prediabetes syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

169 genes co-occuring with the disease prediabetes syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
INS insulin 2.1608
CRP C-reactive protein, pentraxin-related 1.32017
HSF5 heat shock transcription factor family member 5 1.21608
SLC30A8 solute carrier family 30 (zinc transporter), member 8 1.07614
GCG glucagon 1.0648
FNDC5 fibronectin type III domain containing 5 0.978848
LEP leptin 0.975903
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.968761
DPP4 dipeptidyl-peptidase 4 0.961634
TRBV19 T cell receptor beta variable 19 0.911845
MTNR1B melatonin receptor 1B 0.911433
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.842982
TCF7 transcription factor 7 (T-cell specific, HMG-box) 0.829049
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A 0.825358
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G 0.808129
ALB albumin 0.795411
COG2 component of oligomeric golgi complex 2 0.789672
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.754527
MTMR9 myotubularin related protein 9 0.749237
VPREB1 pre-B lymphocyte 1 0.74761
GGT1 gamma-glutamyltransferase 1 0.734622
ZFR zinc finger RNA binding protein 0.703938
CPA2 carboxypeptidase A2 (pancreatic) 0.689492
C1QTNF9 C1q and tumor necrosis factor related protein 9 0.678302
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 0.671925
PPARG peroxisome proliferator-activated receptor gamma 0.649323
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 0.634742
ACE angiotensin I converting enzyme 0.633563
IRS1 insulin receptor substrate 1 0.612011
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.608885
GGT2 gamma-glutamyltransferase 2 0.606543
MIR191 microRNA 191 0.60264
IL6 interleukin 6 0.596012
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 0.547419
GIP gastric inhibitory polypeptide 0.545093
C2CD4B C2 calcium-dependent domain containing 4B 0.544705
KCTD15 potassium channel tetramerization domain containing 15 0.543542
TSPAN8 tetraspanin 8 0.542767
DGKB diacylglycerol kinase, beta 90kDa 0.540055
APOB apolipoprotein B 0.536957
GCK glucokinase (hexokinase 4) 0.535409
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.534248
INSR insulin receptor 0.531154
PRDX4 peroxiredoxin 4 0.529608
GHRL ghrelin/obestatin prepropeptide 0.520346
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.517265
TXNIP thioredoxin interacting protein 0.511496
HHEX hematopoietically expressed homeobox 0.510728
RAB10 RAB10, member RAS oncogene family 0.504207
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.497321
FOXO6 forkhead box O6 0.483604
GNPDA2 glucosamine-6-phosphate deaminase 2 0.471846
SIK2 salt-inducible kinase 2 0.469197
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.46466
PRDM16 PR domain containing 16 0.463905
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.462394
CDC123 cell division cycle 123 0.43753
NKX6-1 NK6 homeobox 1 0.42739
MIR186 microRNA 186 0.424389
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 0.421765
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.42139
TES testin LIM domain protein 0.420641
BGLAP bone gamma-carboxyglutamate (gla) protein 0.413527
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.411657
FOXJ2 forkhead box J2 0.408666
RBP4 retinol binding protein 4, plasma 0.406425
INSM2 insulinoma-associated 2 0.406051
SELE selectin E 0.401199
IDE insulin-degrading enzyme 0.397471
C7ORF49 chromosome 7 open reading frame 49 0.393001
NEGR1 neuronal growth regulator 1 0.392629
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.392629
GRK5 G protein-coupled receptor kinase 5 0.391885
ICAM1 intercellular adhesion molecule 1 0.391513
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 0.390769
CPA1 carboxypeptidase A1 (pancreatic) 0.389281
DACH1 dachshund family transcription factor 1 0.385936
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.378514
LEPR leptin receptor 0.37629
CNOT1 CCR4-NOT transcription complex, subunit 1 0.368888
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) 0.360026
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.355972
TMEM27 transmembrane protein 27 0.355235
GLP1R glucagon-like peptide 1 receptor 0.353763
SYNM synemin, intermediate filament protein 0.352291
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 0.350084
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.349349
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.336144
HIRA histone cell cycle regulator 0.335046
PTPRD protein tyrosine phosphatase, receptor type, D 0.331391
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.328469
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.327375
MIR197 microRNA 197 0.320817
FTL ferritin, light polypeptide 0.317909
FTH1 ferritin, heavy polypeptide 1 0.317909
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.316819
SIRT3 sirtuin 3 0.31464
IAPP islet amyloid polypeptide 0.312827
IFNL2 interferon, lambda 2 0.310652
THADA thyroid adenoma associated 0.303059
PRG4 proteoglycan 4 0.300173
RETN resistin 0.298371
GGCT gamma-glutamylcyclotransferase 0.298371
FBXO42 F-box protein 42 0.296211
ADCY2 adenylate cyclase 2 (brain) 0.29118
SIRT1 sirtuin 1 0.287952
AHSG alpha-2-HS-glycoprotein 0.283297
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.280796
CELA2A chymotrypsin-like elastase family, member 2A 0.277584
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.269043
SOCS3 suppressor of cytokine signaling 3 0.265849
LIPE lipase, hormone-sensitive 0.25983
CHAD chondroadherin 0.259124
GLIS3 GLIS family zinc finger 3 0.258064
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.257358
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 0.254888
BCHE butyrylcholinesterase 0.251718
LAD1 ladinin 1 0.247501
CST3 cystatin C 0.242245
LPA lipoprotein, Lp(a) 0.240847
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.240148
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.237357
COL9A2 collagen, type IX, alpha 2 0.235964
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.232836
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 0.229716
HES4 hes family bHLH transcription factor 4 0.224884
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 0.22454
TNF tumor necrosis factor 0.22454
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.222479
GCH1 GTP cyclohydrolase 1 0.222136
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.221793
MDH1 malate dehydrogenase 1, NAD (soluble) 0.219398
GCKR glucokinase (hexokinase 4) regulator 0.219398
MIR146A microRNA 146a 0.219057
CAV3 caveolin 3 0.217012
PALLD palladin, cytoskeletal associated protein 0.215992
CFAP74 cilia and flagella associated protein 74 0.214975
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.214636
IGFBP1 insulin-like growth factor binding protein 1 0.213283
ADCY5 adenylate cyclase 5 0.207912
NRF1 nuclear respiratory factor 1 0.205254
CTRC chymotrypsin C (caldecrin) 0.201635
IGF1 insulin-like growth factor 1 (somatomedin C) 0.201308
WFS1 Wolfram syndrome 1 (wolframin) 0.200656
PPARA peroxisome proliferator-activated receptor alpha 0.200331
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.198064
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.19742
CRY2 cryptochrome circadian clock 2 0.192657
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.187719
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.185612
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.185016
CD4 CD4 molecule 0.184424
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.184128
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.182666
SOD2 superoxide dismutase 2, mitochondrial 0.180367
FABP3 fatty acid binding protein 3, muscle and heart 0.177576
AGER advanced glycosylation end product-specific receptor 0.175146
STAP2 signal transducing adaptor family member 2 0.174881
SLC30A10 solute carrier family 30, member 10 0.171785
MIR96 microRNA 96 0.171535
MRS2 MRS2 magnesium transporter 0.170299
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.165435
GIPR gastric inhibitory polypeptide receptor 0.163317
MIR192 microRNA 192 0.163111
VWF von Willebrand factor 0.162109
CCL26 chemokine (C-C motif) ligand 26 0.160021
CS citrate synthase 0.160021
TALDO1 transaldolase 1 0.15948
PON1 paraoxonase 1 0.158097