| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the prednisolone-5526 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AFF2 | AF4/FMR2 family, member 2 |
| ANTXR1 | anthrax toxin receptor 1 |
| AOX1 | aldehyde oxidase 1 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARHGAP6 | Rho GTPase activating protein 6 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATP10A | ATPase, class V, type 10A |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BICC1 | BicC family RNA binding protein 1 |
| BTD | biotinidase |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CFAP45 | cilia and flagella associated protein 45 |
| CHRNE | cholinergic receptor, nicotinic, epsilon (muscle) |
| CLTA | clathrin, light chain A |
| DAO | D-amino-acid oxidase |
| DCLK2 | doublecortin-like kinase 2 |
| DCT | dopachrome tautomerase |
| DFNA5 | deafness, autosomal dominant 5 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DSC2 | desmocollin 2 |
| DTNA | dystrobrevin, alpha |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EN2 | engrailed homeobox 2 |
| FGF18 | fibroblast growth factor 18 |
| FHL1 | four and a half LIM domains 1 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HBS1L | HBS1-like translational GTPase |
| HDAC5 | histone deacetylase 5 |
| HIST1H1E | histone cluster 1, H1e |
| HMHB1 | histocompatibility (minor) HB-1 |
| HOXC5 | homeobox C5 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HYAL4 | hyaluronoglucosaminidase 4 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ICAM2 | intercellular adhesion molecule 2 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFT122 | intraflagellar transport 122 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| INHBC | inhibin, beta C |
| ISG15 | ISG15 ubiquitin-like modifier |
| KRIT1 | KRIT1, ankyrin repeat containing |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LOC157562 | uncharacterized LOC157562 |
| MAB21L1 | mab-21-like 1 (C. elegans) |
| MAPK10 | mitogen-activated protein kinase 10 |
| MUC3B | mucin 3B, cell surface associated |
| NBEAL2 | neurobeachin-like 2 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NRP2 | neuropilin 2 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PEG10 | paternally expressed 10 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 |
| PITX1 | paired-like homeodomain 1 |
| PLLP | plasmolipin |
| POU4F2 | POU class 4 homeobox 2 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| RPL23AP53 | ribosomal protein L23a pseudogene 53 |
| RUNDC3A | RUN domain containing 3A |
| SAMD4A | sterile alpha motif domain containing 4A |
| SIRT3 | sirtuin 3 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC39A9 | solute carrier family 39, member 9 |
| SMTN | smoothelin |
| SOX15 | SRY (sex determining region Y)-box 15 |
| SRRT | serrate, RNA effector molecule |
| STX1A | syntaxin 1A (brain) |
| SYBU | syntabulin (syntaxin-interacting) |
| TAT | tyrosine aminotransferase |
| TEX14 | testis expressed 14 |
| TMEM63A | transmembrane protein 63A |
| TRIM15 | tripartite motif containing 15 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| TUBA3C | tubulin, alpha 3c |
| UNC119 | unc-119 homolog (C. elegans) |
| UTRN | utrophin |
| WDR55 | WD repeat domain 55 |
| WDR59 | WD repeat domain 59 |
| WIZ | widely interspaced zinc finger motifs |
| ZNF639 | zinc finger protein 639 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATG9A | autophagy related 9A |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNL2 | cyclin L2 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CENPC | centromere protein C |
| CENPO | centromere protein O |
| CHKB | choline kinase beta |
| CHST10 | carbohydrate sulfotransferase 10 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLDN15 | claudin 15 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CTAGE9 | CTAGE family, member 9 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| FAM110B | family with sequence similarity 110, member B |
| FAM155B | family with sequence similarity 155, member B |
| FAM169A | family with sequence similarity 169, member A |
| FOCAD | focadhesin |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GID4 | GID complex subunit 4 |
| GLOD4 | glyoxalase domain containing 4 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPATCH2L | G patch domain containing 2-like |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AL | histone cluster 1, H2al |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H3G | histone cluster 1, H3g |
| HSPA2 | heat shock 70kDa protein 2 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MICALL2 | MICAL-like 2 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NLRX1 | NLR family member X1 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NUBPL | nucleotide binding protein-like |
| PADI2 | peptidyl arginine deiminase, type II |
| PIGA | phosphatidylinositol glycan anchor biosynthesis, class A |
| PLA2G15 | phospholipase A2, group XV |
| PLEK2 | pleckstrin 2 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLIN3 | perilipin 3 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PRSS22 | protease, serine, 22 |
| RAB33B | RAB33B, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RCOR3 | REST corepressor 3 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF170 | ring finger protein 170 |
| S100A6 | S100 calcium binding protein A6 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SHPK | sedoheptulokinase |
| SIRT6 | sirtuin 6 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TGFBR3 | transforming growth factor, beta receptor III |
| TMEM51 | transmembrane protein 51 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TTC30A | tetratricopeptide repeat domain 30A |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| WDR19 | WD repeat domain 19 |
| XYLT2 | xylosyltransferase II |
| YIPF5 | Yip1 domain family, member 5 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF16 | zinc finger protein 16 |
| ZNF322P1 | zinc finger protein 322 pseudogene 1 |
| ZNF350 | zinc finger protein 350 |
| ZNF675 | zinc finger protein 675 |
| ZNF696 | zinc finger protein 696 |