papillary renal cell carcinoma (translocation-associated)|This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010] (NCBI Entrez Gene Database, 5546)
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11 genes co-occuring with the biological term prcc in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
