prednicarbate-3542 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the prednicarbate-3542 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACTL8 actin-like 8
ADCK4 aarF domain containing kinase 4
ADGRE1 adhesion G protein-coupled receptor E1
AHNAK2 AHNAK nucleoprotein 2
AMACR alpha-methylacyl-CoA racemase
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATXN2L ataxin 2-like
BCAM basal cell adhesion molecule (Lutheran blood group)
BCL6 B-cell CLL/lymphoma 6
BCL9 B-cell CLL/lymphoma 9
C1ORF159 chromosome 1 open reading frame 159
CARD9 caspase recruitment domain family, member 9
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD82 CD82 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDY1 chromodomain protein, Y-linked, 1
CES3 carboxylesterase 3
CFLAR CASP8 and FADD-like apoptosis regulator
CLEC11A C-type lectin domain family 11, member A
CNN1 calponin 1, basic, smooth muscle
COL5A1 collagen, type V, alpha 1
CORO7 coronin 7
DDIT3 DNA-damage-inducible transcript 3
DMTN dematin actin binding protein
DNAH17 dynein, axonemal, heavy chain 17
DNALI1 dynein, axonemal, light intermediate chain 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOCK4 dedicator of cytokinesis 4
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDN2 endothelin 2
EDNRA endothelin receptor type A
ETV5 ets variant 5
EWSR1 EWS RNA-binding protein 1
FAIM2 Fas apoptotic inhibitory molecule 2
GOSR2 golgi SNAP receptor complex member 2
GPR21 G protein-coupled receptor 21
HAMP hepcidin antimicrobial peptide
ICA1 islet cell autoantigen 1, 69kDa
ICOSLG inducible T-cell co-stimulator ligand
IGLJ3 immunoglobulin lambda joining 3
IQCK IQ motif containing K
IRS2 insulin receptor substrate 2
KMT2A lysine (K)-specific methyltransferase 2A
KRT31 keratin 31, type I
LRP12 low density lipoprotein receptor-related protein 12
LRRN2 leucine rich repeat neuronal 2
MALT1 MALT1 paracaspase
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARS methionyl-tRNA synthetase
MBD1 methyl-CpG binding domain protein 1
MFGE8 milk fat globule-EGF factor 8 protein
MID1 midline 1
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MTSS1 metastasis suppressor 1
MTSS1L metastasis suppressor 1-like
NAT6 N-acetyltransferase 6 (GCN5-related)
NPY neuropeptide Y
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OLFML2A olfactomedin-like 2A
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSGIN1 oxidative stress induced growth inhibitor 1
PAX8 paired box 8
PCDHA5 protocadherin alpha 5
PIP prolactin-induced protein
PLAT plasminogen activator, tissue
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRX periaxin
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PXN paxillin
R3HDM1 R3H domain containing 1
RGS2 regulator of G-protein signaling 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIN1 Ras and Rab interactor 1
RNF208 ring finger protein 208
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SERGEF secretion regulating guanine nucleotide exchange factor
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SP100 SP100 nuclear antigen
SRP72 signal recognition particle 72kDa
TBXA2R thromboxane A2 receptor
TCP11L1 t-complex 11, testis-specific-like 1
TGFB2 transforming growth factor, beta 2
TLR2 toll-like receptor 2
TPD52 tumor protein D52
TRAC T cell receptor alpha constant
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TTC38 tetratricopeptide repeat domain 38
TWISTNB TWIST neighbor
VAMP5 vesicle-associated membrane protein 5
VASH2 vasohibin 2
VIPR1 vasoactive intestinal peptide receptor 1
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABHD17B abhydrolase domain containing 17B
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACSL4 acyl-CoA synthetase long-chain family member 4
ADGRE5 adhesion G protein-coupled receptor E5
ADGRG2 adhesion G protein-coupled receptor G2
ADM adrenomedullin
ADTRP androgen-dependent TFPI-regulating protein
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARID3A AT rich interactive domain 3A (BRIGHT-like)
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BANK1 B-cell scaffold protein with ankyrin repeats 1
BIRC7 baculoviral IAP repeat containing 7
C10ORF95 chromosome 10 open reading frame 95
C11ORF68 chromosome 11 open reading frame 68
C17ORF80 chromosome 17 open reading frame 80
C19ORF73 chromosome 19 open reading frame 73
C1ORF105 chromosome 1 open reading frame 105
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC121 coiled-coil domain containing 121
CIDEB cell death-inducing DFFA-like effector b
CLSTN2 calsyntenin 2
CST6 cystatin E/M
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
EFNA3 ephrin-A3
ERN2 endoplasmic reticulum to nucleus signaling 2
FKBP5 FK506 binding protein 5
FRK fyn-related Src family tyrosine kinase
FRMD1 FERM domain containing 1
GAMT guanidinoacetate N-methyltransferase
GCHFR GTP cyclohydrolase I feedback regulator
GMPR guanosine monophosphate reductase
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GRIP2 glutamate receptor interacting protein 2
GTPBP2 GTP binding protein 2
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
IGFBP6 insulin-like growth factor binding protein 6
INCENP inner centromere protein antigens 135/155kDa
INPP1 inositol polyphosphate-1-phosphatase
INPP5J inositol polyphosphate-5-phosphatase J
IRF1 interferon regulatory factor 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
LAX1 lymphocyte transmembrane adaptor 1
LRP2 low density lipoprotein receptor-related protein 2
LY6D lymphocyte antigen 6 complex, locus D
MAGEA6 melanoma antigen family A6
MAGEH1 melanoma antigen family H1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MCC mutated in colorectal cancers
MCOLN1 mucolipin 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NLRX1 NLR family member X1
NNAT neuronatin
NPFFR1 neuropeptide FF receptor 1
NPTX1 neuronal pentraxin I
NYNRIN NYN domain and retroviral integrase containing
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCDHB13 protocadherin beta 13
PDE8B phosphodiesterase 8B
PNPLA6 patatin-like phospholipase domain containing 6
POM121 POM121 transmembrane nucleoporin
POPDC3 popeye domain containing 3
PPT2 palmitoyl-protein thioesterase 2
PRODH proline dehydrogenase (oxidase) 1
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB4B RAB4B, member RAS oncogene family
RASL11B RAS-like, family 11, member B
RGS20 regulator of G-protein signaling 20
RNF126P1 ring finger protein 126 pseudogene 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPAP1 RNA polymerase II associated protein 1
RPL10L ribosomal protein L10-like
SCRN3 secernin 3
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
STARD3 StAR-related lipid transfer (START) domain containing 3
STX1A syntaxin 1A (brain)
TBX19 T-box 19
TCTN2 tectonic family member 2
TSC22D4 TSC22 domain family, member 4
TSPYL2 TSPY-like 2
TTLL1 tubulin tyrosine ligase-like family member 1
TUBB7P tubulin, beta 7, pseudogene
UNC119 unc-119 homolog (C. elegans)
VASH1 vasohibin 1
VAX2 ventral anterior homeobox 2
VEZT vezatin, adherens junctions transmembrane protein
WDR76 WD repeat domain 76
WLS wntless Wnt ligand secretion mediator
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZBTB6 zinc finger and BTB domain containing 6
ZNF205 zinc finger protein 205
ZNF253 zinc finger protein 253
ZNF442 zinc finger protein 442
ZNF747 zinc finger protein 747