| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the prednisolone-5101 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTN2 | actinin, alpha 2 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADAMTS8 | ADAM metallopeptidase with thrombospondin type 1 motif, 8 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AFAP1 | actin filament associated protein 1 |
| APAF1 | apoptotic peptidase activating factor 1 |
| ARG1 | arginase 1 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ARSD | arylsulfatase D |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BMP4 | bone morphogenetic protein 4 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CCDC7 | coiled-coil domain containing 7 |
| CEMP1 | cementum protein 1 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLIC3 | chloride intracellular channel 3 |
| COL8A1 | collagen, type VIII, alpha 1 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CRLF1 | cytokine receptor-like factor 1 |
| DGKA | diacylglycerol kinase, alpha 80kDa |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EFNB2 | ephrin-B2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM53B | family with sequence similarity 53, member B |
| FBXO31 | F-box protein 31 |
| FGF6 | fibroblast growth factor 6 |
| FLT1 | fms-related tyrosine kinase 1 |
| FRMD1 | FERM domain containing 1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GRK4 | G protein-coupled receptor kinase 4 |
| GRM7 | glutamate receptor, metabotropic 7 |
| HAP1 | huntingtin-associated protein 1 |
| HPSE2 | heparanase 2 (inactive) |
| HSF2BP | heat shock transcription factor 2 binding protein |
| IL16 | interleukin 16 |
| IL6 | interleukin 6 |
| IL6R | interleukin 6 receptor |
| IRAK3 | interleukin-1 receptor-associated kinase 3 |
| JADE2 | jade family PHD finger 2 |
| KDM4B | lysine (K)-specific demethylase 4B |
| LAMA2 | laminin, alpha 2 |
| LDB3 | LIM domain binding 3 |
| LEFTY2 | left-right determination factor 2 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| METTL7A | methyltransferase like 7A |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MMP25 | matrix metallopeptidase 25 |
| MST1 | macrophage stimulating 1 |
| MT1H | metallothionein 1H |
| MYH14 | myosin, heavy chain 14, non-muscle |
| NAV2 | neuron navigator 2 |
| NEK11 | NIMA-related kinase 11 |
| NINL | ninein-like |
| NNMT | nicotinamide N-methyltransferase |
| NOP14-AS1 | NOP14 antisense RNA 1 |
| NRXN2 | neurexin 2 |
| OCA2 | oculocutaneous albinism II |
| OR12D3 | olfactory receptor, family 12, subfamily D, member 3 |
| PER1 | period circadian clock 1 |
| PLAT | plasminogen activator, tissue |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RARG | retinoic acid receptor, gamma |
| RIN3 | Ras and Rab interactor 3 |
| RPS3A | ribosomal protein S3A |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| SVIL | supervillin |
| SYK | spleen tyrosine kinase |
| TAOK1 | TAO kinase 1 |
| TAT | tyrosine aminotransferase |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TRMT1 | tRNA methyltransferase 1 homolog (S. cerevisiae) |
| UBA7 | ubiquitin-like modifier activating enzyme 7 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VN1R1 | vomeronasal 1 receptor 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZIC3 | Zic family member 3 |
| ZNF440 | zinc finger protein 440 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BAG4 | BCL2-associated athanogene 4 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| BCL2A1 | BCL2-related protein A1 |
| BEX1 | brain expressed, X-linked 1 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CCNT1 | cyclin T1 |
| CDH7 | cadherin 7, type 2 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CPA4 | carboxypeptidase A4 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CTSO | cathepsin O |
| DCLRE1A | DNA cross-link repair 1A |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DENND5B | DENN/MADD domain containing 5B |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EHF | ets homologous factor |
| EXOC5 | exocyst complex component 5 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXO46 | F-box protein 46 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPR3 | G protein-coupled receptor 3 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HIST1H2AG | histone cluster 1, H2ag |
| HLX | H2.0-like homeobox |
| HOXA1 | homeobox A1 |
| IFI44L | interferon-induced protein 44-like |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| JUNB | jun B proto-oncogene |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIAA1107 | KIAA1107 |
| LINS | lines homolog (Drosophila) |
| LYRM2 | LYR motif containing 2 |
| MAGEH1 | melanoma antigen family H1 |
| MANEA | mannosidase, endo-alpha |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MMP1 | matrix metallopeptidase 1 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MOXD1 | monooxygenase, DBH-like 1 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PALMD | palmdelphin |
| PAX9 | paired box 9 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| S100A3 | S100 calcium binding protein A3 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMAD7 | SMAD family member 7 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPIN1 | spindlin 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TENM4 | teneurin transmembrane protein 4 |
| TESK1 | testis-specific kinase 1 |
| TEX40 | testis expressed 40 |
| THBS3 | thrombospondin 3 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRIM25 | tripartite motif containing 25 |
| TRPS1 | trichorhinophalangeal syndrome I |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF215 | zinc finger protein 215 |
| ZNF230 | zinc finger protein 230 |
| ZNF254 | zinc finger protein 254 |
| ZNF286A | zinc finger protein 286A |
| ZNF41 | zinc finger protein 41 |
| ZNF668 | zinc finger protein 668 |
| ZNF675 | zinc finger protein 675 |
| ZNF711 | zinc finger protein 711 |