| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the prednicarbate-3542 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ACTL8 | actin-like 8 |
| ADCK4 | aarF domain containing kinase 4 |
| ADGRE1 | adhesion G protein-coupled receptor E1 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AMACR | alpha-methylacyl-CoA racemase |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| ATXN2L | ataxin 2-like |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BCL6 | B-cell CLL/lymphoma 6 |
| BCL9 | B-cell CLL/lymphoma 9 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CARD9 | caspase recruitment domain family, member 9 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD82 | CD82 molecule |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
| CDY1 | chromodomain protein, Y-linked, 1 |
| CES3 | carboxylesterase 3 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLEC11A | C-type lectin domain family 11, member A |
| CNN1 | calponin 1, basic, smooth muscle |
| COL5A1 | collagen, type V, alpha 1 |
| CORO7 | coronin 7 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DMTN | dematin actin binding protein |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOCK4 | dedicator of cytokinesis 4 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| EDN2 | endothelin 2 |
| EDNRA | endothelin receptor type A |
| ETV5 | ets variant 5 |
| EWSR1 | EWS RNA-binding protein 1 |
| FAIM2 | Fas apoptotic inhibitory molecule 2 |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPR21 | G protein-coupled receptor 21 |
| HAMP | hepcidin antimicrobial peptide |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IQCK | IQ motif containing K |
| IRS2 | insulin receptor substrate 2 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| KRT31 | keratin 31, type I |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LRRN2 | leucine rich repeat neuronal 2 |
| MALT1 | MALT1 paracaspase |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MARS | methionyl-tRNA synthetase |
| MBD1 | methyl-CpG binding domain protein 1 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MID1 | midline 1 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MTSS1 | metastasis suppressor 1 |
| MTSS1L | metastasis suppressor 1-like |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NPY | neuropeptide Y |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OLFML2A | olfactomedin-like 2A |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PAX8 | paired box 8 |
| PCDHA5 | protocadherin alpha 5 |
| PIP | prolactin-induced protein |
| PLAT | plasminogen activator, tissue |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRX | periaxin |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PXN | paxillin |
| R3HDM1 | R3H domain containing 1 |
| RGS2 | regulator of G-protein signaling 2 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIN1 | Ras and Rab interactor 1 |
| RNF208 | ring finger protein 208 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SP100 | SP100 nuclear antigen |
| SRP72 | signal recognition particle 72kDa |
| TBXA2R | thromboxane A2 receptor |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TGFB2 | transforming growth factor, beta 2 |
| TLR2 | toll-like receptor 2 |
| TPD52 | tumor protein D52 |
| TRAC | T cell receptor alpha constant |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TWISTNB | TWIST neighbor |
| VAMP5 | vesicle-associated membrane protein 5 |
| VASH2 | vasohibin 2 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ABHD17B | abhydrolase domain containing 17B |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ADM | adrenomedullin |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCDC121 | coiled-coil domain containing 121 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLSTN2 | calsyntenin 2 |
| CST6 | cystatin E/M |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| EFNA3 | ephrin-A3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FKBP5 | FK506 binding protein 5 |
| FRK | fyn-related Src family tyrosine kinase |
| FRMD1 | FERM domain containing 1 |
| GAMT | guanidinoacetate N-methyltransferase |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GMPR | guanosine monophosphate reductase |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GTPBP2 | GTP binding protein 2 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| INCENP | inner centromere protein antigens 135/155kDa |
| INPP1 | inositol polyphosphate-1-phosphatase |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IRF1 | interferon regulatory factor 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAGEA6 | melanoma antigen family A6 |
| MAGEH1 | melanoma antigen family H1 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MCC | mutated in colorectal cancers |
| MCOLN1 | mucolipin 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NLRX1 | NLR family member X1 |
| NNAT | neuronatin |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPTX1 | neuronal pentraxin I |
| NYNRIN | NYN domain and retroviral integrase containing |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PCDHB13 | protocadherin beta 13 |
| PDE8B | phosphodiesterase 8B |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| POM121 | POM121 transmembrane nucleoporin |
| POPDC3 | popeye domain containing 3 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RAB4B | RAB4B, member RAS oncogene family |
| RASL11B | RAS-like, family 11, member B |
| RGS20 | regulator of G-protein signaling 20 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL10L | ribosomal protein L10-like |
| SCRN3 | secernin 3 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STX1A | syntaxin 1A (brain) |
| TBX19 | T-box 19 |
| TCTN2 | tectonic family member 2 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSPYL2 | TSPY-like 2 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBB7P | tubulin, beta 7, pseudogene |
| UNC119 | unc-119 homolog (C. elegans) |
| VASH1 | vasohibin 1 |
| VAX2 | ventral anterior homeobox 2 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WDR76 | WD repeat domain 76 |
| WLS | wntless Wnt ligand secretion mediator |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF205 | zinc finger protein 205 |
| ZNF253 | zinc finger protein 253 |
| ZNF442 | zinc finger protein 442 |
| ZNF747 | zinc finger protein 747 |