prednicarbate-5119 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the prednicarbate-5119 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ADGRB1 adhesion G protein-coupled receptor B1
ANGPTL4 angiopoietin-like 4
AOC2 amine oxidase, copper containing 2 (retina-specific)
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
BDKRB2 bradykinin receptor B2
C14ORF79 chromosome 14 open reading frame 79
C1ORF54 chromosome 1 open reading frame 54
C9ORF9 chromosome 9 open reading frame 9
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CADM3 cell adhesion molecule 3
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CD40 CD40 molecule, TNF receptor superfamily member 5
CD82 CD82 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CPA2 carboxypeptidase A2 (pancreatic)
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DCTN2 dynactin 2 (p50)
DGCR2 DiGeorge syndrome critical region gene 2
DKFZP434L187 uncharacterized LOC26082
DKKL1 dickkopf-like 1
DMP1 dentin matrix acidic phosphoprotein 1
DOK4 docking protein 4
DTNA dystrobrevin, alpha
DTX2 deltex 2, E3 ubiquitin ligase
DUSP1 dual specificity phosphatase 1
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FABP4 fatty acid binding protein 4, adipocyte
FAM65B family with sequence similarity 65, member B
FDPS farnesyl diphosphate synthase
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GPR1 G protein-coupled receptor 1
HOXD13 homeobox D13
HRH2 histamine receptor H2
HSPA12A heat shock 70kDa protein 12A
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
ICA1 islet cell autoantigen 1, 69kDa
IGHD immunoglobulin heavy constant delta
ING4 inhibitor of growth family, member 4
IRAK3 interleukin-1 receptor-associated kinase 3
ITGB7 integrin, beta 7
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KRTAP1-3 keratin associated protein 1-3
LENEP lens epithelial protein
LMOD1 leiomodin 1 (smooth muscle)
LTC4S leukotriene C4 synthase
MAL mal, T-cell differentiation protein
MFAP5 microfibrillar associated protein 5
MPPE1 metallophosphoesterase 1
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NNMT nicotinamide N-methyltransferase
NOS1 nitric oxide synthase 1 (neuronal)
OAZ3 ornithine decarboxylase antizyme 3
PAX2 paired box 2
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLXNC1 plexin C1
PRLR prolactin receptor
PRSS53 protease, serine, 53
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPRH protein tyrosine phosphatase, receptor type, H
RBBP9 retinoblastoma binding protein 9
RCE1 Ras converting CAAX endopeptidase 1
RGCC regulator of cell cycle
RGS12 regulator of G-protein signaling 12
RPS4Y1 ribosomal protein S4, Y-linked 1
SAA3P serum amyloid A3 pseudogene
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERGEF secretion regulating guanine nucleotide exchange factor
SFTPB surfactant protein B
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SRPK3 SRSF protein kinase 3
STK38 serine/threonine kinase 38
TBX2 T-box 2
THSD4 thrombospondin, type I, domain containing 4
TMEM231 transmembrane protein 231
TMPRSS4 transmembrane protease, serine 4
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TRPC7 transient receptor potential cation channel, subfamily C, member 7
ULBP1 UL16 binding protein 1
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
XAF1 XIAP associated factor 1
ZC3H7B zinc finger CCCH-type containing 7B
ZNF484 zinc finger protein 484

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADGRB2 adhesion G protein-coupled receptor B2
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
AMDHD2 amidohydrolase domain containing 2
APOLD1 apolipoprotein L domain containing 1
ARHGAP10 Rho GTPase activating protein 10
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATAD5 ATPase family, AAA domain containing 5
BBS1 Bardet-Biedl syndrome 1
BCL2L2 BCL2-like 2
BFSP1 beaded filament structural protein 1, filensin
BTC betacellulin
C11ORF30 chromosome 11 open reading frame 30
C7ORF43 chromosome 7 open reading frame 43
C9ORF40 chromosome 9 open reading frame 40
CHST10 carbohydrate sulfotransferase 10
CISH cytokine inducible SH2-containing protein
CLDN15 claudin 15
CTSO cathepsin O
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCAF17 DDB1 and CUL4 associated factor 17
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DENND4A DENN/MADD domain containing 4A
ECM1 extracellular matrix protein 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
EPHB3 EPH receptor B3
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FUZ fuzzy planar cell polarity protein
FZD8 frizzled class receptor 8
GPR39 G protein-coupled receptor 39
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GTF2I general transcription factor IIi
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H1T histone cluster 1, H1t
IL24 interleukin 24
KDM5C lysine (K)-specific demethylase 5C
KIAA0319L KIAA0319-like
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC61 leucine rich repeat containing 61
LYPD1 LY6/PLAUR domain containing 1
MBTD1 mbt domain containing 1
MCC mutated in colorectal cancers
MGC12488
MUC3B mucin 3B, cell surface associated
MX1 MX dynamin-like GTPase 1
NACA2 nascent polypeptide-associated complex alpha subunit 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOD1 nucleotide-binding oligomerization domain containing 1
NPY1R neuropeptide Y receptor Y1
NXPH4 neurexophilin 4
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PALMD palmdelphin
PCOLCE procollagen C-endopeptidase enhancer
PER3 period circadian clock 3
PEX26 peroxisomal biogenesis factor 26
PGPEP1 pyroglutamyl-peptidase I
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLAU plasminogen activator, urokinase
POLL polymerase (DNA directed), lambda
PRKG2 protein kinase, cGMP-dependent, type II
PTGFR prostaglandin F receptor (FP)
QSER1 glutamine and serine rich 1
RAB3A RAB3A, member RAS oncogene family
RNF126P1 ring finger protein 126 pseudogene 1
RNF31 ring finger protein 31
RPL23AP32 ribosomal protein L23a pseudogene 32
SCIN scinderin
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SHPK sedoheptulokinase
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC35F6 solute carrier family 35, member F6
SLC46A3 solute carrier family 46, member 3
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SND1-IT1 SND1 intronic transcript 1
STK16 serine/threonine kinase 16
TBX19 T-box 19
TBXAS1 thromboxane A synthase 1 (platelet)
TENM4 teneurin transmembrane protein 4
TMEM2 transmembrane protein 2
TRIM52 tripartite motif containing 52
TXK TXK tyrosine kinase
UBQLN4 ubiquilin 4
USP27X ubiquitin specific peptidase 27, X-linked
WDR33 WD repeat domain 33
ZBTB25 zinc finger and BTB domain containing 25
ZBTB48 zinc finger and BTB domain containing 48
ZBTB6 zinc finger and BTB domain containing 6
ZFP30 ZFP30 zinc finger protein
ZNF197 zinc finger protein 197
ZNF225 zinc finger protein 225
ZNF286A zinc finger protein 286A
ZNF671 zinc finger protein 671
ZNF74 zinc finger protein 74
ZNF84 zinc finger protein 84
ZW10 zw10 kinetochore protein