prednisone-1978 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the prednisone-1978 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ACOT11 acyl-CoA thioesterase 11
ADK adenosine kinase
ADRBK2 adrenergic, beta, receptor kinase 2
ANKRD12 ankyrin repeat domain 12
APOC4 apolipoprotein C-IV
ARNT aryl hydrocarbon receptor nuclear translocator
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATXN7 ataxin 7
AZI2 5-azacytidine induced 2
CCPG1 cell cycle progression 1
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CLTCL1 clathrin, heavy chain-like 1
DERL2 derlin 2
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DMXL2 Dmx-like 2
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DUSP2 dual specificity phosphatase 2
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EFCAB2 EF-hand calcium binding domain 2
EI24 etoposide induced 2.4
EID1 EP300 interacting inhibitor of differentiation 1
EIF4E eukaryotic translation initiation factor 4E
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ERN2 endoplasmic reticulum to nucleus signaling 2
EVI5 ecotropic viral integration site 5
FAM134B family with sequence similarity 134, member B
FAM178A family with sequence similarity 178, member A
FAM3A family with sequence similarity 3, member A
FAM3C family with sequence similarity 3, member C
FBXL5 F-box and leucine-rich repeat protein 5
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FMR1 fragile X mental retardation 1
FURIN furin (paired basic amino acid cleaving enzyme)
GABPB1 GA binding protein transcription factor, beta subunit 1
GPR183 G protein-coupled receptor 183
HBEGF heparin-binding EGF-like growth factor
HIRA histone cell cycle regulator
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HP1BP3 heterochromatin protein 1, binding protein 3
HPS4 Hermansky-Pudlak syndrome 4
HTATSF1 HIV-1 Tat specific factor 1
IL10RB interleukin 10 receptor, beta
IRAK3 interleukin-1 receptor-associated kinase 3
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
IVNS1ABP influenza virus NS1A binding protein
JRKL JRK-like
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIFC1 kinesin family member C1
KLHL24 kelch-like family member 24
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
LIN7C lin-7 homolog C (C. elegans)
LMNB1 lamin B1
MAP2K2 mitogen-activated protein kinase kinase 2
MAST2 microtubule associated serine/threonine kinase 2
MEF2A myocyte enhancer factor 2A
NAAA N-acylethanolamine acid amidase
NINJ2 ninjurin 2
NMD3 NMD3 ribosome export adaptor
NPIPB15 nuclear pore complex interacting protein family, member B15
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUCB2 nucleobindin 2
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
NUPL1 nucleoporin like 1
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin
PARP16 poly (ADP-ribose) polymerase family, member 16
PFDN4 prefoldin subunit 4
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLSCR1 phospholipid scramblase 1
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
PPAP2A phosphatidic acid phosphatase type 2A
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRPF39 pre-mRNA processing factor 39
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTP4A1 protein tyrosine phosphatase type IVA, member 1
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RABGGTB Rab geranylgeranyltransferase, beta subunit
RAP1GAP RAP1 GTPase activating protein
RB1 retinoblastoma 1
RECQL RecQ helicase-like
REST RE1-silencing transcription factor
RIOK3 RIO kinase 3
RPS2 ribosomal protein S2
SEC23B Sec23 homolog B (S. cerevisiae)
SEC24D SEC24 family member D
SLK STE20-like kinase
SMNDC1 survival motor neuron domain containing 1
SS18 synovial sarcoma translocation, chromosome 18
TBC1D4 TBC1 domain family, member 4
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TRAPPC10 trafficking protein particle complex 10
USP24 ubiquitin specific peptidase 24
WWC2 WW and C2 domain containing 2
YIPF4 Yip1 domain family, member 4

decreased expression

Symbol Name
ACOT8 acyl-CoA thioesterase 8
ACP2 acid phosphatase 2, lysosomal
ACVR2B activin A receptor, type IIB
ANXA6 annexin A6
ATOX1 antioxidant 1 copper chaperone
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCL2L2 BCL2-like 2
C12ORF49 chromosome 12 open reading frame 49
C1ORF35 chromosome 1 open reading frame 35
C7ORF43 chromosome 7 open reading frame 43
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CD248 CD248 molecule, endosialin
CD38 CD38 molecule
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLASRP CLK4-associating serine/arginine rich protein
CNPY3 canopy FGF signaling regulator 3
CTDNEP1 CTD nuclear envelope phosphatase 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGAT1 diacylglycerol O-acyltransferase 1
DHDDS dehydrodolichyl diphosphate synthase
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DRD5 dopamine receptor D5
EDAR ectodysplasin A receptor
FAM63A family with sequence similarity 63, member A
FLCN folliculin
GDAP2 ganglioside induced differentiation associated protein 2
GORASP1 golgi reassembly stacking protein 1, 65kDa
GSTM3 glutathione S-transferase mu 3 (brain)
GSTM5 glutathione S-transferase mu 5
HMG20A high mobility group 20A
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL4R interleukin 4 receptor
ILK integrin-linked kinase
INO80D INO80 complex subunit D
KAT7 K(lysine) acetyltransferase 7
KCTD20 potassium channel tetramerization domain containing 20
KLF7 Kruppel-like factor 7 (ubiquitous)
KRI1 KRI1 homolog (S. cerevisiae)
LGALS9 lectin, galactoside-binding, soluble, 9
LPPR3 lipid phosphate phosphatase-related protein type 3
LRP3 low density lipoprotein receptor-related protein 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPK10 mitogen-activated protein kinase 10
MAPK3 mitogen-activated protein kinase 3
MAPKBP1 mitogen-activated protein kinase binding protein 1
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MITF microphthalmia-associated transcription factor
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MUC3A mucin 3A, cell surface associated
MXRA8 matrix-remodelling associated 8
MYO19 myosin XIX
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NCF1C neutrophil cytosolic factor 1C pseudogene
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NPM3 nucleophosmin/nucleoplasmin 3
NR1H2 nuclear receptor subfamily 1, group H, member 2
NUBP2 nucleotide binding protein 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PADI1 peptidyl arginine deiminase, type I
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PUS1 pseudouridylate synthase 1
RECQL4 RecQ protein-like 4
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCO2 SCO2 cytochrome c oxidase assembly protein
SDF2L1 stromal cell-derived factor 2-like 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SHPK sedoheptulokinase
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SNF8 SNF8, ESCRT-II complex subunit
SNX6 sorting nexin 6
SP140L SP140 nuclear body protein-like
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STK25 serine/threonine kinase 25
STRA13 stimulated by retinoic acid 13
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYNGR2 synaptogyrin 2
TBL3 transducin (beta)-like 3
TESK2 testis-specific kinase 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TSSC4 tumor suppressing subtransferable candidate 4
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBE2S ubiquitin-conjugating enzyme E2S
UBL4A ubiquitin-like 4A
USB1 U6 snRNA biogenesis 1
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
WDR18 WD repeat domain 18
XDH xanthine dehydrogenase
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZC3H12A zinc finger CCCH-type containing 12A
ZC3H3 zinc finger CCCH-type containing 3
ZNF282 zinc finger protein 282
ZNF443 zinc finger protein 443