mediator complex subunit 31
MXD3 MAX dimerization protein 3
MYO1F myosin IF
NCALD neurocalcin delta
NELL2 NEL-like 2 (chicken)
NLGN1 neuroligin 1
NOL12 nucleolar protein 12
NPIPB15 nuclear pore complex interacting protein family, member B15
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PADI1 peptidyl arginine deiminase, type I
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PRSS50 protease, serine, 50
PTPRE protein tyrosine phosphatase, receptor type, E
PTPRU protein tyrosine phosphatase, receptor type, U
QTRT1 queuine tRNA-ribosyltransferase 1
RAPSN receptor-associated protein of the synapse
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF25 ring finger protein 25
RPAP2 RNA polymerase II associated protein 2
RPGRIP1L RPGRIP1-like
RPL23AP32 ribosomal protein L23a pseudogene 32
SFRP5 secreted frizzled-related protein 5
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC41A3 solute carrier family 41, member 3
SNHG3 small nucleolar RNA host gene 3
SPINK4 serine peptidase inhibitor, Kazal type 4
SRD5A3 steroid 5 alpha-reductase 3
SREK1IP1 SREK1-interacting protein 1
SYCP2 synaptonemal complex protein 2
TARP TCR gamma alternate reading frame protein
TBC1D2 TBC1 domain family, member 2
TCTN1 tectonic family member 1
TESC tescalcin
TIGD6 tigger transposable element derived 6
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM212 transmembrane protein 212
TMEM254 transmembrane protein 254
TRPM4 transient receptor potential cation channel, subfamily M, member 4
VASH1 vasohibin 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR25 WD repeat domain 25
WLS wntless Wnt ligand secretion mediator
ZFAND3 zinc finger, AN1-type domain 3
ZNF37BP zinc finger protein 37B, pseudogene
ZNF506 zinc finger protein 506
ZNF665 zinc finger protein 665
ZSWIM1 zinc finger, SWIM-type containing 1