| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the prazosin-826 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| AASS | aminoadipate-semialdehyde synthase |
| ABO | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) |
| ADAM2 | ADAM metallopeptidase domain 2 |
| ADAM8 | ADAM metallopeptidase domain 8 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ALB | albumin |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ASPH | aspartate beta-hydroxylase |
| ATXN3 | ataxin 3 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CLDN1 | claudin 1 |
| CLDN17 | claudin 17 |
| COL1A1 | collagen, type I, alpha 1 |
| COMP | cartilage oligomeric matrix protein |
| CORO7 | coronin 7 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 |
| DACH1 | dachshund family transcription factor 1 |
| DAPK2 | death-associated protein kinase 2 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DSC3 | desmocollin 3 |
| EPHB2 | EPH receptor B2 |
| FAM212B | family with sequence similarity 212, member B |
| FAM49B | family with sequence similarity 49, member B |
| FLJ11292 | |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GK | glycerol kinase |
| GLIPR1 | GLI pathogenesis-related 1 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| GRM4 | glutamate receptor, metabotropic 4 |
| GRM8 | glutamate receptor, metabotropic 8 |
| HES2 | hes family bHLH transcription factor 2 |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3B | histone cluster 1, H3b |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IDS | iduronate 2-sulfatase |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IL36RN | interleukin 36 receptor antagonist |
| INSIG1 | insulin induced gene 1 |
| IRF6 | interferon regulatory factor 6 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KRT20 | keratin 20, type I |
| LAMA4 | laminin, alpha 4 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LHX1 | LIM homeobox 1 |
| LPIN1 | lipin 1 |
| MAOA | monoamine oxidase A |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MIR622 | microRNA 622 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYT1L | myelin transcription factor 1-like |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NF2 | neurofibromin 2 (merlin) |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PAX8 | paired box 8 |
| PCDHB17P | protocadherin beta 17 pseudogene |
| PCM1 | pericentriolar material 1 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDLIM5 | PDZ and LIM domain 5 |
| PEX16 | peroxisomal biogenesis factor 16 |
| PRAME | preferentially expressed antigen in melanoma |
| PRO2964 | uncharacterized protein PRO2964 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| QPCT | glutaminyl-peptide cyclotransferase |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAPSN | receptor-associated protein of the synapse |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| REST | RE1-silencing transcription factor |
| RFTN1 | raftlin, lipid raft linker 1 |
| RUNX1 | runt-related transcription factor 1 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SH3BP2 | SH3-domain binding protein 2 |
| SLA | Src-like-adaptor |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SPO11 | SPO11 meiotic protein covalently bound to DSB |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| STOM | stomatin |
| THPO | thrombopoietin |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TRIP11 | thyroid hormone receptor interactor 11 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| VIM | vimentin |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACOT8 | acyl-CoA thioesterase 8 |
| ACVR2B | activin A receptor, type IIB |
| AEN | apoptosis enhancing nuclease |
| AGO3 | argonaute RISC catalytic component 3 |
| AHCTF1 | AT hook containing transcription factor 1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARMC6 | armadillo repeat containing 6 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C5 | complement component 5 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCNL2 | cyclin L2 |
| CDC37 | cell division cycle 37 |
| CEP131 | centrosomal protein 131kDa |
| CEP83 | centrosomal protein 83kDa |
| CHMP6 | charged multivesicular body protein 6 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CORO1A | coronin, actin binding protein, 1A |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRBN | cereblon |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) |
| EVPL | envoplakin |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FAM53B | family with sequence similarity 53, member B |
| FILIP1L | filamin A interacting protein 1-like |
| FMO4 | flavin containing monooxygenase 4 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GTF2I | general transcription factor IIi |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H2BE | histone cluster 1, H2be |
| HMHA1 | histocompatibility (minor) HA-1 |
| ICK | intestinal cell (MAK-like) kinase |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 |
| IRX4 | iroquois homeobox 4 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KAT2A | K(lysine) acetyltransferase 2A |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LHX6 | LIM homeobox 6 |
| LOC730101 | uncharacterized LOC730101 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTA2 | metastasis associated 1 family, member 2 |
| MTCL1 | microtubule crosslinking factor 1 |
| NAG18 | NAG18 mRNA |
| NUBPL | nucleotide binding protein-like |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PGP | phosphoglycolate phosphatase |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLA2G15 | phospholipase A2, group XV |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PPOX | protoporphyrinogen oxidase |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| RAB23 | RAB23, member RAS oncogene family |
| RANBP17 | RAN binding protein 17 |
| REEP4 | receptor accessory protein 4 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC41A3 | solute carrier family 41, member 3 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SP1 | Sp1 transcription factor |
| SP140L | SP140 nuclear body protein-like |
| SPHK1 | sphingosine kinase 1 |
| SSFA2 | sperm specific antigen 2 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| SYNJ2BP | synaptojanin 2 binding protein |
| TCTN2 | tectonic family member 2 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM183A | transmembrane protein 183A |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM25 | tripartite motif containing 25 |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USB1 | U6 snRNA biogenesis 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| XYLT2 | xylosyltransferase II |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF516 | zinc finger protein 516 |
| ZNF562 | zinc finger protein 562 |
