pre-b cell receptor complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. (Gene Ontology, GO_0035369)
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86 proteins co-occuring with the pre-b cell receptor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CD79B CD79b molecule, immunoglobulin-associated beta 2.25278
BLNK B-cell linker 2.24132
BCR breakpoint cluster region 2.04958
VPREB1 pre-B lymphocyte 1 2.04449
PREB prolactin regulatory element binding 2.00765
IGLL1 immunoglobulin lambda-like polypeptide 1 1.89662
BTK Bruton agammaglobulinemia tyrosine kinase 1.83406
EBF1 early B-cell factor 1 1.7502
PAX5 paired box 5 1.58104
IL7 interleukin 7 1.56731
IL7R interleukin 7 receptor 1.51412
RAG2 recombination activating gene 2 1.47966
TCF3 transcription factor 3 1.45816
VPREB3 pre-B lymphocyte 3 1.33413
CD79A CD79a molecule, immunoglobulin-associated alpha 1.32492
SYK spleen tyrosine kinase 1.31573
PAX2 paired box 2 1.30121
RAG1 recombination activating gene 1 1.23505
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 1.2262
CD19 CD19 molecule 1.22464
IRF4 interferon regulatory factor 4 1.20241
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 1.0398
LGALS1 lectin, galactoside-binding, soluble, 1 0.962146
LYN LYN proto-oncogene, Src family tyrosine kinase 0.850206
LAPTM5 lysosomal protein transmembrane 5 0.79927
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.774558
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.761797
POU2AF1 POU class 2 associating factor 1 0.687264
CD5 CD5 molecule 0.685954
BCL6 B-cell CLL/lymphoma 6 0.662072
FNIP1 folliculin interacting protein 1 0.659913
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) 0.655172
KLF13 Kruppel-like factor 13 0.651299
CCND3 cyclin D3 0.63715
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.612048
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker) 0.59896
KLF2 Kruppel-like factor 2 0.528388
WNT16 wingless-type MMTV integration site family, member 16 0.524294
CCND2 cyclin D2 0.490135
KRTAP1-3 keratin associated protein 1-3 0.476429
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) 0.461199
CD93 CD93 molecule 0.456012
GPR162 G protein-coupled receptor 162 0.452029
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.444878
KRTAP1-1 keratin associated protein 1-1 0.432618
PBX1 pre-B-cell leukemia homeobox 1 0.432224
CRLF2 cytokine receptor-like factor 2 0.429465
FOXO1 forkhead box O1 0.418468
DCLRE1C DNA cross-link repair 1C 0.414555
SKAP1 src kinase associated phosphoprotein 1 0.412992
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 0.412601
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.402859
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.390841
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.381969
AFF1 AF4/FMR2 family, member 1 0.376586
LAT2 linker for activation of T cells family, member 2 0.369684
CARD11 caspase recruitment domain family, member 11 0.363949
LAT linker for activation of T cells 0.359371
GFI1B growth factor independent 1B transcription repressor 0.356705
VAV1 vav 1 guanine nucleotide exchange factor 0.352522
PLCG1 phospholipase C, gamma 1 0.337751
IGH immunoglobulin heavy locus 0.332095
IGHV5-51 immunoglobulin heavy variable 5-51 0.329084
JAK3 Janus kinase 3 0.325702
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.311478
PRDM1 PR domain containing 1, with ZNF domain 0.278877
ZFX zinc finger protein, X-linked 0.268969
ADAM15 ADAM metallopeptidase domain 15 0.268237
SOX4 SRY (sex determining region Y)-box 4 0.258745
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.256925
DCXR dicarbonyl/L-xylulose reductase 0.246769
AICDA activation-induced cytidine deaminase 0.244601
MCHR1 melanin-concentrating hormone receptor 1 0.235249
FLT3 fms-related tyrosine kinase 3 0.232029
CD53 CD53 molecule 0.230958
TCL1A T-cell leukemia/lymphoma 1A 0.229176
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 0.227397
CD40 CD40 molecule, TNF receptor superfamily member 5 0.222436
BCL2L1 BCL2-like 1 0.218212
CD22 CD22 molecule 0.21646
CDR2 cerebellar degeneration-related protein 2, 62kDa 0.197993
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.194371
FYB FYN binding protein 0.190175
CR2 complement component (3d/Epstein Barr virus) receptor 2 0.178877
EGR2 early growth response 2 0.169099
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.160456