pre-t cell receptor complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A receptor complex found on immature T cells consisting of a T cell receptor beta chain and the pre-TCR-alpha chain, along with additional signaling components including CD3 family members and additional signaling proteins. (Gene Ontology, GO_0043384)
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Genes

109 proteins co-occuring with the pre-t cell receptor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
TRAC T cell receptor alpha constant 2.20445
CD4 CD4 molecule 1.91326
RAG2 recombination activating gene 2 1.75531
CD3G CD3g molecule, gamma (CD3-TCR complex) 1.70878
LCK LCK proto-oncogene, Src family tyrosine kinase 1.66901
NOTCH1 notch 1 1.50735
CD3D CD3d molecule, delta (CD3-TCR complex) 1.474
RAG1 recombination activating gene 1 1.44686
PTCRA pre T-cell antigen receptor alpha 1.43669
TCF3 transcription factor 3 1.36417
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 1.36252
NOTCH3 notch 3 1.33033
NOTCH4 notch 4 1.24707
TCF12 transcription factor 12 1.17004
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 1.16799
CD44 CD44 molecule (Indian blood group) 1.13829
CD247 CD247 molecule 1.10002
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.05488
IL7 interleukin 7 0.970814
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.944007
IL7R interleukin 7 receptor 0.896257
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 0.866287
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.844696
EGR3 early growth response 3 0.836433
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.830007
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.807982
CCR9 chemokine (C-C motif) receptor 9 0.774101
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.707924
NRARP NOTCH-regulated ankyrin repeat protein 0.692078
DLL1 delta-like 1 (Drosophila) 0.685517
TAL1 T-cell acute lymphocytic leukemia 1 0.680284
MIR181C microRNA 181c 0.676803
GIMAP4 GTPase, IMAP family member 4 0.640145
SOS2 son of sevenless homolog 2 (Drosophila) 0.612895
CCL25 chemokine (C-C motif) ligand 25 0.612048
NKAP NFKB activating protein 0.600223
SYK spleen tyrosine kinase 0.597697
FYN FYN proto-oncogene, Src family tyrosine kinase 0.595593
DLL4 delta-like 4 (Drosophila) 0.583012
BCL2A1 BCL2-related protein A1 0.582176
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 0.574662
PRSS16 protease, serine, 16 (thymus) 0.566754
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11 0.565508
DLK1 delta-like 1 homolog (Drosophila) 0.561772
LMO1 LIM domain only 1 (rhombotin 1) 0.5568
CD27 CD27 molecule 0.547297
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.546885
HYI hydroxypyruvate isomerase (putative) 0.53906
CD69 CD69 molecule 0.53454
RORC RAR-related orphan receptor C 0.525522
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.516532
VAV1 vav 1 guanine nucleotide exchange factor 0.512455
PLCG1 phospholipase C, gamma 1 0.486096
LAT linker for activation of T cells 0.481258
GLI2 GLI family zinc finger 2 0.479245
THEMIS thymocyte selection associated 0.477636
CD5 CD5 molecule 0.477233
FLT3 fms-related tyrosine kinase 3 0.4676
ZNF148 zinc finger protein 148 0.458006
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 0.434591
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 0.430647
EGR1 early growth response 1 0.403248
TP53 tumor protein p53 0.398975
CLPS colipase, pancreatic 0.387751
TXK TXK tyrosine kinase 0.373516
CXCL12 chemokine (C-X-C motif) ligand 12 0.372366
HELLS helicase, lymphoid-specific 0.352522
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.345314
BCL2L1 BCL2-like 1 0.339261
SH3KBP1 SH3-domain kinase binding protein 1 0.328708
UNC119 unc-119 homolog (C. elegans) 0.325327
GLI3 GLI family zinc finger 3 0.31783
CXCR4 chemokine (C-X-C motif) receptor 4 0.315586
KIDINS220 kinase D-interacting substrate, 220kDa 0.301425
CD7 CD7 molecule 0.294378
FOXP3 forkhead box P3 0.285138
CD48 CD48 molecule 0.276304
SOS1 son of sevenless homolog 1 (Drosophila) 0.273367
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.269701
PTEN phosphatase and tensin homolog 0.267139
LAT2 linker for activation of T cells family, member 2 0.259473
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.256561
NUMB numb homolog (Drosophila) 0.238837
RGS1 regulator of G-protein signaling 1 0.238478
FADD Fas (TNFRSF6)-associated via death domain 0.232744
DOCK2 dedicator of cytokinesis 2 0.231672
EPHA7 EPH receptor A7 0.229532
CACYBP calcyclin binding protein 0.227041
PREB prolactin regulatory element binding 0.225976
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 0.220673
MAML1 mastermind-like 1 (Drosophila) 0.21681
IL2RA interleukin 2 receptor, alpha 0.198325
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.193719
SMO smoothened, frizzled class receptor 0.187646
CD1D CD1d molecule 0.187646
DGKA diacylglycerol kinase, alpha 80kDa 0.185777
DOCK5 dedicator of cytokinesis 5 0.185469
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.184547
CD37 CD37 molecule 0.183935
FOXN1 forkhead box N1 0.181823
BCR breakpoint cluster region 0.181524
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.181227
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.175188
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.17141
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.163865
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.163865
CD38 CD38 molecule 0.16342
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.162546
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.156863