prednisolone-5101 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the prednisolone-5101 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
ADAM22 ADAM metallopeptidase domain 22
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AFAP1 actin filament associated protein 1
APAF1 apoptotic peptidase activating factor 1
ARG1 arginase 1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARMCX4 armadillo repeat containing, X-linked 4
ARPIN actin-related protein 2/3 complex inhibitor
ARSD arylsulfatase D
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
BCL2 B-cell CLL/lymphoma 2
BMP4 bone morphogenetic protein 4
BTF3P11 basic transcription factor 3 pseudogene 11
C14ORF93 chromosome 14 open reading frame 93
C5ORF42 chromosome 5 open reading frame 42
CA5B carbonic anhydrase VB, mitochondrial
CCDC7 coiled-coil domain containing 7
CEMP1 cementum protein 1
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLIC3 chloride intracellular channel 3
COL8A1 collagen, type VIII, alpha 1
CREBZF CREB/ATF bZIP transcription factor
CRLF1 cytokine receptor-like factor 1
DGKA diacylglycerol kinase, alpha 80kDa
E2F4 E2F transcription factor 4, p107/p130-binding
EFNB2 ephrin-B2
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM53B family with sequence similarity 53, member B
FBXO31 F-box protein 31
FGF6 fibroblast growth factor 6
FLT1 fms-related tyrosine kinase 1
FRMD1 FERM domain containing 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GRK4 G protein-coupled receptor kinase 4
GRM7 glutamate receptor, metabotropic 7
HAP1 huntingtin-associated protein 1
HPSE2 heparanase 2 (inactive)
HSF2BP heat shock transcription factor 2 binding protein
IL16 interleukin 16
IL6 interleukin 6
IL6R interleukin 6 receptor
IRAK3 interleukin-1 receptor-associated kinase 3
JADE2 jade family PHD finger 2
KDM4B lysine (K)-specific demethylase 4B
LAMA2 laminin, alpha 2
LDB3 LIM domain binding 3
LEFTY2 left-right determination factor 2
LINC00341 long intergenic non-protein coding RNA 341
LINC00597 long intergenic non-protein coding RNA 597
LRP4 low density lipoprotein receptor-related protein 4
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP2K5 mitogen-activated protein kinase kinase 5
MEG3 maternally expressed 3 (non-protein coding)
METTL7A methyltransferase like 7A
MFSD7 major facilitator superfamily domain containing 7
MIER2 mesoderm induction early response 1, family member 2
MMP25 matrix metallopeptidase 25
MST1 macrophage stimulating 1
MT1H metallothionein 1H
MYH14 myosin, heavy chain 14, non-muscle
NAV2 neuron navigator 2
NEK11 NIMA-related kinase 11
NINL ninein-like
NNMT nicotinamide N-methyltransferase
NOP14-AS1 NOP14 antisense RNA 1
NRXN2 neurexin 2
OCA2 oculocutaneous albinism II
OR12D3 olfactory receptor, family 12, subfamily D, member 3
PER1 period circadian clock 1
PLAT plasminogen activator, tissue
PMFBP1 polyamine modulated factor 1 binding protein 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PSD4 pleckstrin and Sec7 domain containing 4
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RARG retinoic acid receptor, gamma
RIN3 Ras and Rab interactor 3
RPS3A ribosomal protein S3A
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SSX1 synovial sarcoma, X breakpoint 1
SVIL supervillin
SYK spleen tyrosine kinase
TAOK1 TAO kinase 1
TAT tyrosine aminotransferase
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
UBA7 ubiquitin-like modifier activating enzyme 7
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VN1R1 vomeronasal 1 receptor 1
ZER1 zyg-11 related, cell cycle regulator
ZFP36L2 ZFP36 ring finger protein-like 2
ZIC3 Zic family member 3
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
APOLD1 apolipoprotein L domain containing 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BAG4 BCL2-associated athanogene 4
BANK1 B-cell scaffold protein with ankyrin repeats 1
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BCL2A1 BCL2-related protein A1
BEX1 brain expressed, X-linked 1
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C1ORF159 chromosome 1 open reading frame 159
CCNT1 cyclin T1
CDH7 cadherin 7, type 2
CIR1 corepressor interacting with RBPJ, 1
CPA4 carboxypeptidase A4
CPED1 cadherin-like and PC-esterase domain containing 1
CSRNP3 cysteine-serine-rich nuclear protein 3
CTSO cathepsin O
DCLRE1A DNA cross-link repair 1A
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DENND5B DENN/MADD domain containing 5B
DEPTOR DEP domain containing MTOR-interacting protein
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
EDIL3 EGF-like repeats and discoidin I-like domains 3
EHF ets homologous factor
EXOC5 exocyst complex component 5
F3 coagulation factor III (thromboplastin, tissue factor)
FBXL15 F-box and leucine-rich repeat protein 15
FBXO46 F-box protein 46
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FRS2 fibroblast growth factor receptor substrate 2
GMEB1 glucocorticoid modulatory element binding protein 1
GPR3 G protein-coupled receptor 3
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HIST1H2AG histone cluster 1, H2ag
HLX H2.0-like homeobox
HOXA1 homeobox A1
IFI44L interferon-induced protein 44-like
IKZF5 IKAROS family zinc finger 5 (Pegasus)
JUNB jun B proto-oncogene
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA1107 KIAA1107
LINS lines homolog (Drosophila)
LYRM2 LYR motif containing 2
MAGEH1 melanoma antigen family H1
MANEA mannosidase, endo-alpha
MBTPS2 membrane-bound transcription factor peptidase, site 2
MMP1 matrix metallopeptidase 1
MORC3 MORC family CW-type zinc finger 3
MOXD1 monooxygenase, DBH-like 1
NR3C2 nuclear receptor subfamily 3, group C, member 2
OASL 2'-5'-oligoadenylate synthetase-like
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PACS1 phosphofurin acidic cluster sorting protein 1
PAIP2B poly(A) binding protein interacting protein 2B
PALMD palmdelphin
PAX9 paired box 9
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRKG2 protein kinase, cGMP-dependent, type II
PWAR5 Prader Willi/Angelman region RNA 5
R3HCC1L R3H domain and coiled-coil containing 1-like
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RP2 retinitis pigmentosa 2 (X-linked recessive)
S100A3 S100 calcium binding protein A3
SAYSD1 SAYSVFN motif domain containing 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SENP7 SUMO1/sentrin specific peptidase 7
SLC12A8 solute carrier family 12, member 8
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC35F6 solute carrier family 35, member F6
SLC46A3 solute carrier family 46, member 3
SLITRK5 SLIT and NTRK-like family, member 5
SMAD7 SMAD family member 7
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPIN1 spindlin 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBXAS1 thromboxane A synthase 1 (platelet)
TENM4 teneurin transmembrane protein 4
TESK1 testis-specific kinase 1
TEX40 testis expressed 40
THBS3 thrombospondin 3
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM25 tripartite motif containing 25
TRPS1 trichorhinophalangeal syndrome I
ZBTB6 zinc finger and BTB domain containing 6
ZNF215 zinc finger protein 215
ZNF230 zinc finger protein 230
ZNF254 zinc finger protein 254
ZNF286A zinc finger protein 286A
ZNF41 zinc finger protein 41
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675
ZNF711 zinc finger protein 711