prednicarbate-5544 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the prednicarbate-5544 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AFAP1 actin filament associated protein 1
ANK2 ankyrin 2, neuronal
ANKRD7 ankyrin repeat domain 7
ASIC2 acid sensing (proton gated) ion channel 2
BGN biglycan
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF63 chromosome 11 open reading frame 63
CABP2 calcium binding protein 2
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCDC71 coiled-coil domain containing 71
CCRL2 chemokine (C-C motif) receptor-like 2
CD86 CD86 molecule
CDC14B cell division cycle 14B
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CNTNAP2 contactin associated protein-like 2
CYLD cylindromatosis (turban tumor syndrome)
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDIT3 DNA-damage-inducible transcript 3
DEAF1 DEAF1 transcription factor
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNAH17 dynein, axonemal, heavy chain 17
DZIP3 DAZ interacting zinc finger protein 3
EIF3F eukaryotic translation initiation factor 3, subunit F
ELOVL2 ELOVL fatty acid elongase 2
EPOR erythropoietin receptor
FAM46C family with sequence similarity 46, member C
FKBP8 FK506 binding protein 8, 38kDa
FSCN1 fascin actin-bundling protein 1
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GBP1 guanylate binding protein 1, interferon-inducible
GP2 glycoprotein 2 (zymogen granule membrane)
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
GPR22 G protein-coupled receptor 22
GSK3A glycogen synthase kinase 3 alpha
GSTP1 glutathione S-transferase pi 1
HIST1H1E histone cluster 1, H1e
HLA-J major histocompatibility complex, class I, J (pseudogene)
HNF1B HNF1 homeobox B
HOXB6 homeobox B6
ICAM1 intercellular adhesion molecule 1
IFT38 intraflagellar transport 38
IPW imprinted in Prader-Willi syndrome (non-protein coding)
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRS2 insulin receptor substrate 2
ISL1 ISL LIM homeobox 1
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KIF13A kinesin family member 13A
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRRC61 leucine rich repeat containing 61
LY9 lymphocyte antigen 9
MERTK MER proto-oncogene, tyrosine kinase
NLGN4X neuroligin 4, X-linked
NOX1 NADPH oxidase 1
NPR1 natriuretic peptide receptor 1
NRIP3 nuclear receptor interacting protein 3
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
PCDHB3 protocadherin beta 3
PDE4C phosphodiesterase 4C, cAMP-specific
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PIGR polymeric immunoglobulin receptor
PRKCE protein kinase C, epsilon
PSD3 pleckstrin and Sec7 domain containing 3
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RGCC regulator of cell cycle
RHEB Ras homolog enriched in brain
SCAND2P SCAN domain containing 2 pseudogene
SERHL2 serine hydrolase-like 2
SGK2 serum/glucocorticoid regulated kinase 2
SHOX2 short stature homeobox 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC35E2 solute carrier family 35, member E2
SMTN smoothelin
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SSX3 synovial sarcoma, X breakpoint 3
STIM1 stromal interaction molecule 1
SYN2 synapsin II
TCP11L1 t-complex 11, testis-specific-like 1
TEX40 testis expressed 40
TLDC1 TBC/LysM-associated domain containing 1
TMEM63A transmembrane protein 63A
TPMT thiopurine S-methyltransferase
VCAN versican
VNN2 vanin 2
WIZ widely interspaced zinc finger motifs
WSCD1 WSC domain containing 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XYLT1 xylosyltransferase I
ZIC3 Zic family member 3
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
BAHCC1 BAH domain and coiled-coil containing 1
BCL9 B-cell CLL/lymphoma 9
BIRC7 baculoviral IAP repeat containing 7
BRD9 bromodomain containing 9
CCNL2 cyclin L2
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CEP72 centrosomal protein 72kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHKB choline kinase beta
CHMP6 charged multivesicular body protein 6
CLDN15 claudin 15
CLSPN claspin
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CPSF3L cleavage and polyadenylation specific factor 3-like
DNAL4 dynein, axonemal, light chain 4
EDAR ectodysplasin A receptor
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
FANCC Fanconi anemia, complementation group C
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLCN folliculin
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUF1 GUF1 GTPase homolog (S. cerevisiae)
GUSBP3 glucuronidase, beta pseudogene 3
H2AFY2 H2A histone family, member Y2
HIST1H2BI histone cluster 1, H2bi
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IMPACT impact RWD domain protein
INF2 inverted formin, FH2 and WH2 domain containing
INHBB inhibin, beta B
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCTD7 potassium channel tetramerization domain containing 7
KLHL12 kelch-like family member 12
LAMA3 laminin, alpha 3
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MAP9 microtubule-associated protein 9
MBOAT2 membrane bound O-acyltransferase domain containing 2
MFSD11 major facilitator superfamily domain containing 11
NCSTN nicastrin
NUBPL nucleotide binding protein-like
ONECUT2 one cut homeobox 2
PCDHA9 protocadherin alpha 9
PCNXL4 pecanex-like 4 (Drosophila)
PITX2 paired-like homeodomain 2
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
QPCT glutaminyl-peptide cyclotransferase
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RCOR3 REST corepressor 3
RFTN1 raftlin, lipid raft linker 1
RFX7 regulatory factor X, 7
RIN2 Ras and Rab interactor 2
RNF43 ring finger protein 43
RPL23AP32 ribosomal protein L23a pseudogene 32
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCAI suppressor of cancer cell invasion
SCUBE2 signal peptide, CUB domain, EGF-like 2
SH2B3 SH2B adaptor protein 3
SHCBP1 SHC SH2-domain binding protein 1
SKIL SKI-like proto-oncogene
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMIM14 small integral membrane protein 14
SOWAHC sosondowah ankyrin repeat domain family member C
SPIDR scaffolding protein involved in DNA repair
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
TKFC triokinase/FMN cyclase
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM2 transmembrane protein 2
TMEM242 transmembrane protein 242
TMEM57 transmembrane protein 57
TTC33 tetratricopeptide repeat domain 33
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
WDR62 WD repeat domain 62
WDR76 WD repeat domain 76
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XYLT2 xylosyltransferase II
ZBED1 zinc finger, BED-type containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF394 zinc finger protein 394
ZNF430 zinc finger protein 430
ZNF492 zinc finger protein 492
ZNF573 zinc finger protein 573
ZNF652 zinc finger protein 652
ZNF701 zinc finger protein 701
ZNF721 zinc finger protein 721
ZXDC ZXD family zinc finger C