prednisolone-265 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the prednisolone-265 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
AK1 adenylate kinase 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ARHGAP19 Rho GTPase activating protein 19
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ATG4B autophagy related 4B, cysteine peptidase
ATXN8OS ATXN8 opposite strand (non-protein coding)
BIK BCL2-interacting killer (apoptosis-inducing)
BTD biotinidase
C10ORF76 chromosome 10 open reading frame 76
C22ORF46 chromosome 22 open reading frame 46
CALCRL calcitonin receptor-like
CDK9 cyclin-dependent kinase 9
CEP63 centrosomal protein 63kDa
CHPF2 chondroitin polymerizing factor 2
CLASP2 cytoplasmic linker associated protein 2
CNPY3 canopy FGF signaling regulator 3
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DIXDC1 DIX domain containing 1
DUS2 dihydrouridine synthase 2
DXO decapping exoribonuclease
ERCC1 excision repair cross-complementation group 1
FBLN1 fibulin 1
FGFR2 fibroblast growth factor receptor 2
FNDC3A fibronectin type III domain containing 3A
FXR2 fragile X mental retardation, autosomal homolog 2
GADD45B growth arrest and DNA-damage-inducible, beta
GEMIN4 gem (nuclear organelle) associated protein 4
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
HIPK2 homeodomain interacting protein kinase 2
HIST1H2BD histone cluster 1, H2bd
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA4 heat shock 70kDa protein 4
ICAM2 intercellular adhesion molecule 2
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFI27 interferon, alpha-inducible protein 27
IFNA21 interferon, alpha 21
IFT122 intraflagellar transport 122
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KLHL25 kelch-like family member 25
MON1B MON1 secretory trafficking family member B
MPPE1 metallophosphoesterase 1
N4BP1 NEDD4 binding protein 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NUPL2 nucleoporin like 2
OAZ3 ornithine decarboxylase antizyme 3
PAIP2B poly(A) binding protein interacting protein 2B
PCDHB3 protocadherin beta 3
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLEK pleckstrin
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PPARD peroxisome proliferator-activated receptor delta
PRMT7 protein arginine methyltransferase 7
PTK6 protein tyrosine kinase 6
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
RBM10 RNA binding motif protein 10
RECQL5 RecQ protein-like 5
REPS2 RALBP1 associated Eps domain containing 2
RPL10L ribosomal protein L10-like
RREB1 ras responsive element binding protein 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RUNX1 runt-related transcription factor 1
SAFB scaffold attachment factor B
SBNO2 strawberry notch homolog 2 (Drosophila)
SGK1 serum/glucocorticoid regulated kinase 1
SH2B1 SH2B adaptor protein 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SOX21 SRY (sex determining region Y)-box 21
SPTBN1 spectrin, beta, non-erythrocytic 1
SPTBN2 spectrin, beta, non-erythrocytic 2
STK19 serine/threonine kinase 19
SURF2 surfeit 2
TFE3 transcription factor binding to IGHM enhancer 3
TMPRSS2 transmembrane protease, serine 2
TNK1 tyrosine kinase, non-receptor, 1
TOB2 transducer of ERBB2, 2
TRAFD1 TRAF-type zinc finger domain containing 1
TTLL4 tubulin tyrosine ligase-like family member 4
TTR transthyretin
USP48 ubiquitin specific peptidase 48
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VRK3 vaccinia related kinase 3
WDR13 WD repeat domain 13
WDR18 WD repeat domain 18
XYLT2 xylosyltransferase II
ZNF335 zinc finger protein 335
ZNF668 zinc finger protein 668

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AGMAT agmatine ureohydrolase (agmatinase)
ALOX15B arachidonate 15-lipoxygenase, type B
ANKRD55 ankyrin repeat domain 55
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ASB8 ankyrin repeat and SOCS box containing 8
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
BEST2 bestrophin 2
BTF3P12 basic transcription factor 3 pseudogene 12
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CBX4 chromobox homolog 4
CCDC64 coiled-coil domain containing 64
CD180 CD180 molecule
CD19 CD19 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDR2L cerebellar degeneration-related protein 2-like
CEP97 centrosomal protein 97kDa
CNTNAP1 contactin associated protein 1
COPZ2 coatomer protein complex, subunit zeta 2
CPA3 carboxypeptidase A3 (mast cell)
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DRP2 dystrophin related protein 2
DSE dermatan sulfate epimerase
EAF2 ELL associated factor 2
EMID1 EMI domain containing 1
EPN1 epsin 1
EYA1 EYA transcriptional coactivator and phosphatase 1
FGF17 fibroblast growth factor 17
FGFBP1 fibroblast growth factor binding protein 1
GLB1L galactosidase, beta 1-like
GLDC glycine dehydrogenase (decarboxylating)
GPR15 G protein-coupled receptor 15
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HOPX HOP homeobox
HOXB1 homeobox B1
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IGFALS insulin-like growth factor binding protein, acid labile subunit
IHH indian hedgehog
IL12RB1 interleukin 12 receptor, beta 1
IRF8 interferon regulatory factor 8
ISLR immunoglobulin superfamily containing leucine-rich repeat
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KDM5D lysine (K)-specific demethylase 5D
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KLHL11 kelch-like family member 11
KRT6A keratin 6A, type II
KRT75 keratin 75, type II
LAMP5 lysosomal-associated membrane protein family, member 5
LENEP lens epithelial protein
LINC00652 long intergenic non-protein coding RNA 652
LOC440895 two pore channel 3 pseudogene
LPPR2 lipid phosphate phosphatase-related protein type 2
MAGEC1 melanoma antigen family C1
MAGEC2 melanoma antigen family C2
MC4R melanocortin 4 receptor
MT4 metallothionein 4
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NPY4R neuropeptide Y receptor Y4
ONECUT1 one cut homeobox 1
OR2C1 olfactory receptor, family 2, subfamily C, member 1
OVOL1 ovo-like zinc finger 1
PACS1 phosphofurin acidic cluster sorting protein 1
PCOLCE procollagen C-endopeptidase enhancer
PHC1 polyhomeotic homolog 1 (Drosophila)
PNOC prepronociceptin
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRKG2 protein kinase, cGMP-dependent, type II
PSG2 pregnancy specific beta-1-glycoprotein 2
SCARA3 scavenger receptor class A, member 3
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SMO smoothened, frizzled class receptor
SST somatostatin
STAB2 stabilin 2
STARD8 StAR-related lipid transfer (START) domain containing 8
TMPRSS4 transmembrane protease, serine 4
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TSHZ2 teashirt zinc finger homeobox 2
TSPAN7 tetraspanin 7
TTLL7 tubulin tyrosine ligase-like family member 7
TUBAL3 tubulin, alpha-like 3
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)
VSIG4 V-set and immunoglobulin domain containing 4
YPEL1 yippee-like 1 (Drosophila)
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF134 zinc finger protein 134
ZNF276 zinc finger protein 276
ZNF286A zinc finger protein 286A
ZNF573 zinc finger protein 573
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652